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The map label for this gene is uxuA [H]

Identifier: 238895730

GI number: 238895730

Start: 3662233

End: 3663423

Strand: Reverse

Name: uxuA [H]

Synonym: KP1_3833

Alternate gene names: 238895730

Gene position: 3663423-3662233 (Counterclockwise)

Preceding gene: 238895741

Following gene: 238895728

Centisome position: 69.8

GC content: 58.19

Gene sequence:

>1191_bases
ATGGAGCAAACCTGGCGGTGGTATGGGCCGAACGATCCGGTATCGCTTGATGATGTACGGCAGGCGGGGGCGACCGGCGT
CGTCACTGCGCTGCACCATATTGCAAACGGTCAGGTATGGCCGGTCGACGAGATTAAAGCGCGTCAGGCGCTGTTAGCGG
CAAAAGGGTTGACCTGGTCGGTCGTCGAAAGCATTCCCGTCCACGAGGATATTAAAACCCACAGCGGGCAGTATGCGACC
TGGATTGCCAACTATCAGCAGAGCATCCGCAACCTCGCGGCCTGCGGCATCGATACCGTGTGCTACAACTTTATGCCGAT
CCTCGACTGGACGCGCACCGATCTGGAATATGAGCTGCCGGACGGCTCCCGGGCGCTGCGTTTCGATCAGATCGCTTTCG
CCGCCTTTGAGCTGCATATCCTTAAACGCCCGGGTGCGGAAGCGGATTACAGTGAAGAAGAGCAGCGTCAGGCTGAGGTC
TATCTCAAGGCTATGAGCGAAGCAGATATCGATAAACTGACCCGCAATATCATCGCCGGCCTGCCGGGAGCGGAAGAGGG
CTACACCCTTGACCAGTTCCGCGCGCGTCTGGCGGAGTACGACCACATTGATAAAGCGCAGCTGCGTGAAAATATGGCCT
ATTTCCTGCGCGCCATCGTGCCGGTGTGCGAAGAGGTAGGGATCCGCCTGGCTGTGCATCCGGACGATCCGCCGCGGCCG
ATCCTTGGCCTGCCGCGTATCGTGTCGACCATCGAAGATATGCAGTGGCTGAAGGAGACGGTGGACAGCATTAATAATGG
CTTCACCATGTGTACCGGATCGTATGGCGTTCGCGCCGATAACGATCTGGTGAAGATGGTGGAGACCTTTGGCGATCGCA
TCCATTTTACCCATCTGCGCTCTACCTGCCGTGAAGCAAACCCAAAAACCTTCCACGAGGCGGCGCACCTTAGCGGCGAC
GTCAATATGGTGGCGGTGGTGGATGCTATCCTGCGTGAAGAGCAGCGGCGTAAACAGGCCGGCGATCTGCGCCCGATCCC
ATTTCGGCCGGATCATGGTCATCAGATGCTCGACGATCTGCGCAAGAAAACCAACCCAGGCTATTCGGCGATTGGCCGTC
TCAAGGGGATGGCGGAAGTGCGCGGCGTCGAGCTGGCGCTGAAAATGACCAAATACCCTGAACTGCTGTAA

Upstream 100 bases:

>100_bases
TCAATAGGCCAGCACTGTTTGCAGCCAGGTGAGAAACATGTATGGTAGTCGTCATGAGTGTCGCCATTATTGGTATAACA
ACTTTTGTGAGGACATAGCG

Downstream 100 bases:

>100_bases
TCGCGGCAATGGGGATAATAAAAAGGACAGCCAGCGCTGTCCTTTTTTACTGTCGGGGCGTTACCGATGATTAATCCGCG
CGGCCCATATAGCGGCACTC

Product: mannonate dehydratase

Products: NA

Alternate protein names: D-mannonate hydrolase [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIANGQVWPVDEIKARQALLAAKGLTWSVVESIPVHEDIKTHSGQYAT
WIANYQQSIRNLAACGIDTVCYNFMPILDWTRTDLEYELPDGSRALRFDQIAFAAFELHILKRPGAEADYSEEEQRQAEV
YLKAMSEADIDKLTRNIIAGLPGAEEGYTLDQFRARLAEYDHIDKAQLRENMAYFLRAIVPVCEEVGIRLAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSINNGFTMCTGSYGVRADNDLVKMVETFGDRIHFTHLRSTCREANPKTFHEAAHLSGD
VNMVAVVDAILREEQRRKQAGDLRPIPFRPDHGHQMLDDLRKKTNPGYSAIGRLKGMAEVRGVELALKMTKYPELL

Sequences:

>Translated_396_residues
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIANGQVWPVDEIKARQALLAAKGLTWSVVESIPVHEDIKTHSGQYAT
WIANYQQSIRNLAACGIDTVCYNFMPILDWTRTDLEYELPDGSRALRFDQIAFAAFELHILKRPGAEADYSEEEQRQAEV
YLKAMSEADIDKLTRNIIAGLPGAEEGYTLDQFRARLAEYDHIDKAQLRENMAYFLRAIVPVCEEVGIRLAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSINNGFTMCTGSYGVRADNDLVKMVETFGDRIHFTHLRSTCREANPKTFHEAAHLSGD
VNMVAVVDAILREEQRRKQAGDLRPIPFRPDHGHQMLDDLRKKTNPGYSAIGRLKGMAEVRGVELALKMTKYPELL
>Mature_396_residues
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIANGQVWPVDEIKARQALLAAKGLTWSVVESIPVHEDIKTHSGQYAT
WIANYQQSIRNLAACGIDTVCYNFMPILDWTRTDLEYELPDGSRALRFDQIAFAAFELHILKRPGAEADYSEEEQRQAEV
YLKAMSEADIDKLTRNIIAGLPGAEEGYTLDQFRARLAEYDHIDKAQLRENMAYFLRAIVPVCEEVGIRLAVHPDDPPRP
ILGLPRIVSTIEDMQWLKETVDSINNGFTMCTGSYGVRADNDLVKMVETFGDRIHFTHLRSTCREANPKTFHEAAHLSGD
VNMVAVVDAILREEQRRKQAGDLRPIPFRPDHGHQMLDDLRKKTNPGYSAIGRLKGMAEVRGVELALKMTKYPELL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1312

COG function: function code G; D-mannonate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannonate dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1790778, Length=388, Percent_Identity=76.8041237113402, Blast_Score=634, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004628
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03786 UxuA [H]

EC number: =4.2.1.8 [H]

Molecular weight: Translated: 44736; Mature: 44736

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIANGQVWPVDEIKARQALLAAKGLTWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
VVESIPVHEDIKTHSGQYATWIANYQQSIRNLAACGIDTVCYNFMPILDWTRTDLEYELP
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DGSRALRFDQIAFAAFELHILKRPGAEADYSEEEQRQAEVYLKAMSEADIDKLTRNIIAG
CCCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPGAEEGYTLDQFRARLAEYDHIDKAQLRENMAYFLRAIVPVCEEVGIRLAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
ILGLPRIVSTIEDMQWLKETVDSINNGFTMCTGSYGVRADNDLVKMVETFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEHHHHH
STCREANPKTFHEAAHLSGDVNMVAVVDAILREEQRRKQAGDLRPIPFRPDHGHQMLDDL
HHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RKKTNPGYSAIGRLKGMAEVRGVELALKMTKYPELL
HHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCC
>Mature Secondary Structure
MEQTWRWYGPNDPVSLDDVRQAGATGVVTALHHIANGQVWPVDEIKARQALLAAKGLTWS
CCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
VVESIPVHEDIKTHSGQYATWIANYQQSIRNLAACGIDTVCYNFMPILDWTRTDLEYELP
HHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
DGSRALRFDQIAFAAFELHILKRPGAEADYSEEEQRQAEVYLKAMSEADIDKLTRNIIAG
CCCCCHHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LPGAEEGYTLDQFRARLAEYDHIDKAQLRENMAYFLRAIVPVCEEVGIRLAVHPDDPPRP
CCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
ILGLPRIVSTIEDMQWLKETVDSINNGFTMCTGSYGVRADNDLVKMVETFGDRIHFTHLR
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEHHHHH
STCREANPKTFHEAAHLSGDVNMVAVVDAILREEQRRKQAGDLRPIPFRPDHGHQMLDDL
HHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
RKKTNPGYSAIGRLKGMAEVRGVELALKMTKYPELL
HHHCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA