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The map label for this gene is ygbD [H]

Identifier: 238896166

GI number: 238896166

Start: 4136797

End: 4137930

Strand: Direct

Name: ygbD [H]

Synonym: KP1_4312

Alternate gene names: 238896166

Gene position: 4136797-4137930 (Clockwise)

Preceding gene: 238896165

Following gene: 238896171

Centisome position: 78.82

GC content: 61.73

Gene sequence:

>1134_bases
ATGAGTGATGGCATCGTCATCATCGGCTCGGGCTTCGCGGCCCGCCAGCTGGTGAAAAATATTCGTAAGCAGGATGCGCA
AATCCCGCTGACCCTCATCGCCGCCGATAGCATGGATGAATACAACAAACCGGACCTCAGCCATGTCATCAGCCGCGGAC
AGAAGGCCGACGATCTGACCCTGCAAAGTGCCGGCGAGTTCGCCGAGCAGTACACTCTGCGTCTGTTTCCCCATACCTGG
GTAAGCGATATCGACGCCGAAAACCGGTTAGTGAAGAGCCAGGATAACCAGTGGCGCTACGACAAACTGGTGCTGGCCAC
CGGCGCGACGCCGTTTATCCCGTCGGTGCCGGGGCGCGAGCTGATGCTAACGCTCAATAGCCAGCGCGAATATGGCGCGG
CGCAGAGCCGGCTGCACGACGCGAAGCGCGTGCTGATCGTCGGCGGCGGCCTGATTGGCTGCGAACTGGCGATGGATTTC
TGCCGCGCCGGTAAAGCGGTAACGGTAGTCGATAACTCCGCCAGCGTGCTGGCGGCGCTGATGCCGCCGGAGGCCAGCAG
CCGCCTGCAGCATCGGCTCACCGAGATGGGCGTACATCTGATGCTGAAAACGCAGCTGGAGGGGCTGGAGCAAACCGCCG
ACGGCATTCGCGTCAGTCTCGATCGCCAGCGCGCGATAACCGTCGATGCGGTGGTGGCCGCCGCCGGCCTGCGCCCGGAA
ACGTCGCTGGCGCGCCACGCCGGACTGCAGATTAACCGCGGTATTGTGGTCAATAGCCAGCTGCAAACCAGCGACCCGGC
GATTTATGCGCTCGGCGACTGTGCGGAAATCAACGGCGTGGTACTGCCGTTCCTGCAGCCGATTTTACTCAGCGCCATGT
GCCTGAGTAAAAATCTGCTGGCGCAGGCGGGAGAACTCAAGCTGCCGCCAATGCTGGTGAAGGTGAAAACCCCGGATCTG
CCGCTGCATCTGGCCGGCGACACCCGCCGCGACGATCTGACGTGGAACATCGTGGCCGCCAAAGAGGGGCTGGTAGCGAA
AGGCGTGGATGCCGAAAACCAGCTGCGGGCCTTTGTGGTCAGCGAAGACAAAATGAAGGAAGCCTTTGCGCTGCTCAAGC
AACTGGTAAGTTGA

Upstream 100 bases:

>100_bases
TACAGCCGGGTACACCGTGGAGTGAAGTGCCGGACAATTTCCTCTGCCCTGAGTGTTCTCTTGGCAAAGATGTCTTTAAC
GTACTGGCGACGGAGGCAAA

Downstream 100 bases:

>100_bases
TGGTTTTCCCGGCTTGCGGCGTAAACGCCTTAGCCGGGCTACGGTATTGTCCTGGTAGCCCGGCTAAGCGCAGCGCAAGC
CGGGAACATATCCAGCCTAG

Product: nitric oxide reductase

Products: NAD; reduced flavorubredoxin; H2O [C]

Alternate protein names: Flavorubredoxin reductase; FlRd-reductase; FlavoRb reductase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSDGIVIIGSGFAARQLVKNIRKQDAQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLTLQSAGEFAEQYTLRLFPHTW
VSDIDAENRLVKSQDNQWRYDKLVLATGATPFIPSVPGRELMLTLNSQREYGAAQSRLHDAKRVLIVGGGLIGCELAMDF
CRAGKAVTVVDNSASVLAALMPPEASSRLQHRLTEMGVHLMLKTQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPE
TSLARHAGLQINRGIVVNSQLQTSDPAIYALGDCAEINGVVLPFLQPILLSAMCLSKNLLAQAGELKLPPMLVKVKTPDL
PLHLAGDTRRDDLTWNIVAAKEGLVAKGVDAENQLRAFVVSEDKMKEAFALLKQLVS

Sequences:

>Translated_377_residues
MSDGIVIIGSGFAARQLVKNIRKQDAQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLTLQSAGEFAEQYTLRLFPHTW
VSDIDAENRLVKSQDNQWRYDKLVLATGATPFIPSVPGRELMLTLNSQREYGAAQSRLHDAKRVLIVGGGLIGCELAMDF
CRAGKAVTVVDNSASVLAALMPPEASSRLQHRLTEMGVHLMLKTQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPE
TSLARHAGLQINRGIVVNSQLQTSDPAIYALGDCAEINGVVLPFLQPILLSAMCLSKNLLAQAGELKLPPMLVKVKTPDL
PLHLAGDTRRDDLTWNIVAAKEGLVAKGVDAENQLRAFVVSEDKMKEAFALLKQLVS
>Mature_376_residues
SDGIVIIGSGFAARQLVKNIRKQDAQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLTLQSAGEFAEQYTLRLFPHTWV
SDIDAENRLVKSQDNQWRYDKLVLATGATPFIPSVPGRELMLTLNSQREYGAAQSRLHDAKRVLIVGGGLIGCELAMDFC
RAGKAVTVVDNSASVLAALMPPEASSRLQHRLTEMGVHLMLKTQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPET
SLARHAGLQINRGIVVNSQLQTSDPAIYALGDCAEINGVVLPFLQPILLSAMCLSKNLLAQAGELKLPPMLVKVKTPDLP
LHLAGDTRRDDLTWNIVAAKEGLVAKGVDAENQLRAFVVSEDKMKEAFALLKQLVS

Specific function: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI226437568, Length=324, Percent_Identity=23.7654320987654, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI65787454, Length=324, Percent_Identity=23.7654320987654, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI21389617, Length=324, Percent_Identity=23.7654320987654, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI4757732, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI22202629, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1789065, Length=375, Percent_Identity=76.8, Blast_Score=599, Evalue=1e-173,
Organism=Escherichia coli, GI1788892, Length=280, Percent_Identity=28.9285714285714, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789765, Length=294, Percent_Identity=27.5510204081633, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787352, Length=247, Percent_Identity=31.1740890688259, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082354, Length=218, Percent_Identity=29.8165137614679, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559934, Length=275, Percent_Identity=26.5454545454545, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI32565766, Length=144, Percent_Identity=31.9444444444444, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358499, Length=142, Percent_Identity=30.9859154929577, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639257, Length=280, Percent_Identity=23.2142857142857, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 40913; Mature: 40782

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGIVIIGSGFAARQLVKNIRKQDAQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLT
CCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCC
LQSAGEFAEQYTLRLFPHTWVSDIDAENRLVKSQDNQWRYDKLVLATGATPFIPSVPGRE
HHHHHHHHHHHEEEECCCHHHHCCCCCCCEECCCCCCEEEEEEEEEECCCCCCCCCCCCE
LMLTLNSQREYGAAQSRLHDAKRVLIVGGGLIGCELAMDFCRAGKAVTVVDNSASVLAAL
EEEEECCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
MPPEASSRLQHRLTEMGVHLMLKTQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPE
CCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCEEEEECCCCEEEHHHHHHHCCCCCC
TSLARHAGLQINRGIVVNSQLQTSDPAIYALGDCAEINGVVLPFLQPILLSAMCLSKNLL
HHHHHHCCCEECCCEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQAGELKLPPMLVKVKTPDLPLHLAGDTRRDDLTWNIVAAKEGLVAKGVDAENQLRAFVV
HCCCCCCCCCEEEEEECCCCCEEECCCCCCCCEEEEEEEECCCCEECCCCCCCCEEEEEE
SEDKMKEAFALLKQLVS
CHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SDGIVIIGSGFAARQLVKNIRKQDAQIPLTLIAADSMDEYNKPDLSHVISRGQKADDLT
CCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCC
LQSAGEFAEQYTLRLFPHTWVSDIDAENRLVKSQDNQWRYDKLVLATGATPFIPSVPGRE
HHHHHHHHHHHEEEECCCHHHHCCCCCCCEECCCCCCEEEEEEEEEECCCCCCCCCCCCE
LMLTLNSQREYGAAQSRLHDAKRVLIVGGGLIGCELAMDFCRAGKAVTVVDNSASVLAAL
EEEEECCCCCCCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
MPPEASSRLQHRLTEMGVHLMLKTQLEGLEQTADGIRVSLDRQRAITVDAVVAAAGLRPE
CCCCHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCEEEEECCCCEEEHHHHHHHCCCCCC
TSLARHAGLQINRGIVVNSQLQTSDPAIYALGDCAEINGVVLPFLQPILLSAMCLSKNLL
HHHHHHCCCEECCCEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AQAGELKLPPMLVKVKTPDLPLHLAGDTRRDDLTWNIVAAKEGLVAKGVDAENQLRAFVV
HCCCCCCCCCEEEEEECCCCCEEECCCCCCCCEEEEEEEECCCCEECCCCCCCCEEEEEE
SEDKMKEAFALLKQLVS
CHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; oxidized flavorubredoxin; O2 [C]

Specific reaction: NADH + oxidized flavorubredoxin + O2 = NAD + reduced flavorubredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA