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The map label for this gene is hypD [H]

Identifier: 238896186

GI number: 238896186

Start: 4156102

End: 4157223

Strand: Direct

Name: hypD [H]

Synonym: KP1_4334

Alternate gene names: 238896186

Gene position: 4156102-4157223 (Clockwise)

Preceding gene: 238896185

Following gene: 238896187

Centisome position: 79.19

GC content: 63.1

Gene sequence:

>1122_bases
ATGCGTTACGTAGATGAATACCGCGCCCCCGAACAGGTGATGCAGCTGGTGGCCCATCTTCAGCAGCGTGCTCGTCTGCT
GCCGCACACCGCCGCGCGACCGCTGCGCATCATGGAGGTCTGCGGCGGCCATACCCATGCCATTTTTAAATTCGGGCTCG
ACCAACTGTTGCCGGAGAACATCGAATTTATTCATGGTCCCGGCTGCCCGGTGTGCGTCCTGCCGATGGGGCGCATCGAT
GCCTGCATTGAGATTGCCAGCCGCCCGGGAGTGATCTTCTGCACCTTCGGCGACGCCATGCGCGTGCCGGGTAAAAACGG
CTCGCTTCTGCAGGCGAAAGCCCGCGGCGCCGATGTCCGCATCGTTTACTCGCCGATGGACGCTCTGCGGCTGGCGCAGC
AAAATCCGCAGCGCGAGGTGGTCTTTTTTGGTCTCGGTTTCGAAACCACCATGCCCGCTACCGCCCTGACCCTGCGTCAG
GCGCGAGAGCGCAACGTCGATAACTTCTACTTTTTCTGCCAGCACATCACCCTGCTGCCGACCCTGCGCAGCCTGCTGGA
CCAGCCGGAGAACGGAATCGACGCCTTTCTCGCCCCGGGCCACGTCAGTATGGTGATCGGCACCGAGGCCTACGGCTTTA
TCGCCAGCGACTATCACCGTCCTTTAGTGGTCGCCGGTTTCGAACCGCTTGATCTACTGCAAGGCGCGGTGATGCTGGTT
GAGCAGACAATAGCGCAGCGCAGCGATGTGGAAAATCAGTACCGTCGCGTGGTGCCGGATGCCGGCAACCCGCTGGCGCA
GGCGGCGATGGCCGACGTCTTCCGCCTGGATGGCGACAGCGAATGGCGCGGCCTGGGGGTCATCAGCGACTCCGGCGTGC
AGCTTACGCCAGCCTATCAGCGCTTCGATGCCGAGGCGCATTTTCACCCGGCGCCGCAGCGCGTGTGCGACGACCCGCGC
GCCCGCTGCGGCGAGGTGCTGACCGGCCGCTGTAAACCGCACCAGTGCCCGCTCTTCGCCAGCACCTGCAATCCGCAAAG
CGCCTTTGGCGCGCTAATGGTCTCCTCTGAAGGGGCCTGCGCCGCCTGGTATCAATATCGCAGTCAGGAAAATGAAGTAT
GA

Upstream 100 bases:

>100_bases
TCATTAATGAATCCGAAGCCCGCGACACCCTCGAGGCGCTGCAAAATATGTTTGACGTGGAGCCGGACGTCGGCGCGCTG
CTGTACGGCGAGGAGCGATA

Downstream 100 bases:

>100_bases
AAAGCGTCCAGTTAGCCCACGGTAGCGGGGGACAGGCAATGCAACAGCTGATCGGCGACCTGTTTATGCAGGCCTTCGCC
AACCCCTGGCTGGCGGAGCA

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRYVDEYRAPEQVMQLVAHLQQRARLLPHTAARPLRIMEVCGGHTHAIFKFGLDQLLPENIEFIHGPGCPVCVLPMGRID
ACIEIASRPGVIFCTFGDAMRVPGKNGSLLQAKARGADVRIVYSPMDALRLAQQNPQREVVFFGLGFETTMPATALTLRQ
ARERNVDNFYFFCQHITLLPTLRSLLDQPENGIDAFLAPGHVSMVIGTEAYGFIASDYHRPLVVAGFEPLDLLQGAVMLV
EQTIAQRSDVENQYRRVVPDAGNPLAQAAMADVFRLDGDSEWRGLGVISDSGVQLTPAYQRFDAEAHFHPAPQRVCDDPR
ARCGEVLTGRCKPHQCPLFASTCNPQSAFGALMVSSEGACAAWYQYRSQENEV

Sequences:

>Translated_373_residues
MRYVDEYRAPEQVMQLVAHLQQRARLLPHTAARPLRIMEVCGGHTHAIFKFGLDQLLPENIEFIHGPGCPVCVLPMGRID
ACIEIASRPGVIFCTFGDAMRVPGKNGSLLQAKARGADVRIVYSPMDALRLAQQNPQREVVFFGLGFETTMPATALTLRQ
ARERNVDNFYFFCQHITLLPTLRSLLDQPENGIDAFLAPGHVSMVIGTEAYGFIASDYHRPLVVAGFEPLDLLQGAVMLV
EQTIAQRSDVENQYRRVVPDAGNPLAQAAMADVFRLDGDSEWRGLGVISDSGVQLTPAYQRFDAEAHFHPAPQRVCDDPR
ARCGEVLTGRCKPHQCPLFASTCNPQSAFGALMVSSEGACAAWYQYRSQENEV
>Mature_373_residues
MRYVDEYRAPEQVMQLVAHLQQRARLLPHTAARPLRIMEVCGGHTHAIFKFGLDQLLPENIEFIHGPGCPVCVLPMGRID
ACIEIASRPGVIFCTFGDAMRVPGKNGSLLQAKARGADVRIVYSPMDALRLAQQNPQREVVFFGLGFETTMPATALTLRQ
ARERNVDNFYFFCQHITLLPTLRSLLDQPENGIDAFLAPGHVSMVIGTEAYGFIASDYHRPLVVAGFEPLDLLQGAVMLV
EQTIAQRSDVENQYRRVVPDAGNPLAQAAMADVFRLDGDSEWRGLGVISDSGVQLTPAYQRFDAEAHFHPAPQRVCDDPR
ARCGEVLTGRCKPHQCPLFASTCNPQSAFGALMVSSEGACAAWYQYRSQENEV

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=372, Percent_Identity=84.6774193548387, Blast_Score=669, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41258; Mature: 41258

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVDEYRAPEQVMQLVAHLQQRARLLPHTAARPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHCHHHHCCCC
IEFIHGPGCPVCVLPMGRIDACIEIASRPGVIFCTFGDAMRVPGKNGSLLQAKARGADVR
CCEEECCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEECCCCEEE
IVYSPMDALRLAQQNPQREVVFFGLGFETTMPATALTLRQARERNVDNFYFFCQHITLLP
EEECCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLRSLLDQPENGIDAFLAPGHVSMVIGTEAYGFIASDYHRPLVVAGFEPLDLLQGAVMLV
HHHHHHCCCCCCCCEEECCCEEEEEECCCHHEEHHCCCCCCEEEECCCHHHHHHHHHHHH
EQTIAQRSDVENQYRRVVPDAGNPLAQAAMADVFRLDGDSEWRGLGVISDSGVQLTPAYQ
HHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECCHHH
RFDAEAHFHPAPQRVCDDPRARCGEVLTGRCKPHQCPLFASTCNPQSAFGALMVSSEGAC
HCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHEEEEEECCCCH
AAWYQYRSQENEV
HHHHHHHHCCCCC
>Mature Secondary Structure
MRYVDEYRAPEQVMQLVAHLQQRARLLPHTAARPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHCHHHHCCCC
IEFIHGPGCPVCVLPMGRIDACIEIASRPGVIFCTFGDAMRVPGKNGSLLQAKARGADVR
CCEEECCCCCEEEECCCHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEECCCCEEE
IVYSPMDALRLAQQNPQREVVFFGLGFETTMPATALTLRQARERNVDNFYFFCQHITLLP
EEECCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLRSLLDQPENGIDAFLAPGHVSMVIGTEAYGFIASDYHRPLVVAGFEPLDLLQGAVMLV
HHHHHHCCCCCCCCEEECCCEEEEEECCCHHEEHHCCCCCCEEEECCCHHHHHHHHHHHH
EQTIAQRSDVENQYRRVVPDAGNPLAQAAMADVFRLDGDSEWRGLGVISDSGVQLTPAYQ
HHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEECCHHH
RFDAEAHFHPAPQRVCDDPRARCGEVLTGRCKPHQCPLFASTCNPQSAFGALMVSSEGAC
HCCCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCEEECCCCCHHHHEEEEEECCCCH
AAWYQYRSQENEV
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]