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The map label for this gene is engA [H]

Identifier: 238895966

GI number: 238895966

Start: 3919596

End: 3921074

Strand: Reverse

Name: engA [H]

Synonym: KP1_4091

Alternate gene names: 238895966

Gene position: 3921074-3919596 (Counterclockwise)

Preceding gene: 238895967

Following gene: 238895965

Centisome position: 74.71

GC content: 58.15

Gene sequence:

>1479_bases
ATGATACCTGTGGTCGCGCTTGTCGGGCGCCCTAACGTTGGAAAATCCACGCTCTTTAACCGCCTGACGCGCACTCGTGA
TGCGCTGGTTGCGGATTTCCCGGGGCTGACTCGTGACCGTAAGTACGGTCGGGCCGAAGTCGAAGGCCGCGAATTCATCT
GTATCGATACCGGTGGTATTGATGGTACGGAAGAGGGCGTGGAAACCCGGATGGCGGAGCAGTCGCTGCTGGCAATCGAA
GAGGCCGATGTGGTGCTGTTTATGGTCGATGCGCGCGCGGGCCTGATGCCGGCGGACATCGCGATCGCTAAACACCTGCG
CTCTCGTGAAAAGCCCACCTTCCTGGTGGCTAACAAAACCGACGGCATCGACGTCGACCAGGCGATGGCGGACTTCTGGT
CGCTCGGCCTGGGCGATATCTATCCGATTGCCGCTTCGCACGGCCGCGGCGTGACCAGCCTGCTGGAGCAGGCCCTGCTG
CCATGGGTAGATGAGGTTAATCCGCAGGAAGAGGTGGATGAAGATGCCGAATACTGGGCGAAATTCGAAGCCGAGCAGAA
TGGCGAAGCGGAAGAAGAGCCGGAAGACGACTTCAATCCGCAGGATCTGCCGATCAAGCTGGCGATTGTCGGGCGTCCTA
ATGTCGGTAAATCAACCCTCACCAATCGCATCCTCGGTGAAGATCGCGTGGTGGTCTACGATATGCCGGGCACCACCCGT
GACAGCATTTATATCCCGATGCAGCGTGACGAGCGCGAATACGTGCTCATCGATACCGCTGGGGTGCGCAAGCGCGGGAA
AATCACCGACGTCGTGGAAAAGTTCTCGGTGATCAAAACGCTGCAGGCGATTGAAGACGCCAACGTCGTGCTGCTGGTGA
TCGATGCTCGCGAAGGGATCTCCGACCAGGACCTCTCGCTGCTGGGCTTTATTCTTAACAGCGGCCGTTCGCTGGTGATC
GTCGTTAACAAGTGGGATGGCCTGAGTCAGGAAGTGAAGGAGCAGGTGAAGGAGACCCTCGACTATCGTCTGGGCTTTAT
CGACTTTGCCCGGGTGCACTTCATCTCCGCCCTGCACGGCAGCGGCGTCGGCAACCTGTTTGAATCGGTACGCGAAGCCT
ACGACAGCGCTACGCGCCGCGTAAGCACCGCGATGCTGACCCGGATCATGAACATGGCGGCGGAAGATCATCAGCCACCG
CTGGTGCGTGGCCGTCGCGTGAAGCTGAAATACGCCCACGCCGGGGGCTACAACCCGCCTATCGTGGTGATCCACGGTAA
CCAGGTCAAGGATCTGCCGGATTCCTACAAGCGCTATCTGATGAACTACTTCCGTAAATCCCTGGACGTGATGGGCACGC
CAATCCGTATCCAGTTCAAGGAAGGGGAAAACCCGTTCGCTAACAAGCGTAACACCCTGACGCCGAACCAGATGCGTAAA
CGTAAGCGCTTGATCAAGCACATCAAGAAAAGCAAATAA

Upstream 100 bases:

>100_bases
GAGTGATTAAGAAACGGCCCCTGGCAGACAGGGGCCGTTTTGACTTTTTTAAAAACGTCGTTAAGACGATGTTGCTTAGT
GATTGTATGAGGCATTTAAC

Downstream 100 bases:

>100_bases
TCATTAAACCCGCTTCGGCGGGTTTTTTGTGGCCGCCATGCCGGTAAATGTCAAAACCTTCCGCCATAATCCCGCGATAC
TTCGCCGGGAACAGAGCGGC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEEGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADIAIAKHLRSREKPTFLVANKTDGIDVDQAMADFWSLGLGDIYPIAASHGRGVTSLLEQALL
PWVDEVNPQEEVDEDAEYWAKFEAEQNGEAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTR
DSIYIPMQRDEREYVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVI
VVNKWDGLSQEVKEQVKETLDYRLGFIDFARVHFISALHGSGVGNLFESVREAYDSATRRVSTAMLTRIMNMAAEDHQPP
LVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPFANKRNTLTPNQMRK
RKRLIKHIKKSK

Sequences:

>Translated_492_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEEGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADIAIAKHLRSREKPTFLVANKTDGIDVDQAMADFWSLGLGDIYPIAASHGRGVTSLLEQALL
PWVDEVNPQEEVDEDAEYWAKFEAEQNGEAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTR
DSIYIPMQRDEREYVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVI
VVNKWDGLSQEVKEQVKETLDYRLGFIDFARVHFISALHGSGVGNLFESVREAYDSATRRVSTAMLTRIMNMAAEDHQPP
LVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPFANKRNTLTPNQMRK
RKRLIKHIKKSK
>Mature_492_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGIDGTEEGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADIAIAKHLRSREKPTFLVANKTDGIDVDQAMADFWSLGLGDIYPIAASHGRGVTSLLEQALL
PWVDEVNPQEEVDEDAEYWAKFEAEQNGEAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTR
DSIYIPMQRDEREYVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVI
VVNKWDGLSQEVKEQVKETLDYRLGFIDFARVHFISALHGSGVGNLFESVREAYDSATRRVSTAMLTRIMNMAAEDHQPP
LVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPFANKRNTLTPNQMRK
RKRLIKHIKKSK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=492, Percent_Identity=91.6666666666667, Blast_Score=908, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=39.1304347826087, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=125, Percent_Identity=32.8, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=31.9444444444444, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 55224; Mature: 55224

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
DGTEEGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADIAIAKHLRSREKPTFLVANKT
CCCHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCC
DGIDVDQAMADFWSLGLGDIYPIAASHGRGVTSLLEQALLPWVDEVNPQEEVDEDAEYWA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHCHHHHHHH
KFEAEQNGEAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTR
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCC
DSIYIPMQRDEREYVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGI
CCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDYRLGFIDFARVHFISALHG
CCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
SGVGNLFESVREAYDSATRRVSTAMLTRIMNMAAEDHQPPLVRGRRVKLKYAHAGGYNPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCC
IVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPFANKRNTLTPNQMRK
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RKRLIKHIKKSK
HHHHHHHHHCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEVEGREFICIDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
DGTEEGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADIAIAKHLRSREKPTFLVANKT
CCCHHHHHHHHHHHHHHEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCC
DGIDVDQAMADFWSLGLGDIYPIAASHGRGVTSLLEQALLPWVDEVNPQEEVDEDAEYWA
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHCHHHHHHH
KFEAEQNGEAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPGTTR
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCC
DSIYIPMQRDEREYVLIDTAGVRKRGKITDVVEKFSVIKTLQAIEDANVVLLVIDAREGI
CCEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQVKETLDYRLGFIDFARVHFISALHG
CCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
SGVGNLFESVREAYDSATRRVSTAMLTRIMNMAAEDHQPPLVRGRRVKLKYAHAGGYNPP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCC
IVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGTPIRIQFKEGENPFANKRNTLTPNQMRK
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHH
RKRLIKHIKKSK
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA