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The map label for this gene is ygdL [H]

Identifier: 238896284

GI number: 238896284

Start: 4266425

End: 4267246

Strand: Reverse

Name: ygdL [H]

Synonym: KP1_4444

Alternate gene names: 238896284

Gene position: 4267246-4266425 (Counterclockwise)

Preceding gene: 238896285

Following gene: 238896281

Centisome position: 81.3

GC content: 62.04

Gene sequence:

>822_bases
ATGTCTGTTGTAATCAGCGATGCCTGGCGCCAGCGTTTTGGCGGTACGGCACGTTTATATGGTGAAAAAGCGCTGCAATG
TTTTGCCGACGCCCACGTCTGCGTGGTCGGGATCGGCGGGGTCGGCTCCTGGGCGGCGGAAGCGCTGGCGCGGACCGGCA
TCGGGGCGATCACCCTTATCGATATGGACGATGTCTGCGTCACCAACACCAATCGTCAGATCCACGCCCTCAGCGGCAAC
GTCGGGCTGGCGAAAGCGGAGGTGATGGCGGAGCGTATTCGTCTCATCAACCCGGAGTGTCGGGTGACGGTGGTGGATGA
TTTCGTGACCCCGGAAAACGTGGCGGAATATCTTGGCGTCGGCTTTAGCTATGTTATCGACGCGATCGATAGCGTCCGGC
CGAAAGCGGCGCTTATCGCCTGGTGTCGCCGCTACAAGGTGCCGCTGGTGACTACCGGCGGGGCGGGTGGTCAGATTGAC
CCAACGCAGATCCAGGTCGCTGACCTGGCGAAGACCATCCAGGATCCGCTGGCGGCCAAACTGCGCGAGCGGCTGAAAAG
CCAGTTTGGGGTGGTGAAAAACAGCAAAGGTAAGCTCGGTGTAGACTGCGTCTTCTCTACGGAAGCGCTGGTCTACCCGC
AGGCGGACGGCAGCGTCTGCGCAATGAAGAGCACGGCGGAAGGGCCGAAGCGGATGGACTGCGCTTCCGGCTTTGGCGCG
GCGACGATGGTGACCGCGACCTTCGGCTTCGTCGCGGTGTCGCATGCCCTGAAGAAGATGCTGGCGAAAGCGCAGCGTGA
CGCTGCGGCTGCCGGAAAGTAG

Upstream 100 bases:

>100_bases
TTTTAGCGGCTAACTCCCCTGGCCATGCCTGTTGACCAGGGCGCCCGGATGACGCCGTTTACGGCGGCCTCCGGGCGCTG
TCATTTTGTTCTGAGGTTCT

Downstream 100 bases:

>100_bases
TTTGCCCACCGGGCGCGGCGGCGGGAAAGCGAAATCGTGAGATTACCTTTCGCGGGCGGCGGCGAGCACCGCCTCGCTCA
GGGCGCTGAGGCCCTGGCTG

Product: putative enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSVVISDAWRQRFGGTARLYGEKALQCFADAHVCVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALSGN
VGLAKAEVMAERIRLINPECRVTVVDDFVTPENVAEYLGVGFSYVIDAIDSVRPKAALIAWCRRYKVPLVTTGGAGGQID
PTQIQVADLAKTIQDPLAAKLRERLKSQFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKSTAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKMLAKAQRDAAAAGK

Sequences:

>Translated_273_residues
MSVVISDAWRQRFGGTARLYGEKALQCFADAHVCVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALSGN
VGLAKAEVMAERIRLINPECRVTVVDDFVTPENVAEYLGVGFSYVIDAIDSVRPKAALIAWCRRYKVPLVTTGGAGGQID
PTQIQVADLAKTIQDPLAAKLRERLKSQFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKSTAEGPKRMDCASGFGA
ATMVTATFGFVAVSHALKKMLAKAQRDAAAAGK
>Mature_272_residues
SVVISDAWRQRFGGTARLYGEKALQCFADAHVCVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALSGNV
GLAKAEVMAERIRLINPECRVTVVDDFVTPENVAEYLGVGFSYVIDAIDSVRPKAALIAWCRRYKVPLVTTGGAGGQIDP
TQIQVADLAKTIQDPLAAKLRERLKSQFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKSTAEGPKRMDCASGFGAA
TMVTATFGFVAVSHALKKMLAKAQRDAAAAGK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI4885649, Length=137, Percent_Identity=32.1167883211679, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789177, Length=266, Percent_Identity=92.4812030075188, Blast_Score=509, Evalue=1e-146,
Organism=Escherichia coli, GI87082356, Length=136, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787048, Length=131, Percent_Identity=34.3511450381679, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322825, Length=202, Percent_Identity=32.1782178217822, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6321790, Length=205, Percent_Identity=23.9024390243902, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24660640, Length=132, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582879, Length=124, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28813; Mature: 28681

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVISDAWRQRFGGTARLYGEKALQCFADAHVCVVGIGGVGSWAAEALARTGIGAITLI
CEEEECHHHHHHHCCCEEHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALSGNVGLAKAEVMAERIRLINPECRVTVVDDFVTPENVAEYLGV
ECCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCC
GFSYVIDAIDSVRPKAALIAWCRRYKVPLVTTGGAGGQIDPTQIQVADLAKTIQDPLAAK
CHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRERLKSQFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKSTAEGPKRMDCASGFGA
HHHHHHHHHCCEECCCCCCCEEEEEECCEEEEECCCCCEEEECCCCCCCCHHHHHCCCCH
ATMVTATFGFVAVSHALKKMLAKAQRDAAAAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVVISDAWRQRFGGTARLYGEKALQCFADAHVCVVGIGGVGSWAAEALARTGIGAITLI
EEEECHHHHHHHCCCEEHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEE
DMDDVCVTNTNRQIHALSGNVGLAKAEVMAERIRLINPECRVTVVDDFVTPENVAEYLGV
ECCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCC
GFSYVIDAIDSVRPKAALIAWCRRYKVPLVTTGGAGGQIDPTQIQVADLAKTIQDPLAAK
CHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRERLKSQFGVVKNSKGKLGVDCVFSTEALVYPQADGSVCAMKSTAEGPKRMDCASGFGA
HHHHHHHHHCCEECCCCCCCEEEEEECCEEEEECCCCCEEEECCCCCCCCHHHHHCCCCH
ATMVTATFGFVAVSHALKKMLAKAQRDAAAAGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]