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The map label for this gene is aroF [H]

Identifier: 238896046

GI number: 238896046

Start: 4015325

End: 4016464

Strand: Reverse

Name: aroF [H]

Synonym: KP1_4178

Alternate gene names: 238896046

Gene position: 4016464-4015325 (Counterclockwise)

Preceding gene: 238896050

Following gene: 238896045

Centisome position: 76.53

GC content: 58.07

Gene sequence:

>1140_bases
GTGTGGTATCGTTACGTCATGCCCTCTGAGGCAACCCTTATCGCAAACGAGCTACACAGGATCGCAATCATGCAAAAAGA
CGCGCTGAACAACGTACATATTACCGACGAACATGTATTAATGACCCCGGAGCAACTGAAGGCGGAATTCCCGCTGAGCG
TCGAGCAGGAAGCGCAGATCGCGCACGCCCGTCAGACCATTTCGGATATCATCGCCGGTCGCGATCCGCGCCTGCTGGTG
GTATGTGGTCCTTGCTCCATTCACGATCCGGAAGCTGCGATTGAATATGCTCGTCGGTTTAAAGCCCTTGCCGCAGAGGT
CAGCGATAGCCTCTACCTGGTGATGCGCGTCTATTTTGAAAAACCCCGTACCACCGTCGGCTGGAAGGGGCTGATTAACG
ATCCGCACATGGATGGTTCGTTTGATGTTGAAGGCGGCCTGAAGATTGCGCGTCGTCTGCTGGTCGAGCTAGTCAATATG
GGACTGCCGCTGGCGACGGAAGCGCTGGATCCCAACAGCCCGCAGTACCTCGGGGATCTGTTCAGCTGGTCCGCTATCGG
CGCGCGTACCACGGAATCACAAACGCACCGCGAAATGGCCTCTGGCCTGTCGATGCCGGTCGGCTTTAAAAACGGTACCG
ACGGTAGCCTGGCCACGGCTATCAACGCCATGCGCGCCGCGGCGATGCCGCACCGTTTCGTCGGCATCAACCAGGCCGGG
CAGGTCTGCCTGCTGCAAACGCAGGGTAATCCGAACGGCCATGTGATCCTCCGCGGCGGCAAGGCGCCGAACTACGGTCC
GGAAGATGTGGCGAAATGCGAAAAAGAGATGGCGCAGGCGGGACTGAAGCCGTCGCTGATGGTAGATTGCAGTCATGGGA
ACTCCAATAAAGATTTCCGCCGCCAGCCGGCCGTGGCTGAATCCGTGGTCGCGCAGATCAAAGATGGCAACCGCTCCATT
ATCGGCCTGATGATCGAAAGTAATATCCACGAAGGCAATCAGTCCTCTGAACAGCCGCGTGAGGCGATGAAATACGGCGT
CTCGGTGACGGATGCCTGCATCAGCTGGGAGACTACCGAGGCGCTGCTGCGTGAACTGGATAAGGATCTCCGCGGCCACT
TGGCGGCCCGTTTGGTTTAA

Upstream 100 bases:

>100_bases
TATGTGTAAATATTGTTATACGCATCGCGCCATTGTGAGTGGCAATTAATTCGTTGGTGTAAATTAAAATTTACGGAATA
TGGATTGAATTCTTTACTTT

Downstream 100 bases:

>100_bases
GAGGAAAGTATGGTTGCTGAACTGACCGCGTTACGCGATCAAATTGATGAAGTGGATAAAGCGTTGCTTAGCCTGCTGGC
TAAGCGTCTGGAGCTGGTGG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MWYRYVMPSEATLIANELHRIAIMQKDALNNVHITDEHVLMTPEQLKAEFPLSVEQEAQIAHARQTISDIIAGRDPRLLV
VCGPCSIHDPEAAIEYARRFKALAAEVSDSLYLVMRVYFEKPRTTVGWKGLINDPHMDGSFDVEGGLKIARRLLVELVNM
GLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAMPHRFVGINQAG
QVCLLQTQGNPNGHVILRGGKAPNYGPEDVAKCEKEMAQAGLKPSLMVDCSHGNSNKDFRRQPAVAESVVAQIKDGNRSI
IGLMIESNIHEGNQSSEQPREAMKYGVSVTDACISWETTEALLRELDKDLRGHLAARLV

Sequences:

>Translated_379_residues
MWYRYVMPSEATLIANELHRIAIMQKDALNNVHITDEHVLMTPEQLKAEFPLSVEQEAQIAHARQTISDIIAGRDPRLLV
VCGPCSIHDPEAAIEYARRFKALAAEVSDSLYLVMRVYFEKPRTTVGWKGLINDPHMDGSFDVEGGLKIARRLLVELVNM
GLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAMPHRFVGINQAG
QVCLLQTQGNPNGHVILRGGKAPNYGPEDVAKCEKEMAQAGLKPSLMVDCSHGNSNKDFRRQPAVAESVVAQIKDGNRSI
IGLMIESNIHEGNQSSEQPREAMKYGVSVTDACISWETTEALLRELDKDLRGHLAARLV
>Mature_379_residues
MWYRYVMPSEATLIANELHRIAIMQKDALNNVHITDEHVLMTPEQLKAEFPLSVEQEAQIAHARQTISDIIAGRDPRLLV
VCGPCSIHDPEAAIEYARRFKALAAEVSDSLYLVMRVYFEKPRTTVGWKGLINDPHMDGSFDVEGGLKIARRLLVELVNM
GLPLATEALDPNSPQYLGDLFSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAMPHRFVGINQAG
QVCLLQTQGNPNGHVILRGGKAPNYGPEDVAKCEKEMAQAGLKPSLMVDCSHGNSNKDFRRQPAVAESVVAQIKDGNRSI
IGLMIESNIHEGNQSSEQPREAMKYGVSVTDACISWETTEALLRELDKDLRGHLAARLV

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=355, Percent_Identity=90.4225352112676, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1786969, Length=337, Percent_Identity=54.8961424332344, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1787996, Length=329, Percent_Identity=49.2401215805471, Blast_Score=333, Evalue=2e-92,
Organism=Saccharomyces cerevisiae, GI6320240, Length=344, Percent_Identity=51.7441860465116, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=51.1428571428571, Blast_Score=353, Evalue=3e-98,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 41578; Mature: 41578

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWYRYVMPSEATLIANELHRIAIMQKDALNNVHITDEHVLMTPEQLKAEFPLSVEQEAQI
CCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEECCCEEEECHHHHCCCCCCCCCHHHHH
AHARQTISDIIAGRDPRLLVVCGPCSIHDPEAAIEYARRFKALAAEVSDSLYLVMRVYFE
HHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
KPRTTVGWKGLINDPHMDGSFDVEGGLKIARRLLVELVNMGLPLATEALDPNSPQYLGDL
CCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHH
FSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAMPHRFVGINQAG
HHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCCC
QVCLLQTQGNPNGHVILRGGKAPNYGPEDVAKCEKEMAQAGLKPSLMVDCSHGNSNKDFR
CEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHH
RQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPREAMKYGVSVTDACISWETTE
HCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHCCHHHH
ALLRELDKDLRGHLAARLV
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWYRYVMPSEATLIANELHRIAIMQKDALNNVHITDEHVLMTPEQLKAEFPLSVEQEAQI
CCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEECCCEEEECHHHHCCCCCCCCCHHHHH
AHARQTISDIIAGRDPRLLVVCGPCSIHDPEAAIEYARRFKALAAEVSDSLYLVMRVYFE
HHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
KPRTTVGWKGLINDPHMDGSFDVEGGLKIARRLLVELVNMGLPLATEALDPNSPQYLGDL
CCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHH
FSWSAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAMPHRFVGINQAG
HHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHEECCCCCC
QVCLLQTQGNPNGHVILRGGKAPNYGPEDVAKCEKEMAQAGLKPSLMVDCSHGNSNKDFR
CEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHH
RQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPREAMKYGVSVTDACISWETTE
HCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHCCHHHH
ALLRELDKDLRGHLAARLV
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]