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The map label for this gene is xycH [H]

Identifier: 238896489

GI number: 238896489

Start: 4468808

End: 4470100

Strand: Direct

Name: xycH [H]

Synonym: KP1_4669

Alternate gene names: 238896489

Gene position: 4468808-4470100 (Clockwise)

Preceding gene: 238896488

Following gene: 238896493

Centisome position: 85.14

GC content: 61.87

Gene sequence:

>1293_bases
TTGAACGTAAATCACAGCCAACCACTTCCGGAGCGATGTAATTTTATGAACAGTAAGACCGCATCCCACACCGCGCTGGA
TCGCAGCGATGAGCGCGTTCGTCACGACGAGGGGCTGTTCGGCGCCCTACGCGCGCAGATAACCCGCATCAAAACCGGCG
ATCTCGGCACCGCGCCGGTGATAGCCGGGCTGATTGTGATTTCCCTGGTTTTCACCTTCCTCAACCCGGTCTATATCGCG
CCGAATAACCTGGTGAACCTGCTGTTTGACTGCGCGACGGTCGGGTTTATCTCGCTCGGCATCGTCTGCGTGCTAATGCT
TGGTGAGATAGACCTGTCGGTCGGCTCCATGAGCGGCCTGGCATCGGCTATCGTCGGCGTGCTGTGGGTGAACGCAGGAT
GGCCGCTGGCGGGAGCCATCGCCGTGGCGCTGGCCTGCGGCGTGGCCGTCGGGCTGGTCTACGCGCTGCTGTATACCCGC
GTCGGAATGCCGAGTTTCGTCGCCACTCTCGCCGGCCTGCTGGCGCTGCTGGGTATGCAGCTGTATATCCTCGGGCCGAG
CGGCAGCATCAACCTGCCCTATACTTCGCCGCTGGTGCGCTTTGGCCAACTGCTGGTGATGCCCGGCTGGTTCTCACACC
TGATGGCATTGCTGCCAGGGCTGGCGATCCTTATTTTTGGCCTGAAAAAACGCTCGCGGCGCCTGGCGGCCAATCTTTCC
GCCGAGGGAGTCAGCTCGCTAGTGGCGCGCGCGATCGCGCTGACGATTATCTTCGAGGCCGCGGTGCTTTACCTCAATCA
GGGGCGCGGTATTCCATGGATTTTCGGTCTCTTTGTCGCCTGCGTGATGATCCTCAACTACGCGCTGAAACGGACAAAAT
GGGGTCGCTCGATGTTCGCGGTTGGCGGCAACCGTGAAGCGGCGCGCCGTTCGGGCATTAACGTGCGGGCGATTTATGTG
AGCGCTTTCGTCCTGTGTACCACGCTTGCGACCTTCGGCGGCATTCTCGCGGCGTCGCGACTGGCTTCCGCCAGCCAGCA
GGCCGGCACCGGCGACGTCAACCTCAACGCCATCGCCGCGGCGGTGATCGGCGGCACCAGCCTGTTCGGCGGACGCGGCA
GCGCCTGGTCCGCGCTATTGGGGATCATCGTGATTCAGTCGATTTCAAATGGGCTGACGCTGTTGAACCTGCCGTCTTCG
CTGCGCTATATCATTACCGGCGCGGTACTGGCGATTGCGGTAATCATTGATTCTCTGGCTCGCCGTTCACGCGTGTCGCA
CGGCCGCGCCTGA

Upstream 100 bases:

>100_bases
CGTCTCGGGCGCAACAAAGGGATCTTCACGCCCGATGCTTCTAATCAGGATCTGGTCGCCGTGATCACCGGCGCGACGGA
AAACGCCGTCTCACGCCGGG

Downstream 100 bases:

>100_bases
GTGGAGAAGTGCGCGGCCCAAAGGTATGCGGGCCGCGAAATTTTGATTATTTTAACGAGCCAACCAGCGCTTTGCGGCTG
TCCTCCAGCGATACCACCCG

Product: sugar ABC transport system permease component

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MNVNHSQPLPERCNFMNSKTASHTALDRSDERVRHDEGLFGALRAQITRIKTGDLGTAPVIAGLIVISLVFTFLNPVYIA
PNNLVNLLFDCATVGFISLGIVCVLMLGEIDLSVGSMSGLASAIVGVLWVNAGWPLAGAIAVALACGVAVGLVYALLYTR
VGMPSFVATLAGLLALLGMQLYILGPSGSINLPYTSPLVRFGQLLVMPGWFSHLMALLPGLAILIFGLKKRSRRLAANLS
AEGVSSLVARAIALTIIFEAAVLYLNQGRGIPWIFGLFVACVMILNYALKRTKWGRSMFAVGGNREAARRSGINVRAIYV
SAFVLCTTLATFGGILAASRLASASQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSISNGLTLLNLPSS
LRYIITGAVLAIAVIIDSLARRSRVSHGRA

Sequences:

>Translated_430_residues
MNVNHSQPLPERCNFMNSKTASHTALDRSDERVRHDEGLFGALRAQITRIKTGDLGTAPVIAGLIVISLVFTFLNPVYIA
PNNLVNLLFDCATVGFISLGIVCVLMLGEIDLSVGSMSGLASAIVGVLWVNAGWPLAGAIAVALACGVAVGLVYALLYTR
VGMPSFVATLAGLLALLGMQLYILGPSGSINLPYTSPLVRFGQLLVMPGWFSHLMALLPGLAILIFGLKKRSRRLAANLS
AEGVSSLVARAIALTIIFEAAVLYLNQGRGIPWIFGLFVACVMILNYALKRTKWGRSMFAVGGNREAARRSGINVRAIYV
SAFVLCTTLATFGGILAASRLASASQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSISNGLTLLNLPSS
LRYIITGAVLAIAVIIDSLARRSRVSHGRA
>Mature_430_residues
MNVNHSQPLPERCNFMNSKTASHTALDRSDERVRHDEGLFGALRAQITRIKTGDLGTAPVIAGLIVISLVFTFLNPVYIA
PNNLVNLLFDCATVGFISLGIVCVLMLGEIDLSVGSMSGLASAIVGVLWVNAGWPLAGAIAVALACGVAVGLVYALLYTR
VGMPSFVATLAGLLALLGMQLYILGPSGSINLPYTSPLVRFGQLLVMPGWFSHLMALLPGLAILIFGLKKRSRRLAANLS
AEGVSSLVARAIALTIIFEAAVLYLNQGRGIPWIFGLFVACVMILNYALKRTKWGRSMFAVGGNREAARRSGINVRAIYV
SAFVLCTTLATFGGILAASRLASASQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSISNGLTLLNLPSS
LRYIITGAVLAIAVIIDSLARRSRVSHGRA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=374, Percent_Identity=35.0267379679144, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790191, Length=153, Percent_Identity=42.483660130719, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788896, Length=170, Percent_Identity=40.5882352941176, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=36.1842105263158, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693152, Length=155, Percent_Identity=35.4838709677419, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082395, Length=318, Percent_Identity=28.3018867924528, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788471, Length=136, Percent_Identity=39.7058823529412, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787793, Length=145, Percent_Identity=36.551724137931, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 45133; Mature: 45133

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVNHSQPLPERCNFMNSKTASHTALDRSDERVRHDEGLFGALRAQITRIKTGDLGTAPV
CCCCCCCCCHHHHCCCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHH
IAGLIVISLVFTFLNPVYIAPNNLVNLLFDCATVGFISLGIVCVLMLGEIDLSVGSMSGL
HHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ASAIVGVLWVNAGWPLAGAIAVALACGVAVGLVYALLYTRVGMPSFVATLAGLLALLGMQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCE
LYILGPSGSINLPYTSPLVRFGQLLVMPGWFSHLMALLPGLAILIFGLKKRSRRLAANLS
EEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AEGVSSLVARAIALTIIFEAAVLYLNQGRGIPWIFGLFVACVMILNYALKRTKWGRSMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VGGNREAARRSGINVRAIYVSAFVLCTTLATFGGILAASRLASASQQAGTGDVNLNAIAA
ECCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AVIGGTSLFGGRGSAWSALLGIIVIQSISNGLTLLNLPSSLRYIITGAVLAIAVIIDSLA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
RRSRVSHGRA
HHHHHCCCCC
>Mature Secondary Structure
MNVNHSQPLPERCNFMNSKTASHTALDRSDERVRHDEGLFGALRAQITRIKTGDLGTAPV
CCCCCCCCCHHHHCCCCCCCCHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHH
IAGLIVISLVFTFLNPVYIAPNNLVNLLFDCATVGFISLGIVCVLMLGEIDLSVGSMSGL
HHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ASAIVGVLWVNAGWPLAGAIAVALACGVAVGLVYALLYTRVGMPSFVATLAGLLALLGMQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCE
LYILGPSGSINLPYTSPLVRFGQLLVMPGWFSHLMALLPGLAILIFGLKKRSRRLAANLS
EEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AEGVSSLVARAIALTIIFEAAVLYLNQGRGIPWIFGLFVACVMILNYALKRTKWGRSMFA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VGGNREAARRSGINVRAIYVSAFVLCTTLATFGGILAASRLASASQQAGTGDVNLNAIAA
ECCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AVIGGTSLFGGRGSAWSALLGIIVIQSISNGLTLLNLPSSLRYIITGAVLAIAVIIDSLA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
RRSRVSHGRA
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]