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The map label for this gene is yfcH [H]

Identifier: 238895823

GI number: 238895823

Start: 3768660

End: 3769553

Strand: Direct

Name: yfcH [H]

Synonym: KP1_3940

Alternate gene names: 238895823

Gene position: 3768660-3769553 (Clockwise)

Preceding gene: 238895822

Following gene: 238895824

Centisome position: 71.8

GC content: 61.74

Gene sequence:

>894_bases
ATGAAGATCCTGCTTACTGGTGGTACCGGCCTGATTGGCCGACATCTGATACCCAGATTGCTGGAGCTCGGGCATAGCGT
CACGGTCTCCACGCGACATCCGGATACCGCCCGCGCCCGTCTCGATCCGCGCGTCACCCTGTGGCGCGATTTCGAGGGCC
ATCACCACCTCAATAATATTGATGCCGTCATCAATCTGGCGGGTGAACCCATCGCTGATAAACGCTGGACGGCCGAGCAG
AAACAACGCTTGTGCCATAGCCGCTGGGATCTCACGCAGCGGCTGGTGGGCCTGATCCACGCCAGCGACACCCCTCCCTC
CGTGCTGATCAGCGGGTCTGCCATCGGCTACTATGGCGACCTCGGCGAGGTGGTGGTGACCGAAGAAGAGCCACCGCACA
ATGAGTTTACCCATAAGCTGTGCGCCCGCTGGGAGCAAATTGCCTGCGAAGCGCAAAGCGAGCGCACCCGCGTCTGCCTG
CTGCGCACCGGCGTGGTACTGGCTCCGCGGGGCGGTATTCTCGGCAAAATGACACCCGCCTTTAAGCTCGGCCTCGGCGG
GCCTATCGGCAACGGCAGACAGTACCTGGCCTGGATCCATATCGACGATATGGTTAACGGCATTCTGTGGCTGCTGGATA
ACGATCTGCGCGGTCCGTTCAATATGGTTTCTCCCTACCCGGTGCATAACGAGCAGTTCGCCCATGCACTGGGTCATGCG
CTCCATCGACCGGCGATTTTCCGCGTTCCCGCCGCCGCTATCCGCCTGTTGATGGGGGAATCCGCCGTCCTGGTGCTCGG
CGGCCAGCGCGCGCTGCCAAAGCGTCTGGAGGCCGCCGGCTTCGCCTTCCGCTGGTACGATCTGGACGAAGCGCTAAAGG
ATGTGCTGAGTTAA

Upstream 100 bases:

>100_bases
ATATGCTGAAGTGGAGATTGATAAACTTCATGCGCTGCGCTATGCCGACTCGGTGTCCATGACCATGAGCTGGCGTCGCT
AACTATGTCAGGGAGGTGGT

Downstream 100 bases:

>100_bases
TGGCTGACACAGGGGAGCATTGGCTCCCCTGATTCCATTCTGCTGGCTCATGCTCCACGCCTTGATGGCCTCACCCTGGC
GCTGCAGCATCGCCATATTC

Product: NAD dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKILLTGGTGLIGRHLIPRLLELGHSVTVSTRHPDTARARLDPRVTLWRDFEGHHHLNNIDAVINLAGEPIADKRWTAEQ
KQRLCHSRWDLTQRLVGLIHASDTPPSVLISGSAIGYYGDLGEVVVTEEEPPHNEFTHKLCARWEQIACEAQSERTRVCL
LRTGVVLAPRGGILGKMTPAFKLGLGGPIGNGRQYLAWIHIDDMVNGILWLLDNDLRGPFNMVSPYPVHNEQFAHALGHA
LHRPAIFRVPAAAIRLLMGESAVLVLGGQRALPKRLEAAGFAFRWYDLDEALKDVLS

Sequences:

>Translated_297_residues
MKILLTGGTGLIGRHLIPRLLELGHSVTVSTRHPDTARARLDPRVTLWRDFEGHHHLNNIDAVINLAGEPIADKRWTAEQ
KQRLCHSRWDLTQRLVGLIHASDTPPSVLISGSAIGYYGDLGEVVVTEEEPPHNEFTHKLCARWEQIACEAQSERTRVCL
LRTGVVLAPRGGILGKMTPAFKLGLGGPIGNGRQYLAWIHIDDMVNGILWLLDNDLRGPFNMVSPYPVHNEQFAHALGHA
LHRPAIFRVPAAAIRLLMGESAVLVLGGQRALPKRLEAAGFAFRWYDLDEALKDVLS
>Mature_297_residues
MKILLTGGTGLIGRHLIPRLLELGHSVTVSTRHPDTARARLDPRVTLWRDFEGHHHLNNIDAVINLAGEPIADKRWTAEQ
KQRLCHSRWDLTQRLVGLIHASDTPPSVLISGSAIGYYGDLGEVVVTEEEPPHNEFTHKLCARWEQIACEAQSERTRVCL
LRTGVVLAPRGGILGKMTPAFKLGLGGPIGNGRQYLAWIHIDDMVNGILWLLDNDLRGPFNMVSPYPVHNEQFAHALGHA
LHRPAIFRVPAAAIRLLMGESAVLVLGGQRALPKRLEAAGFAFRWYDLDEALKDVLS

Specific function: Unknown

COG id: COG1090

COG function: function code R; Predicted nucleoside-diphosphate sugar epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. SDR39U1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116812630, Length=303, Percent_Identity=34.983498349835, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1788642, Length=296, Percent_Identity=83.1081081081081, Blast_Score=512, Evalue=1e-146,
Organism=Drosophila melanogaster, GI28573846, Length=296, Percent_Identity=31.7567567567568, Blast_Score=164, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013549
- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR010099 [H]

Pfam domain/function: PF08338 DUF1731; PF01370 Epimerase [H]

EC number: NA

Molecular weight: Translated: 32933; Mature: 32933

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLTGGTGLIGRHLIPRLLELGHSVTVSTRHPDTARARLDPRVTLWRDFEGHHHLNNI
CEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCEEEEECCCCCCCCCCH
DAVINLAGEPIADKRWTAEQKQRLCHSRWDLTQRLVGLIHASDTPPSVLISGSAIGYYGD
HHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCC
LGEVVVTEEEPPHNEFTHKLCARWEQIACEAQSERTRVCLLRTGVVLAPRGGILGKMTPA
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCCCCC
FKLGLGGPIGNGRQYLAWIHIDDMVNGILWLLDNDLRGPFNMVSPYPVHNEQFAHALGHA
EEECCCCCCCCCCEEEEEEEHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAIFRVPAAAIRLLMGESAVLVLGGQRALPKRLEAAGFAFRWYDLDEALKDVLS
HHCCEEEECCHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCEEEEECHHHHHHHHHC
>Mature Secondary Structure
MKILLTGGTGLIGRHLIPRLLELGHSVTVSTRHPDTARARLDPRVTLWRDFEGHHHLNNI
CEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCEEEEECCCCCCCCCCH
DAVINLAGEPIADKRWTAEQKQRLCHSRWDLTQRLVGLIHASDTPPSVLISGSAIGYYGD
HHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEECCC
LGEVVVTEEEPPHNEFTHKLCARWEQIACEAQSERTRVCLLRTGVVLAPRGGILGKMTPA
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCCCCCCCCCCC
FKLGLGGPIGNGRQYLAWIHIDDMVNGILWLLDNDLRGPFNMVSPYPVHNEQFAHALGHA
EEECCCCCCCCCCEEEEEEEHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAIFRVPAAAIRLLMGESAVLVLGGQRALPKRLEAAGFAFRWYDLDEALKDVLS
HHCCEEEECCHHHHHHHHCCCEEEEECCCCCCHHHHHHCCCEEEEECHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]