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The map label for this gene is yehW [H]

Identifier: 238895690

GI number: 238895690

Start: 3616459

End: 3617196

Strand: Reverse

Name: yehW [H]

Synonym: KP1_3790

Alternate gene names: 238895690

Gene position: 3617196-3616459 (Counterclockwise)

Preceding gene: 238895691

Following gene: 238895689

Centisome position: 68.92

GC content: 67.21

Gene sequence:

>738_bases
ATGAAGGCGCTTCGTGAGCCGCTGTGGTGGCTTATCGCGCTGTTTATCGGCCTGCTGGCAGGGCTGCCCTACAGCGCGCC
GCTGTTCAGTCGGCTGTTCCCGGAGCTGCCGCGGCCGGTCTACCAGCAGGAGAGCTTCTGGGCGCTCACTCTCGATCACG
GCTGGCTGGTGGTGGCGTCCAGCCTCGCGGCAACGGCAATCGGGCTGGGGGCTGGGGTGGCGGTCACCCGGCCCGCCGGC
GGCGCGTTTCGTCCGCTGGTGGAGACCATCGCCGCTATCGGGCAGACCTTTCCGCCGGTGGCGGTGCTGGCGATGGCGGT
GCCGGTGCTGGGCTTTGGCTGGCTGCCGGCGCTGATAGCCCTCGCGCTGTATGGCATACTGCCGGTGCTGCAGGGGACGC
TGGCCGGGCTGGGTTCGATACCGCCGGGGGTGTCAGGTGTGGCTGAAGGGATGGGAATGACCGGCTGGCAGCGTCTGTAT
AAGGTGGAGCTACCGCTGGCGGCCCCGGTGATCCTGGCGGGGATCCGCACCTCGGTCATCGTCAATATTGGTACCGCGAC
CATTGCCTCGACGGTGGGGGCCAGTACGCTCGGGACGCCGATCATCATCGGCCTGAGCGGCTTTAATACCGCCTATATTG
TTCAGGGGGCGCTGCTGGTGGCCCTGGCGGCGATTATCGTCGACCGCGCGTTTGAGCGTCTGACCCGCTGGATCAGCCGA
CACCGCCACGCACAATAA

Upstream 100 bases:

>100_bases
TTTGTCGCCCGGCGCTGCGAGACGCTGCCGGTGGTCGATGCCGAAGGCAGGCCCTGCGGTACGCTGCATTTTGCCGATCT
GCTGCGTCAGGAGATGAGCC

Downstream 100 bases:

>100_bases
AGGAATAGCCGGCCAGCATTACGCCGCTGATCCCGCCGATGGCCATAAGTAAGAAGAGGGTGACGACCGCGATTTTCGCT
GGCTTCATAATAGGCTCCTG

Product: putative ABC-type proline/glycine betaine transport system inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MKALREPLWWLIALFIGLLAGLPYSAPLFSRLFPELPRPVYQQESFWALTLDHGWLVVASSLAATAIGLGAGVAVTRPAG
GAFRPLVETIAAIGQTFPPVAVLAMAVPVLGFGWLPALIALALYGILPVLQGTLAGLGSIPPGVSGVAEGMGMTGWQRLY
KVELPLAAPVILAGIRTSVIVNIGTATIASTVGASTLGTPIIIGLSGFNTAYIVQGALLVALAAIIVDRAFERLTRWISR
HRHAQ

Sequences:

>Translated_245_residues
MKALREPLWWLIALFIGLLAGLPYSAPLFSRLFPELPRPVYQQESFWALTLDHGWLVVASSLAATAIGLGAGVAVTRPAG
GAFRPLVETIAAIGQTFPPVAVLAMAVPVLGFGWLPALIALALYGILPVLQGTLAGLGSIPPGVSGVAEGMGMTGWQRLY
KVELPLAAPVILAGIRTSVIVNIGTATIASTVGASTLGTPIIIGLSGFNTAYIVQGALLVALAAIIVDRAFERLTRWISR
HRHAQ
>Mature_245_residues
MKALREPLWWLIALFIGLLAGLPYSAPLFSRLFPELPRPVYQQESFWALTLDHGWLVVASSLAATAIGLGAGVAVTRPAG
GAFRPLVETIAAIGQTFPPVAVLAMAVPVLGFGWLPALIALALYGILPVLQGTLAGLGSIPPGVSGVAEGMGMTGWQRLY
KVELPLAAPVILAGIRTSVIVNIGTATIASTVGASTLGTPIIIGLSGFNTAYIVQGALLVALAAIIVDRAFERLTRWISR
HRHAQ

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=241, Percent_Identity=75.9336099585062, Blast_Score=346, Evalue=9e-97,
Organism=Escherichia coli, GI1788451, Length=254, Percent_Identity=31.8897637795276, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789033, Length=178, Percent_Identity=28.0898876404494, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25616; Mature: 25616

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALREPLWWLIALFIGLLAGLPYSAPLFSRLFPELPRPVYQQESFWALTLDHGWLVVAS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHCCCCEEEEEECCCHHHHHH
SLAATAIGLGAGVAVTRPAGGAFRPLVETIAAIGQTFPPVAVLAMAVPVLGFGWLPALIA
HHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LALYGILPVLQGTLAGLGSIPPGVSGVAEGMGMTGWQRLYKVELPLAAPVILAGIRTSVI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHE
VNIGTATIASTVGASTLGTPIIIGLSGFNTAYIVQGALLVALAAIIVDRAFERLTRWISR
EECCHHHHHHHHCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRHAQ
HCCCC
>Mature Secondary Structure
MKALREPLWWLIALFIGLLAGLPYSAPLFSRLFPELPRPVYQQESFWALTLDHGWLVVAS
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHCCCCEEEEEECCCHHHHHH
SLAATAIGLGAGVAVTRPAGGAFRPLVETIAAIGQTFPPVAVLAMAVPVLGFGWLPALIA
HHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LALYGILPVLQGTLAGLGSIPPGVSGVAEGMGMTGWQRLYKVELPLAAPVILAGIRTSVI
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHE
VNIGTATIASTVGASTLGTPIIIGLSGFNTAYIVQGALLVALAAIIVDRAFERLTRWISR
EECCHHHHHHHHCHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HRHAQ
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]