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The map label for this gene is proX [H]

Identifier: 238896134

GI number: 238896134

Start: 4105116

End: 4106114

Strand: Direct

Name: proX [H]

Synonym: KP1_4273

Alternate gene names: 238896134

Gene position: 4105116-4106114 (Clockwise)

Preceding gene: 238896133

Following gene: 238896135

Centisome position: 78.21

GC content: 57.86

Gene sequence:

>999_bases
ATGCGACATAGTACGATGTTGGCCACCGCCGCCTTTGCCACCCTGCTCGCCACCAGCGCCTTCGCCGCCGACCTGCCGGG
TAAAGGGATTACGGTGAAGCCCGCTCAGAGCACTATCTCCGAAGAGAGCTTCCAGACCCTGCTGGTCAGTCGCGCGCTGG
AGAAGCTGGGCTACACCGTCGAGAAACCCAGCGAAGTGGACTATAACGTTGCCTATACGTCGATTGCCGCCGGAGATACC
ACCTTTATCGCCACCAACTGGCAACCGCTGCACGATGACATGTACGCCGCGGCGGGCGGTGATAACAAATTCTATCGCAA
AGGAGTGTACGTCTCAGGCGCCGCCCAGGGCTATTTGATCGACAAAAAAACCGCTGAGCAGTACCACATAACCTCCATCG
ATCAGCTCAAAGATCCGCAGATCGCCAAACTGTTTGATACCAACAACGACGGTAAAGCGGATCTCACCGGCTGTACCCCA
GGATGGGGCTGCGAAGCAGTGATTAACCATCAGATTGACGCCTATGGCCTGAGCAAAACCGTCACCCATAACCAGGGCAA
CTACGCAGCGATGATGGCCGACACCATTGCCCGGTATAAAGAGGGTAAACCGGTGCTCTACTACACCTGGACGCCGTACT
GGGTTAGCGACGTGCTGAAGCCTGGCAAGGACGTCGTCTGGCTGCAGGTGCCGTTCTCCTCCCTGCCGGGCGAGCAGAAA
AACATCGACACCAAACTGGCCAACGGCGCCAACTATGGCTTCCCGGTGAACACCATGCACATCGTCGCCAACAAAGCCTG
GGCGGAGAAAAATCCGGCCGCCGCCACTCTGTTTAGCGTCATGAAGCTGCCGATCGCCGACATCAACGCCGAGAATGCGA
TGATGCACGAAGGCCATGCTTCCGAAGCCGACATTAACGGCCACGTTGATGGCTGGATCAAAGCCCACCAGCCGCTGTTC
GACAGCTGGGTGAAAACCGCCCTCGCCGCGCAGCAGTAA

Upstream 100 bases:

>100_bases
CCCGCTGGGGCTTATCACTCGCCCTTTCTGTCGATAAGTCGATAACAGCGCCGCTCCCCCCGGGAGCGGCCCTTCCCGTT
AAACAATAAGAGGAACCACC

Downstream 100 bases:

>100_bases
ACCCGCTCACGGATAAGGCCCAGCGCCTTATCCGGCCCCCTTGCCCCCCTTTCTCGTGGCCAGGTCATAGAAAAGCGATT
CCAGGAATTTCCATAGTGTT

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MRHSTMLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSEVDYNVAYTSIAAGDT
TFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTP
GWGCEAVINHQIDAYGLSKTVTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQK
NIDTKLANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADINGHVDGWIKAHQPLF
DSWVKTALAAQQ

Sequences:

>Translated_332_residues
MRHSTMLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSEVDYNVAYTSIAAGDT
TFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTP
GWGCEAVINHQIDAYGLSKTVTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQK
NIDTKLANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADINGHVDGWIKAHQPLF
DSWVKTALAAQQ
>Mature_332_residues
MRHSTMLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTVEKPSEVDYNVAYTSIAAGDT
TFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLIDKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTP
GWGCEAVINHQIDAYGLSKTVTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQK
NIDTKLANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHASEADINGHVDGWIKAHQPLF
DSWVKTALAAQQ

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=332, Percent_Identity=79.8192771084337, Blast_Score=560, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 36173; Mature: 36173

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSTMLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
EKPSEVDYNVAYTSIAAGDTTFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLI
CCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCEEECCCCCCEEECCEEEECCCCEEEE
DKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCEAVINHQIDAYGLSKT
ECCCCCEEECCCHHHCCCCCEEEEEECCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCEE
VTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQK
EECCCCCEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEEEEEECHHHCCCCCC
NIDTKLANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHA
CCCHHHCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCC
SEADINGHVDGWIKAHQPLFDSWVKTALAAQQ
CCCCCCCCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHSTMLATAAFATLLATSAFAADLPGKGITVKPAQSTISEESFQTLLVSRALEKLGYTV
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
EKPSEVDYNVAYTSIAAGDTTFIATNWQPLHDDMYAAAGGDNKFYRKGVYVSGAAQGYLI
CCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCEEECCCCCCEEECCEEEECCCCEEEE
DKKTAEQYHITSIDQLKDPQIAKLFDTNNDGKADLTGCTPGWGCEAVINHQIDAYGLSKT
ECCCCCEEECCCHHHCCCCCEEEEEECCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCEE
VTHNQGNYAAMMADTIARYKEGKPVLYYTWTPYWVSDVLKPGKDVVWLQVPFSSLPGEQK
EECCCCCEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCCCEEEEEECHHHCCCCCC
NIDTKLANGANYGFPVNTMHIVANKAWAEKNPAAATLFSVMKLPIADINAENAMMHEGHA
CCCHHHCCCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEECCCC
SEADINGHVDGWIKAHQPLFDSWVKTALAAQQ
CCCCCCCCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]