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The map label for this gene is elaC [H]

Identifier: 238895792

GI number: 238895792

Start: 3737551

End: 3738471

Strand: Direct

Name: elaC [H]

Synonym: KP1_3907

Alternate gene names: 238895792

Gene position: 3737551-3738471 (Clockwise)

Preceding gene: 238895784

Following gene: 238895806

Centisome position: 71.21

GC content: 60.59

Gene sequence:

>921_bases
ATGGAATTAACTTTTTTGGGGACATCCGCCGGGGTGCCGACCCGCACGCGTAATATGACGTCGATAATACTGAATTTGCA
ACAGCCGACCCGCGCTGAAATGTGGTTGTTTGACTGCGGCGAAGGGACCCAGCATCAGTTTCTTCACACGCCCTACCATC
CCGGCAAACTGAATAAGATTTTTATTACCCATCTGCACGGCGACCACCTGTTCGGCCTGCCCGGTCTGCTGTGCAGCCGC
TCGATGCAGGGAAACTCTCTGCCCCTCACCCTCTACGGGCCAAAAGGACTCAAAGAGTTTGTTGAGACCGCGCTGCGCCT
GAGCGGTTCGTGGACCGACTATCCGCTCACCATCATCGAAGTCGGCCCTGGTCTGGTGTTCGACGAAGAGGGCTATCGGG
TCACCGCGTATCCGCTCAGCCATCCGGTGGAGTGCTATGGGTATCGCATTGCGCAGCATGACAAGCCCGGCACCCTCGAC
GCCGCCCAGCTGATTGCCGATGGCGTGCCTCCCGGGCCGCTGTTCCATCAACTCAAGCGCGGACAGCGCGTCGAGCTGGC
AGATGGCCGGGTCATCGACGGCAGCCGCTATCTGGGGCCAGCGACCCCGGGTAAAACGCTGGCCATCTTCGGCGATACCG
CCCCCTGCCCGCAGGCGCTGGAGATGGCTCGCGGGGCGGATGTAATGGTCCACGAAACCACCCTTGAGCAGGCGATGGCG
GAGAAAGCCAATAGCCGCGGCCACTCTTCCAGTCAGCAGACCGCGGCGCTTGCCAAAGAAGCGGGGGTCGGTACGCTGAT
CGCCACCCACTTTAGCTCGCGCTACGATGCCGAAGGCTGTCTGCGTATGCTGGCGGAATGCCGGGAGATTTTCCCTAACA
CGCTGCTGGCGGAAGACTTTATGGTCTACAAGATGGCGTAA

Upstream 100 bases:

>100_bases
GAACGGTGAGTTCACTATGGTGGAGATCCTGCCAGGTCATCATCTGCTGCTCCTTATTGATATACTGATACTTTGCGACT
CGCCCTGAGGACACTGGACG

Downstream 100 bases:

>100_bases
AATCCGGGCATAAAAAAACCGCCATCCCGGCGGTTTTTTATTGAGTCAATCAACTTACATCAGCGGCGTCGCCAGCTGCA
CGATGCTAATCAGCGGCTGC

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MELTFLGTSAGVPTRTRNMTSIILNLQQPTRAEMWLFDCGEGTQHQFLHTPYHPGKLNKIFITHLHGDHLFGLPGLLCSR
SMQGNSLPLTLYGPKGLKEFVETALRLSGSWTDYPLTIIEVGPGLVFDEEGYRVTAYPLSHPVECYGYRIAQHDKPGTLD
AAQLIADGVPPGPLFHQLKRGQRVELADGRVIDGSRYLGPATPGKTLAIFGDTAPCPQALEMARGADVMVHETTLEQAMA
EKANSRGHSSSQQTAALAKEAGVGTLIATHFSSRYDAEGCLRMLAECREIFPNTLLAEDFMVYKMA

Sequences:

>Translated_306_residues
MELTFLGTSAGVPTRTRNMTSIILNLQQPTRAEMWLFDCGEGTQHQFLHTPYHPGKLNKIFITHLHGDHLFGLPGLLCSR
SMQGNSLPLTLYGPKGLKEFVETALRLSGSWTDYPLTIIEVGPGLVFDEEGYRVTAYPLSHPVECYGYRIAQHDKPGTLD
AAQLIADGVPPGPLFHQLKRGQRVELADGRVIDGSRYLGPATPGKTLAIFGDTAPCPQALEMARGADVMVHETTLEQAMA
EKANSRGHSSSQQTAALAKEAGVGTLIATHFSSRYDAEGCLRMLAECREIFPNTLLAEDFMVYKMA
>Mature_306_residues
MELTFLGTSAGVPTRTRNMTSIILNLQQPTRAEMWLFDCGEGTQHQFLHTPYHPGKLNKIFITHLHGDHLFGLPGLLCSR
SMQGNSLPLTLYGPKGLKEFVETALRLSGSWTDYPLTIIEVGPGLVFDEEGYRVTAYPLSHPVECYGYRIAQHDKPGTLD
AAQLIADGVPPGPLFHQLKRGQRVELADGRVIDGSRYLGPATPGKTLAIFGDTAPCPQALEMARGADVMVHETTLEQAMA
EKANSRGHSSSQQTAALAKEAGVGTLIATHFSSRYDAEGCLRMLAECREIFPNTLLAEDFMVYKMA

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

Organism=Homo sapiens, GI8922122, Length=361, Percent_Identity=34.0720221606648, Blast_Score=206, Evalue=2e-53,
Organism=Escherichia coli, GI87082078, Length=305, Percent_Identity=67.8688524590164, Blast_Score=446, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 33472; Mature: 33472

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTFLGTSAGVPTRTRNMTSIILNLQQPTRAEMWLFDCGEGTQHQFLHTPYHPGKLNKI
CEEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCEE
FITHLHGDHLFGLPGLLCSRSMQGNSLPLTLYGPKGLKEFVETALRLSGSWTDYPLTIIE
EEEEECCCCCCCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEE
VGPGLVFDEEGYRVTAYPLSHPVECYGYRIAQHDKPGTLDAAQLIADGVPPGPLFHQLKR
ECCCEEECCCCCEEEEECCCCCHHHHEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHC
GQRVELADGRVIDGSRYLGPATPGKTLAIFGDTAPCPQALEMARGADVMVHETTLEQAMA
CCEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHH
EKANSRGHSSSQQTAALAKEAGVGTLIATHFSSRYDAEGCLRMLAECREIFPNTLLAEDF
HHHHCCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCE
MVYKMA
EEEEEC
>Mature Secondary Structure
MELTFLGTSAGVPTRTRNMTSIILNLQQPTRAEMWLFDCGEGTQHQFLHTPYHPGKLNKI
CEEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEECCCCCCCCCEE
FITHLHGDHLFGLPGLLCSRSMQGNSLPLTLYGPKGLKEFVETALRLSGSWTDYPLTIIE
EEEEECCCCCCCCCHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEE
VGPGLVFDEEGYRVTAYPLSHPVECYGYRIAQHDKPGTLDAAQLIADGVPPGPLFHQLKR
ECCCEEECCCCCEEEEECCCCCHHHHEEEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHC
GQRVELADGRVIDGSRYLGPATPGKTLAIFGDTAPCPQALEMARGADVMVHETTLEQAMA
CCEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHH
EKANSRGHSSSQQTAALAKEAGVGTLIATHFSSRYDAEGCLRMLAECREIFPNTLLAEDF
HHHHCCCCCCHHHHHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCE
MVYKMA
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA