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The map label for this gene is nuoN [H]

Identifier: 238895793

GI number: 238895793

Start: 3738526

End: 3739983

Strand: Reverse

Name: nuoN [H]

Synonym: KP1_3908

Alternate gene names: 238895793

Gene position: 3739983-3738526 (Counterclockwise)

Preceding gene: 238895794

Following gene: 238895791

Centisome position: 71.26

GC content: 61.18

Gene sequence:

>1458_bases
ATGACAATAACTCCACAACAACTGATCGCACTGCTACCGCTGCTGATCGTCGGCTTGACGGTGGTGGTTGTGATGCTCTC
CATTGCGTGGCGACGCAATCATTTTCTCAATGCCACGCTGTCGGTTCTTGGACTTAACGCCGCGCTGGTCTCGCTCTGGT
TCGTCGGCCAGAACGGGGCGATGGACGTCACGCCGCTGATCCGCGTTGACGGCTACGCCATGCTTTACACCGGTCTGGTG
CTGCTGGCGAGCCTCGCGACCTGTACTTTCGCCTACCCGTGGCTTGAGGGTTACAAGGACAACAAAGAAGAGTTCTACCT
GCTGGTGCTGATCGCCGCCCTGGGCGGCATTCTGCTGGCCGGTGCGAATCATCTGGCGGCGCTGTTCCTCGGTATTGAGC
TGATTTCGCTGCCGCTGTTCGGCCTGGTTGGTTACGCCTTCCGCCAGAAGCGTTCGCTGGAAGCGAGCATCAAATACACC
ATCCTCTCCGCGGCAGCTTCGTCCTTCCTGCTGTTCGGTATGGCGCTGGTGTATGCGAACTCCGGCAACCTGTCCTTCCT
CGCGCTGGGCAAAAGCCTGGCGGACAACATGCTGCACGAGCCGCTGCTGCTGGCGGGCCTCGGTCTGATGATCGTCGGTC
TTGGCTTTAAACTGTCGCTGGTGCCGTTCCACCTGTGGACGCCGGACGTTTACCAGGGGGCGCCTGCGCCGGTCTCCACC
TTCCTGGCGACCGCCAGCAAGATCGCTATCTTCGGCGTAGTGATGCGTCTGTTCCTGTACATGCCGGTGGGCAACAGCGA
AGCGGTACGCGTGGTGCTGGGCCTGATCGCCTTCGCCTCTATCATCTTCGGTAACCTGATGGCGCTGAGCCAGACCAACA
TTAAGCGCCTGCTCGGTTACTCTTCCATCTCCCATCTCGGCTATCTGCTGGTGGCGCTGATTGCCCTGCAGAGCGGTGAA
ATGTCGATGGAAGCCGTGGGCGTTTACCTGGCCGGTTACCTGTTCAGCAGCCTCGGCGCGTTCGGCGTGGTCAGCCTGAT
GTCCAGCCCGTACCGCGGTCCGGATGCTGACTCGCTGTTCTCCTACCGCGGCCTGTTCTGGCACCGTCCGATCCTGTCGG
CTGTGATGACGGTGATGATGCTCTCCCTGGCCGGTATCCCGATGACCCTCGGCTTTATCGGTAAGTTCTACGTGCTGGCC
GTCGGTGTGCATGCGCATCTGTGGTGGCTGGTTGCCGCGGTGGTTGTCGGCTCGGCGATCGGTCTCTACTACTACCTGCG
CGTGGCAGTGAGCCTGTACCTGAGCGCGCCGGAGCAACTGAATCGCGATGCGCCGTCAAACTGGCAGTACAGCGCCGGCG
GTATCGTGGTGCTGATCTCCGCGCTGCTGGTGCTGGTGCTCGGTATCTGGCCGCAGCCGCTGATTAGCATCGTGCAGCTG
GCGACGCCGCTGATGTAA

Upstream 100 bases:

>100_bases
CTTCTTCCCGCAGCCGATCCTCGACACCTCGCATGCTGCGATGAGCAACATTCAGCAGTGGTTTGTTAATTCTGTTTCTA
CTACAAGGCCGTAATTCGCC

Downstream 100 bases:

>100_bases
GTTGATTGACTCAATAAAAAACCGCCGGGATGGCGGTTTTTTTATGCCCGGATTTTACGCCATCTTGTAGACCATAAAGT
CTTCCGCCAGCAGCGTGTTA

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVLGLNAALVSLWFVGQNGAMDVTPLIRVDGYAMLYTGLV
LLASLATCTFAYPWLEGYKDNKEEFYLLVLIAALGGILLAGANHLAALFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
ILSAAASSFLLFGMALVYANSGNLSFLALGKSLADNMLHEPLLLAGLGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVST
FLATASKIAIFGVVMRLFLYMPVGNSEAVRVVLGLIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGE
MSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILSAVMTVMMLSLAGIPMTLGFIGKFYVLA
VGVHAHLWWLVAAVVVGSAIGLYYYLRVAVSLYLSAPEQLNRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVQL
ATPLM

Sequences:

>Translated_485_residues
MTITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVLGLNAALVSLWFVGQNGAMDVTPLIRVDGYAMLYTGLV
LLASLATCTFAYPWLEGYKDNKEEFYLLVLIAALGGILLAGANHLAALFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
ILSAAASSFLLFGMALVYANSGNLSFLALGKSLADNMLHEPLLLAGLGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVST
FLATASKIAIFGVVMRLFLYMPVGNSEAVRVVLGLIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGE
MSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILSAVMTVMMLSLAGIPMTLGFIGKFYVLA
VGVHAHLWWLVAAVVVGSAIGLYYYLRVAVSLYLSAPEQLNRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVQL
ATPLM
>Mature_484_residues
TITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVLGLNAALVSLWFVGQNGAMDVTPLIRVDGYAMLYTGLVL
LASLATCTFAYPWLEGYKDNKEEFYLLVLIAALGGILLAGANHLAALFLGIELISLPLFGLVGYAFRQKRSLEASIKYTI
LSAAASSFLLFGMALVYANSGNLSFLALGKSLADNMLHEPLLLAGLGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTF
LATASKIAIFGVVMRLFLYMPVGNSEAVRVVLGLIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEM
SMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILSAVMTVMMLSLAGIPMTLGFIGKFYVLAV
GVHAHLWWLVAAVVVGSAIGLYYYLRVAVSLYLSAPEQLNRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVQLA
TPLM

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831108, Length=343, Percent_Identity=21.865889212828, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI251831117, Length=408, Percent_Identity=19.3627450980392, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI145693160, Length=485, Percent_Identity=93.4020618556701, Blast_Score=886, Evalue=0.0,
Organism=Escherichia coli, GI1788831, Length=205, Percent_Identity=32.1951219512195, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788829, Length=353, Percent_Identity=24.0793201133144, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788613, Length=350, Percent_Identity=26.2857142857143, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788614, Length=394, Percent_Identity=25.6345177664975, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52122; Mature: 51991

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVLGLNAALVSLWFVGQNGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
MDVTPLIRVDGYAMLYTGLVLLASLATCTFAYPWLEGYKDNKEEFYLLVLIAALGGILLA
CCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GANHLAALFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGNLSFLALGKSLADNMLHEPLLLAGLGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVST
CCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCCCHHHH
FLATASKIAIFGVVMRLFLYMPVGNSEAVRVVLGLIAFASIIFGNLMALSQTNIKRLLGY
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYRGLFWHRPILSAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVHAHLWWLVAAVVVGSAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLYYYLRVAVSLYLSAPEQLNRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVQL
HHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ATPLM
HCCCC
>Mature Secondary Structure 
TITPQQLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVLGLNAALVSLWFVGQNGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
MDVTPLIRVDGYAMLYTGLVLLASLATCTFAYPWLEGYKDNKEEFYLLVLIAALGGILLA
CCCCHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GANHLAALFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SGNLSFLALGKSLADNMLHEPLLLAGLGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVST
CCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCCCHHHH
FLATASKIAIFGVVMRLFLYMPVGNSEAVRVVLGLIAFASIIFGNLMALSQTNIKRLLGY
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSISHLGYLLVALIALQSGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SYRGLFWHRPILSAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVHAHLWWLVAAVVVGSAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLYYYLRVAVSLYLSAPEQLNRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVQL
HHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
ATPLM
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA