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The map label for this gene is rpiA [H]

Identifier: 238896459

GI number: 238896459

Start: 4438295

End: 4439032

Strand: Reverse

Name: rpiA [H]

Synonym: KP1_4637

Alternate gene names: 238896459

Gene position: 4439032-4438295 (Counterclockwise)

Preceding gene: 238896461

Following gene: 238896457

Centisome position: 84.58

GC content: 58.54

Gene sequence:

>738_bases
GTGATCTGCATCGCAGGGACATTTCCACTATCGATGTTCTATAATGCGCCACAGGCATTCACATCTCGGACCAGAATTAT
GACGCAGGATGAACTGAAAAAAGCGGTAGGTTGGGCAGCACTGCAATATGTACAGCCAGGGACTATTGTCGGCGTAGGCA
CCGGCTCGACGGCGGCCCATTTTATTGACGCGCTGGGCACCATGAAGGGGCAGATCGAAGGGGCGGTTTCCAGCTCCGAC
GCCTCCACCGAGAAGCTGAAAAGCCTCGGGATCACCGTCTTCGATCTTAACAGCGTCGATCGCCTGGGGATCTATGTTGA
CGGCGCGGATGAGATCAACGGCCATATGCAGATGATCAAAGGCGGCGGCGCGGCGCTGACCCGTGAAAAGATCATCGCCT
CGGTCGCGGATAAATTTATCTGCATCGCCGACGCCTCCAAGCAGGTCGATATTCTGGGCAAGTTCCCGCTGCCGGTGGAA
GTCATTCCGATGGCGCGCAGCGCCGTGGCGCGTCAGCTGGTCAAGCTGGGCGGCCGTCCAGAGTACCGTCAGGGCGTGGT
GACCGATAACGGCAACGTGATCCTTGACGTGCACGGCCTGGAAATTCTCGATGCGATCGCGCTGGAAAACGCGATCAACG
GTATTCCTGGCGTCGTCACCGTGGGGCTGTTCGCCAACCGTGGCGCCGACGTGGCGCTGATTGGCACTGCCGACGGCGTG
AAGACCATCGTAAAATAG

Upstream 100 bases:

>100_bases
GGTCGTTTCATTATTCTGGCGTGCCCCCATAACTAATCGTTATCTCGCACTATGACATAAATTTTTATTTGATACAGACG
AAATTGGTCTGTTCAGTTGT

Downstream 100 bases:

>100_bases
TCTGTCCGCAGGGAGCCGACCGGCTCCCTCGCAAATATTTTTTCATCAGGTGCAATTTGGTGACTTCTGTCACATTTATG
CAACCATTCTGATTTACACG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MICIAGTFPLSMFYNAPQAFTSRTRIMTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSD
ASTEKLKSLGITVFDLNSVDRLGIYVDGADEINGHMQMIKGGGAALTREKIIASVADKFICIADASKQVDILGKFPLPVE
VIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGLEILDAIALENAINGIPGVVTVGLFANRGADVALIGTADGV
KTIVK

Sequences:

>Translated_245_residues
MICIAGTFPLSMFYNAPQAFTSRTRIMTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSD
ASTEKLKSLGITVFDLNSVDRLGIYVDGADEINGHMQMIKGGGAALTREKIIASVADKFICIADASKQVDILGKFPLPVE
VIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGLEILDAIALENAINGIPGVVTVGLFANRGADVALIGTADGV
KTIVK
>Mature_245_residues
MICIAGTFPLSMFYNAPQAFTSRTRIMTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSD
ASTEKLKSLGITVFDLNSVDRLGIYVDGADEINGHMQMIKGGGAALTREKIIASVADKFICIADASKQVDILGKFPLPVE
VIPMARSAVARQLVKLGGRPEYRQGVVTDNGNVILDVHGLEILDAIALENAINGIPGVVTVGLFANRGADVALIGTADGV
KTIVK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=37.0535714285714, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1789280, Length=219, Percent_Identity=95.8904109589041, Blast_Score=420, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17551758, Length=229, Percent_Identity=35.8078602620087, Blast_Score=114, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6324669, Length=216, Percent_Identity=31.9444444444444, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281364072, Length=216, Percent_Identity=33.7962962962963, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 25655; Mature: 25655

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICIAGTFPLSMFYNAPQAFTSRTRIMTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAH
CEEEEECCCHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHH
FIDALGTMKGQIEGAVSSSDASTEKLKSLGITVFDLNSVDRLGIYVDGADEINGHMQMIK
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCEEEEEECCCHHCCCEEEEEE
GGGAALTREKIIASVADKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRP
CCCCHHHHHHHHHHHHHCEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCC
EYRQGVVTDNGNVILDVHGLEILDAIALENAINGIPGVVTVGLFANRGADVALIGTADGV
CHHCCEEECCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCH
KTIVK
HHHCC
>Mature Secondary Structure
MICIAGTFPLSMFYNAPQAFTSRTRIMTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAH
CEEEEECCCHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCEEEECCCCHHHH
FIDALGTMKGQIEGAVSSSDASTEKLKSLGITVFDLNSVDRLGIYVDGADEINGHMQMIK
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCEEEEEECCCHHCCCEEEEEE
GGGAALTREKIIASVADKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRP
CCCCHHHHHHHHHHHHHCEEEEECCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCC
EYRQGVVTDNGNVILDVHGLEILDAIALENAINGIPGVVTVGLFANRGADVALIGTADGV
CHHCCEEECCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCH
KTIVK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA