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The map label for this gene is licC [H]

Identifier: 238896194

GI number: 238896194

Start: 4167622

End: 4168944

Strand: Direct

Name: licC [H]

Synonym: KP1_4343

Alternate gene names: 238896194

Gene position: 4167622-4168944 (Clockwise)

Preceding gene: 238896193

Following gene: 238896195

Centisome position: 79.41

GC content: 60.02

Gene sequence:

>1323_bases
ATGAGCTCTCTGTACGCTAAACTGATCGACGTGATCGAACGGCAGATCACGCCTATGGCCGGCGCGATCGGCCAGCAAAA
ATATGTCACCTCGATCCGCGATGGCTTTATCACTGCCCTGCCCTTTATGATCGTCGGCTCGTTCCTGTTGGTGTTTATCT
TCCCGCCGTTTTCTCCGGATACGACGTGGGGGTTTGCCCGCGCCTGGCTGCAATTTTCGCTCGATCATCGCGATGCGCTG
ATGCTGCCGTTCAACTTCAGCATGGGGGTGATGACCCTGTTTATCGCCGTCGGGATCGCCGCCAGCCTCGCCAAACACCA
TCATCTGGACTCGCTGACCGCCGGGATGCTGTCGCTGATGTCGTTTCTGCTGGTAGCCGCGCCGCTGAAAGATGGCCAGA
TCTCTACTGCCTACTTCTCCGGTCAGGGGATCTTTACCGCCATTCTGGTGGCCATCTATTCCACCGAGCTGTACGCCTTC
CTCAAACGGCATAACATCACCATTCGCCTGCCGCCGGAAGTGCCTGCCGGGGTGGCGCGCTCGTTTGAAATCCTGATCCC
GGTGCTGGCGATCATTCTGACGCTGCATCCGCTGAACCTGTTTATCGAAGCCCAGCTGGGGATGATCATTCCGGAAGCGA
TCATGTCGCTGGTGAAGCCGCTGGTCGCGGCTTCCGATACGCTGCCGGCGATCCTGCTGTCGGTGCTGGTCTGTCAGGTG
CTGTGGTTCGCCGGGATCCACGGCGCGCTGATCGTCACCGGGATCATGAACCCGTTCTGGATGGCCAACCTGTCGGTCAA
TCAGGCGGCCATGGCGGCAGGTACCGCTATCCCGCACATCTATGTCCAGGGCTTCTGGGATCACTATCTGCTGATCGGCG
GCGTCGGCTCCACCCTGCCGCTGGCGCTGATGCTGCTGCGCAGCAAGGCCGTGCATCTGCGGACGATCGGCCGGATGGGG
GTCGTGCCGGGCGTATTTAACATCAACGAACCGATTCTGTTTGGCGCGCCGATCATCATGAACCCGCTGTTTTTCCTGCC
GTTCGTGCTGGTGCCGATGGTCAACGCGACCCTGGCGTACTTCGCGCTGAAGCTGGACCTGGTCAGCCGCGTAGTGTCGA
TGACGCCGTGGACAACGCCGGCGCCTATCGGCGCCTCGTGGGCGGCGAACTGGAGCTTTAGCCCGGTGATCCTGTGCCTC
ATTTGTATGGCTACCGCCATGGTGATGTACCTGCCATTTCTCAAAGCTTACGAAAAACAGCTGCTGGCCCAGGAACGTGA
AAACGCCGTCGGCCAGGCTGACAACGCGGCGCAAACCGCTTAA

Upstream 100 bases:

>100_bases
CGTCGAACCCATCAATATGATGGACTACGGCATGCAAAAAGGCGCCGCGGTCCTTGATTTCGCCCTTTCCCTTATCGAAA
ACAAGAACTAAGGAAAGATC

Downstream 100 bases:

>100_bases
CGCTAACGATTCAGAGGATAATCATGGAATTAGAAGAACAGGTGATGGGGATCATCATCAATGCCGGCCAGTCACGTAGC
CTGTGCTACGAAGCGCTGCA

Product: putative phosphotransferase protein

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSSLYAKLIDVIERQITPMAGAIGQQKYVTSIRDGFITALPFMIVGSFLLVFIFPPFSPDTTWGFARAWLQFSLDHRDAL
MLPFNFSMGVMTLFIAVGIAASLAKHHHLDSLTAGMLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAF
LKRHNITIRLPPEVPAGVARSFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQV
LWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGVGSTLPLALMLLRSKAVHLRTIGRMG
VVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVNATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCL
ICMATAMVMYLPFLKAYEKQLLAQERENAVGQADNAAQTA

Sequences:

>Translated_440_residues
MSSLYAKLIDVIERQITPMAGAIGQQKYVTSIRDGFITALPFMIVGSFLLVFIFPPFSPDTTWGFARAWLQFSLDHRDAL
MLPFNFSMGVMTLFIAVGIAASLAKHHHLDSLTAGMLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAF
LKRHNITIRLPPEVPAGVARSFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQV
LWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGVGSTLPLALMLLRSKAVHLRTIGRMG
VVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVNATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCL
ICMATAMVMYLPFLKAYEKQLLAQERENAVGQADNAAQTA
>Mature_439_residues
SSLYAKLIDVIERQITPMAGAIGQQKYVTSIRDGFITALPFMIVGSFLLVFIFPPFSPDTTWGFARAWLQFSLDHRDALM
LPFNFSMGVMTLFIAVGIAASLAKHHHLDSLTAGMLSLMSFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFL
KRHNITIRLPPEVPAGVARSFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQVL
WFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGVGSTLPLALMLLRSKAVHLRTIGRMGV
VPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVNATLAYFALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLI
CMATAMVMYLPFLKAYEKQLLAQERENAVGQADNAAQTA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=461, Percent_Identity=31.236442516269, Blast_Score=201, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 47875; Mature: 47744

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLYAKLIDVIERQITPMAGAIGQQKYVTSIRDGFITALPFMIVGSFLLVFIFPPFSPD
CCHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTWGFARAWLQFSLDHRDALMLPFNFSMGVMTLFIAVGIAASLAKHHHLDSLTAGMLSLM
CCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVPAGVAR
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHH
SFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQV
HHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGVGSTLP
HHHHCCHHHHHHHHHCCCHHEECCCCCHHHHHHCCCCCHHHEEHHHHHEEEECCCCHHHH
LALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVNATLAY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHH
FALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLKAYEKQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAQERENAVGQADNAAQTA
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SSLYAKLIDVIERQITPMAGAIGQQKYVTSIRDGFITALPFMIVGSFLLVFIFPPFSPD
CHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TTWGFARAWLQFSLDHRDALMLPFNFSMGVMTLFIAVGIAASLAKHHHLDSLTAGMLSLM
CCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFLLVAAPLKDGQISTAYFSGQGIFTAILVAIYSTELYAFLKRHNITIRLPPEVPAGVAR
HHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHH
SFEILIPVLAIILTLHPLNLFIEAQLGMIIPEAIMSLVKPLVAASDTLPAILLSVLVCQV
HHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LWFAGIHGALIVTGIMNPFWMANLSVNQAAMAAGTAIPHIYVQGFWDHYLLIGGVGSTLP
HHHHCCHHHHHHHHHCCCHHEECCCCCHHHHHHCCCCCHHHEEHHHHHEEEECCCCHHHH
LALMLLRSKAVHLRTIGRMGVVPGVFNINEPILFGAPIIMNPLFFLPFVLVPMVNATLAY
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHH
FALKLDLVSRVVSMTPWTTPAPIGASWAANWSFSPVILCLICMATAMVMYLPFLKAYEKQ
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAQERENAVGQADNAAQTA
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]