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The map label for this gene is nupG [H]

Identifier: 238896496

GI number: 238896496

Start: 4474785

End: 4476038

Strand: Direct

Name: nupG [H]

Synonym: KP1_4677

Alternate gene names: 238896496

Gene position: 4474785-4476038 (Clockwise)

Preceding gene: 238896495

Following gene: 238896498

Centisome position: 85.26

GC content: 56.46

Gene sequence:

>1254_bases
ATGAATCTTAAGCTGCAGCTCAAAATACTGTCGTTCCTGCAGTTCTGCCTTTGGGGGAGCTGGCTCACCACGCTTGGCTC
GTACATGTTTGTCACGCTGAAGTTTGACGGCGCGGCAATCGGCGCAGTGTATAGCTCGCTCGGTATCGCCGCGGTGTTGA
TGCCGACGCTGCTCGGCATCGTCGCCGATAAGTGGATCAGCGCCAAATGGGTATACGCCATCTGCCACCTGGTCGGCGCG
TTAACGCTGTACCTCGCGGCGCAGGTCACCACGCCGGGCGAGATGTTCCTCGTGATCCTGCTTAACTCGCTGGCCTATAT
GCCGACGCTTGGCTTGATCAATACCATCTCCTACTACCGCCTGCAGTCGGCGGGGCTGGATATTGTCACCGATTTCCCGC
CAATTCGTATCTGGGGCACCATCGGCTTTATCCTCGCCATGTGGGGCGTGAGCTTCTCCGGCTTTGAACTGAGCCATATG
CAGCTGTACATTGGCGCGACGCTGTCGGTCCTGCTGACTCTGTTCACCCTGACGCTGCCGCATATTCCGGTCGCCAACGC
CCAGCGCAATCAAAGCTGGACGGAGATGCTCGGCCTGAACGCTTTTGCGCTGTTTAAAAACAAGCGTATGGCTATCTTCT
TTATCTTCTCGATGATGCTCGGCGCCGAGCTGCAAATCACTAACATGTTCGGTAACACCTTCCTGCACAGCTTCGATAAA
GATCCGCTGTTTGCCGGCAGCTTTATCGTCGAGCACGCGTCAGTGCTGATGTCGATTTCGCAGATTTCCGAAACGCTGTT
TATCCTGACCATCCCATTCTTCCTTAGCCGCTACGGCATTAAGAACGTGATGCTTATCAGTATTGTGGCGTGGATGCTGC
GCTTCGGCCTGTTCGCCTTTGGCGACCCGACGCCGTTCGGCACTGTACTGCTGGTGCTGTCGATGATCGTCTACGGCTGC
GCCTTCGACTTCTTTAACATCTCCGGTTCGGTGTTCGTTGAGAAAGAGGTGCGCCCGGAAATCCGCGCCAGCGCTCAGGG
GATGTTCCTGATGATGACCAACGGCTTCGGCTGTATTCTCGGCGGGATGGTGAGCGGCAAAGTCGTCGAACACTTTACCG
TCGAGGGGATCACTGACTGGCAGAGCGTGTGGCTGATTTTCGCCGGCTATTCGCTGGTGCTGGCCTTTGCCTTCGTGGCG
CTGTTCAAATACAAACACGTCAGACAACCGACCGCCGCCCAGCAGAGCGTGTGA

Upstream 100 bases:

>100_bases
AACAGAAGCATTAAGCTAGTGAATGATAGAATCGCATCAAAATAACGGGATTAATGTTATTTTAAAAACATAACAAGCCC
ACATTCGTGAGGATAACTAC

Downstream 100 bases:

>100_bases
TCGGCAAAAGTAAAACGCCCCGCCTGTTCGGCGGGGCGTTTTTTTATCCCTTCAGCACGTAGCCATACAGCCGCTTAATG
CCGTCCGGATCCGTCTCGCT

Product: nucleoside transport protein

Products: NA

Alternate protein names: Nucleoside-transport system protein nupG [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGAAIGAVYSSLGIAAVLMPTLLGIVADKWISAKWVYAICHLVGA
LTLYLAAQVTTPGEMFLVILLNSLAYMPTLGLINTISYYRLQSAGLDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHM
QLYIGATLSVLLTLFTLTLPHIPVANAQRNQSWTEMLGLNAFALFKNKRMAIFFIFSMMLGAELQITNMFGNTFLHSFDK
DPLFAGSFIVEHASVLMSISQISETLFILTIPFFLSRYGIKNVMLISIVAWMLRFGLFAFGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVRPEIRASAQGMFLMMTNGFGCILGGMVSGKVVEHFTVEGITDWQSVWLIFAGYSLVLAFAFVA
LFKYKHVRQPTAAQQSV

Sequences:

>Translated_417_residues
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGAAIGAVYSSLGIAAVLMPTLLGIVADKWISAKWVYAICHLVGA
LTLYLAAQVTTPGEMFLVILLNSLAYMPTLGLINTISYYRLQSAGLDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHM
QLYIGATLSVLLTLFTLTLPHIPVANAQRNQSWTEMLGLNAFALFKNKRMAIFFIFSMMLGAELQITNMFGNTFLHSFDK
DPLFAGSFIVEHASVLMSISQISETLFILTIPFFLSRYGIKNVMLISIVAWMLRFGLFAFGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVRPEIRASAQGMFLMMTNGFGCILGGMVSGKVVEHFTVEGITDWQSVWLIFAGYSLVLAFAFVA
LFKYKHVRQPTAAQQSV
>Mature_417_residues
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGAAIGAVYSSLGIAAVLMPTLLGIVADKWISAKWVYAICHLVGA
LTLYLAAQVTTPGEMFLVILLNSLAYMPTLGLINTISYYRLQSAGLDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHM
QLYIGATLSVLLTLFTLTLPHIPVANAQRNQSWTEMLGLNAFALFKNKRMAIFFIFSMMLGAELQITNMFGNTFLHSFDK
DPLFAGSFIVEHASVLMSISQISETLFILTIPFFLSRYGIKNVMLISIVAWMLRFGLFAFGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVRPEIRASAQGMFLMMTNGFGCILGGMVSGKVVEHFTVEGITDWQSVWLIFAGYSLVLAFAFVA
LFKYKHVRQPTAAQQSV

Specific function: Transports nucleosides with a high affinity. Driven by a proton motive force [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli xapB and yegT [H]

Homologues:

Organism=Escherichia coli, GI87082192, Length=414, Percent_Identity=87.43961352657, Blast_Score=730, Evalue=0.0,
Organism=Escherichia coli, GI1788745, Length=406, Percent_Identity=60.0985221674877, Blast_Score=477, Evalue=1e-136,
Organism=Escherichia coli, GI1788415, Length=417, Percent_Identity=30.9352517985612, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46267; Mature: 46267

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGAAIGAVYSSLGIAAVLMPTLLGI
CCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VADKWISAKWVYAICHLVGALTLYLAAQVTTPGEMFLVILLNSLAYMPTLGLINTISYYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LQSAGLDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHMQLYIGATLSVLLTLFTLTLP
HHCCCCEEEECCCCEEHHHHHHHHHHHHCCCCCCEEEEHHHEEHHHHHHHHHHHHHHHCC
HIPVANAQRNQSWTEMLGLNAFALFKNKRMAIFFIFSMMLGAELQITNMFGNTFLHSFDK
CCCCCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCC
DPLFAGSFIVEHASVLMSISQISETLFILTIPFFLSRYGIKNVMLISIVAWMLRFGLFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
GDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVRPEIRASAQGMFLMMTNGFGCIL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCCEEEEEECCCHHHH
GGMVSGKVVEHFTVEGITDWQSVWLIFAGYSLVLAFAFVALFKYKHVRQPTAAQQSV
HHHHCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGAAIGAVYSSLGIAAVLMPTLLGI
CCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VADKWISAKWVYAICHLVGALTLYLAAQVTTPGEMFLVILLNSLAYMPTLGLINTISYYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LQSAGLDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHMQLYIGATLSVLLTLFTLTLP
HHCCCCEEEECCCCEEHHHHHHHHHHHHCCCCCCEEEEHHHEEHHHHHHHHHHHHHHHCC
HIPVANAQRNQSWTEMLGLNAFALFKNKRMAIFFIFSMMLGAELQITNMFGNTFLHSFDK
CCCCCCCCCCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCC
DPLFAGSFIVEHASVLMSISQISETLFILTIPFFLSRYGIKNVMLISIVAWMLRFGLFAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHC
GDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVRPEIRASAQGMFLMMTNGFGCIL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCCCCEEEEEECCCHHHH
GGMVSGKVVEHFTVEGITDWQSVWLIFAGYSLVLAFAFVALFKYKHVRQPTAAQQSV
HHHHCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3311747; 9278503 [H]