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The map label for this gene is mglC [H]

Identifier: 238895712

GI number: 238895712

Start: 3640328

End: 3641338

Strand: Reverse

Name: mglC [H]

Synonym: KP1_3813

Alternate gene names: 238895712

Gene position: 3641338-3640328 (Counterclockwise)

Preceding gene: 238895713

Following gene: 238895707

Centisome position: 69.38

GC content: 55.29

Gene sequence:

>1011_bases
ATGAGTGCGTTAAATAAAAAGAGTTTTCTCACTTACCTGAAAGAGGGTGGGATATATGTTGTCCTTCTGGTCCTGCTGGC
CATTATTATTTTCCAGGATCCGACATTTTTAAGTCTGCTCAACCTGAGTAATATTCTGACCCAGTCCTCGGTGCGTATTA
TTATTGCCCTCGGCGTGGCCGGACTTATCGTCACGCAGGGGACCGACCTCTCCGCCGGCCGTCAGGTGGGTCTGGCGGCG
GTGATTGCCGCCACCATGCTGCAGGCGGTGGATAATGCCAATAAGGTATTCCCGGATATGGCGACCATGCCGATCCCGCT
GGTGATCCTGCTGGTGTGCGCCATCGGGGCGGTCATCGGCCTGATTAACGGGATCGTCATTGCCTACCTGAACGTGACGC
CGTTTATTACCACTCTCGGCACCATGATTATCGTCTACGGCATTAACTCGCTGTACTACGACTTCGTGGGCGCGTCGCCG
ATCTCCGGCTTCGACAGCCACTTCTCCCATTTCGCGCAGGGGTTTGTGGCGCTGGGCTCCTTCCGCCTGTCCTACATTAC
CTTCTACGCGCTGATTGCCGTCTTCTTTGTCTGGATCCTGTGGAACAAGACGCGCTTTGGCAAAAACATTTTCGCTATCG
GCGGTAACCCGGAAGCGGCGAAGGTCTCCGGGGTTAACGTAGCGTTAAACCTGCTGATGATCTATGCCCTCTCCGGCGTG
TTCTACGCCTTCGGCGGCCTGCTGGAAGCCGGACGTATCGGTTCGGCGACCAATAACCTCGGCTTTATGTATGAACTGGA
CGCCATCGCCGCCTGTGTGGTGGGCGGCGTATCGTTCAGCGGCGGGGTAGGGACGGTGTTTGGCGTGGTGACCGGGGTGA
TTATCTTCACCGTCATCAACTACGGCCTGACCTATATCGGCGTCAACCCTTACTGGCAGTACATTATTAAGGGGGCGATT
ATTATCTTCGCCGTGGCGCTGGACTCCCTGAAATACGCCCGTAAGAAATAA

Upstream 100 bases:

>100_bases
GAGCAACGGCCTGGTCGCGGGCATTGTTGAGACTAAAACCACCACGCAAAACGAAATACTGCGTCTTGCGTCATTGCACC
TTTAAGATCAGGGGCTTCAC

Downstream 100 bases:

>100_bases
GATTGAACGCATCAAAAACCCGCGCCTGGCGCGGGTTTTTTTATATCTGAAACGAATGCGTTGATGGAGGCTACTTTTCT
TTCTGCAGCTCCAGCAGCTG

Product: beta-methylgalactoside transporter inner membrane component

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VIAATMLQAVDNANKVFPDMATMPIPLVILLVCAIGAVIGLINGIVIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSHFSHFAQGFVALGSFRLSYITFYALIAVFFVWILWNKTRFGKNIFAIGGNPEAAKVSGVNVALNLLMIYALSGV
FYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVFGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK

Sequences:

>Translated_336_residues
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VIAATMLQAVDNANKVFPDMATMPIPLVILLVCAIGAVIGLINGIVIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSHFSHFAQGFVALGSFRLSYITFYALIAVFFVWILWNKTRFGKNIFAIGGNPEAAKVSGVNVALNLLMIYALSGV
FYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVFGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK
>Mature_335_residues
SALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAV
IAATMLQAVDNANKVFPDMATMPIPLVILLVCAIGAVIGLINGIVIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPI
SGFDSHFSHFAQGFVALGSFRLSYITFYALIAVFFVWILWNKTRFGKNIFAIGGNPEAAKVSGVNVALNLLMIYALSGVF
YAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVFGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAII
IFAVALDSLKYARKK

Specific function: Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4211

COG function: function code G; ABC-type glucose/galactose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788471, Length=336, Percent_Identity=95.2380952380952, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1790191, Length=323, Percent_Identity=33.4365325077399, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789992, Length=376, Percent_Identity=31.1170212765957, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790524, Length=333, Percent_Identity=33.9339339339339, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788896, Length=332, Percent_Identity=32.2289156626506, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI145693152, Length=214, Percent_Identity=36.4485981308411, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787794, Length=304, Percent_Identity=32.2368421052632, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI87082395, Length=303, Percent_Identity=32.3432343234323, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1787793, Length=307, Percent_Identity=27.3615635179153, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI145693214, Length=269, Percent_Identity=32.7137546468402, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 35769; Mature: 35638

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVA
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEHHH
GLIVTQGTDLSAGRQVGLAAVIAATMLQAVDNANKVFPDMATMPIPLVILLVCAIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCHHCCHHHHHHHHHHHHHHHHH
LINGIVIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSHFSHFAQGFVALGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FRLSYITFYALIAVFFVWILWNKTRFGKNIFAIGGNPEAAKVSGVNVALNLLMIYALSGV
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECHHHHHHHHHHHHHHHHH
FYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVFGVVTGVIIFTVIN
HHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSNILTQSSVRIIIALGVA
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEEEEHHH
GLIVTQGTDLSAGRQVGLAAVIAATMLQAVDNANKVFPDMATMPIPLVILLVCAIGAVIG
HHEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCHHCCHHHHHHHHHHHHHHHHH
LINGIVIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASPISGFDSHFSHFAQGFVALGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FRLSYITFYALIAVFFVWILWNKTRFGKNIFAIGGNPEAAKVSGVNVALNLLMIYALSGV
HHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEECCCCCCCEECHHHHHHHHHHHHHHHHH
FYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVFGVVTGVIIFTVIN
HHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
YGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYARKK
CCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1719366; 9278503 [H]