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The map label for this gene is srlR [H]

Identifier: 238896161

GI number: 238896161

Start: 4131920

End: 4132693

Strand: Direct

Name: srlR [H]

Synonym: KP1_4307

Alternate gene names: 238896161

Gene position: 4131920-4132693 (Clockwise)

Preceding gene: 238896160

Following gene: 238896162

Centisome position: 78.73

GC content: 53.75

Gene sequence:

>774_bases
ATGAAACCACGTCAGCGCCAGGCAGCCATTCTCGAGTTCCTGCAGTCGCAGGGAAAATGCTCGGTCGAAGAGCTGGCGCA
ACACTTCGATACCACTGGCACCACCATCCGCAAGGATCTGGTCACGCTGGAAAACGCCGGCACCGTCATTCGCACCTACG
GTGGCGTGGTACTCAACAAGGATGAAGCCGATCCGCCGATTGACCATAAGACGCTGATCAACACCCATAAAAAAGCCCAG
ATTGCCGAGGCCGCCGTGCGATACATCCACGATGGCGATTCAATTATCCTCGACGCCGGCAGCACCGTGCTGCAGATGGT
GCCATTGCTGAGTCACTTTAATAACATCACGGTGATGACCAACAGCCTGCATATCGTCAACGCGCTATCAGAGTTCGATA
ACGAGCAGACCATCCTGATGCCGGGCGGCACCTTCCGTAAAAAATCGGCCTCTTTTCACGGCCAGCTGGCGGAAAACGCC
TTCGAACAGTTCAGCTTCGACAAGCTGTTTATGGGCACCGACGGTATCGATCTGAACGCCGGAGTCACTACCTTTAATGA
GGTCTATACCGTCAGCAAAGCGATGTGCAACGCCGCCCGCGAAGTGATCCTGATGGCCGACTCATCCAAGTTTGGTCGTA
AAAGCCCCAATATTGTCTGCGGCCTTGAACGCGTGGATAAATTGATTACCGATGCCGATATTGACCCGGAATTCCAGCGG
GCGCTGGAAGCCAAAGGCATAGCAGTCATTATTACTGGAGAACATCATGAGTAA

Upstream 100 bases:

>100_bases
ACTATCATTAGCGCTTAATCCGAAACATGGATAATTTCGTTGTAAAAGTAAATATCTTGCGAAATTATCACTTCGAAACT
TAAACGCAGGATAGACGCCT

Downstream 100 bases:

>100_bases
CTTTTTGTTAGAGGCCGGACGCCAGACCCTGATGCTTGAGCTGCAGGAGGCGAGCCGCCTGCCGGAGCGCCTGGGCGACG
ACTTCATCCGCGCGGCGGAA

Product: DNA-binding transcriptional repressor SrlR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKPRQRQAAILEFLQSQGKCSVEELAQHFDTTGTTIRKDLVTLENAGTVIRTYGGVVLNKDEADPPIDHKTLINTHKKAQ
IAEAAVRYIHDGDSIILDAGSTVLQMVPLLSHFNNITVMTNSLHIVNALSEFDNEQTILMPGGTFRKKSASFHGQLAENA
FEQFSFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNIVCGLERVDKLITDADIDPEFQR
ALEAKGIAVIITGEHHE

Sequences:

>Translated_257_residues
MKPRQRQAAILEFLQSQGKCSVEELAQHFDTTGTTIRKDLVTLENAGTVIRTYGGVVLNKDEADPPIDHKTLINTHKKAQ
IAEAAVRYIHDGDSIILDAGSTVLQMVPLLSHFNNITVMTNSLHIVNALSEFDNEQTILMPGGTFRKKSASFHGQLAENA
FEQFSFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNIVCGLERVDKLITDADIDPEFQR
ALEAKGIAVIITGEHHE
>Mature_257_residues
MKPRQRQAAILEFLQSQGKCSVEELAQHFDTTGTTIRKDLVTLENAGTVIRTYGGVVLNKDEADPPIDHKTLINTHKKAQ
IAEAAVRYIHDGDSIILDAGSTVLQMVPLLSHFNNITVMTNSLHIVNALSEFDNEQTILMPGGTFRKKSASFHGQLAENA
FEQFSFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNIVCGLERVDKLITDADIDPEFQR
ALEAKGIAVIITGEHHE

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=89.8832684824903, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1789519, Length=254, Percent_Identity=35.4330708661417, Blast_Score=173, Evalue=8e-45,
Organism=Escherichia coli, GI1789829, Length=234, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=29.6442687747036, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788069, Length=241, Percent_Identity=30.2904564315353, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787540, Length=232, Percent_Identity=32.3275862068966, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082344, Length=255, Percent_Identity=27.4509803921569, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790753, Length=246, Percent_Identity=30.0813008130081, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=23.015873015873, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=28.3261802575107, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787063, Length=249, Percent_Identity=23.6947791164659, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28262; Mature: 28262

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRQRQAAILEFLQSQGKCSVEELAQHFDTTGTTIRKDLVTLENAGTVIRTYGGVVLNK
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEC
DEADPPIDHKTLINTHKKAQIAEAAVRYIHDGDSIILDAGSTVLQMVPLLSHFNNITVMT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEE
NSLHIVNALSEFDNEQTILMPGGTFRKKSASFHGQLAENAFEQFSFDKLFMGTDGIDLNA
CCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
GVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNIVCGLERVDKLITDADIDPEFQR
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEECHHHHHHHHHCCCCCHHHHH
ALEAKGIAVIITGEHHE
HHHHCCEEEEEECCCCC
>Mature Secondary Structure
MKPRQRQAAILEFLQSQGKCSVEELAQHFDTTGTTIRKDLVTLENAGTVIRTYGGVVLNK
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCEEEEC
DEADPPIDHKTLINTHKKAQIAEAAVRYIHDGDSIILDAGSTVLQMVPLLSHFNNITVMT
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCEEEEE
NSLHIVNALSEFDNEQTILMPGGTFRKKSASFHGQLAENAFEQFSFDKLFMGTDGIDLNA
CCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
GVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNIVCGLERVDKLITDADIDPEFQR
CCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEECHHHHHHHHHCCCCCHHHHH
ALEAKGIAVIITGEHHE
HHHHCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]