Click here to switch to the map view.

The map label for this gene is iroN [H]

Identifier: 238895531

GI number: 238895531

Start: 3433588

End: 3435762

Strand: Reverse

Name: iroN [H]

Synonym: KP1_3609

Alternate gene names: 238895531

Gene position: 3435762-3433588 (Counterclockwise)

Preceding gene: 238895535

Following gene: 238895527

Centisome position: 65.46

GC content: 51.91

Gene sequence:

>2175_bases
ATGAGAATTAACAAGATCCTCTGTCCGCTAACTGCGCTCCTAGTAGGGTTGAATAGTCAAGTATCAGTAGCCAAATCCTC
CGACGATAACGACGAGACCTTGGTCGTGGAAGCCACCGCTGAGCAGCTACTAAAACAGCAGCCGGGCGTGTCGATTATTA
CCAGCGAAGATATTATAAAGAACCCTCCGGTCAACGACCTCTCCGATATTATTCGCAAAATGCCTGGTGTCAATCTGACC
GGCAATAGCGCCTCGGGGACACGCGGTAATAACCGCCAGATCGACATGCGCGGTATGGGGCCGGAAAACACATTAATTTT
AATTGATGGTGTACCGGTGACGTCGCGCAACTCCGTGCGTTATAGCTGGCGCGGGGAGCGTGATACCCGCGGCGACACCA
ACTGGGTGCCACCAGAACAGGTTGAGCGTATCGAAGTGATCCGCGGCCCTGCGGCGGCGCGCTACGGTTCGGGCGCCGCG
GGCGGGGTGGTAAACATCATTACCAAACGCCCCTCCAACGACTGGCACGGTTCGCTGTCGCTATACACCAACCAGCCAGA
AAGCAGCGATGAAGGCGCTACGCGTCGCGCCAACTTCAGCCTTAGTGGGCCGCTGGCTGGCGATGCGCTGACCATGCGCC
TCTACGGTAACCTGAATAAAACCGATGCCGACAGCTGGGATATTAACTCCTCGGCCGGAACGAAAAACGCGGCCGGGCAT
GAAGGGGTGCGCAACAAAGATATTAACGGCGTTGTTTCGTGGAAATTAAATCCGCAGCAAATTCTTGATTTCGAAGCCGG
ATATAGTCGTCAGGGGAATATTTATGCGGGCGATACGCAAAACAGTTCTTCTAGTGCCGTAACTGAAAGCTTGGCGAAAT
CCGGCGAAGAGACGAACCGCCTGTACCGGCAGAATTATGGCATTACGCATAATGGCATCTGGGACTGGGGACAAAGCCGT
TTTGGTGTCTATTACGAGAAAACCAATAACACCCGCATGAATGAAGGATTATCCGGCGGCGGTGAAGGGCGTATTTTGGC
GGATGAAAAGTTCACAACCAATCGCCTGAGCACCTTGCGAACCAGCGGCGAGCTTAATATTCCGCTGAATACGCTGGTCG
ATCAAACGCTGACCGTGGGGGCGGAGTGGAGCCGCGATGAACTCGACGATCCTTCCTCTACCAGCCTGACGGTGGATGAC
AGTGATATCGGCGGCATTTCTGGCTCGGCTGCGGATCGCAGCAGTAAAAACCATTCCCAAATCAGTGCGCTGTATATTGA
AGATAATATTGAGCAGGTTCCCGGCACGAATATAATTCCCGGCTTGCGCTTTGATTATCTCAACGAGTCCGGCGGTAACT
TCAGCCCCAGCCTTAACCTCTCGCAGGAATTGGGCGATTACTTCAAAGTCAAAGCGGGGATTGCCCGAACCTTCAAAGCA
CCAAACTTGTATCAATCCAGCGAAGGTTATCTGCTCTACTCGAAAGGCAACGGTTGTCCAAAAGATATTACATCGGGTGG
TTGCTACCTGATCGGTAATAAAAATCTCGATCCGGAAATCAGTATCAATAAAGAAATTGGGCTGGAGTTCGCCTGGGAAG
ATTACCACGCCAGCGTGACCTACTTCCGCAATGACTACCAGAATAAGATCTTGGCCGGGGATAATGTTATCGGGCAAACC
GCTTCAGGCACATATATCCTCCAGTGGCAGAATGGAGGAAAAGCGCTGGTGGACGGTATCGAAGCCAGCATGGCGTTCCC
GCTGGTGAAAGATCGTCTGAACTGGAATACCAATGCCACCTGGATGATCACCTCGGAGCAAAAAGACACAGGTAACCCGC
TGTCGGTCATCCCGAAATATACCATTAATAACTCGCTTGACTGGACCATCACCCAAGCGTTTTCCGCCAGCGTCAACTGG
ACGTTATACGGCAGACAAAAACCGCGTACCCATGCGGAAACTCGGAGTGAAGATACTGGCGGCCTGTCAGGTAAAGAGCT
GGGAGCTTATTCGCTGGTGGGGACGAACTTCAATTACGATATTAATAAAAATCTTCGTCTTAACGTCGGTGTTAGCAATA
TCTTCGATAAACAGATTTACCGATCTTCCGAAGGGGCGAATACTTATAACGAGCCTGGCCGGGCTTATTATGCCGGTGTC
ACCGCATCATTCTGA

Upstream 100 bases:

>100_bases
ATTCTTATAATAAAACAATAATGACAGTAAAAAATATCTGGCAAGGATGTGAGCTTAACGATCAACCACTTTTAAGTTAG
GCATTCATTAGGGAATGGGT

Downstream 100 bases:

>100_bases
TCGTAGTGTTACAGGTGTACTGCCTGCGTAAAGGCGGGCAGTGTTTAGCGGCTTATCATCAACGTAAAGTGTTAATTCCT
GTTCCCGTCATGATGCTCCC

Product: outer membrane receptor FepA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MRINKILCPLTALLVGLNSQVSVAKSSDDNDETLVVEATAEQLLKQQPGVSIITSEDIIKNPPVNDLSDIIRKMPGVNLT
GNSASGTRGNNRQIDMRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAA
GGVVNIITKRPSNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGDALTMRLYGNLNKTDADSWDINSSAGTKNAAGH
EGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGEETNRLYRQNYGITHNGIWDWGQSR
FGVYYEKTNNTRMNEGLSGGGEGRILADEKFTTNRLSTLRTSGELNIPLNTLVDQTLTVGAEWSRDELDDPSSTSLTVDD
SDIGGISGSAADRSSKNHSQISALYIEDNIEQVPGTNIIPGLRFDYLNESGGNFSPSLNLSQELGDYFKVKAGIARTFKA
PNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKNLDPEISINKEIGLEFAWEDYHASVTYFRNDYQNKILAGDNVIGQT
ASGTYILQWQNGGKALVDGIEASMAFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLDWTITQAFSASVNW
TLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNIFDKQIYRSSEGANTYNEPGRAYYAGV
TASF

Sequences:

>Translated_724_residues
MRINKILCPLTALLVGLNSQVSVAKSSDDNDETLVVEATAEQLLKQQPGVSIITSEDIIKNPPVNDLSDIIRKMPGVNLT
GNSASGTRGNNRQIDMRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAA
GGVVNIITKRPSNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGDALTMRLYGNLNKTDADSWDINSSAGTKNAAGH
EGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGEETNRLYRQNYGITHNGIWDWGQSR
FGVYYEKTNNTRMNEGLSGGGEGRILADEKFTTNRLSTLRTSGELNIPLNTLVDQTLTVGAEWSRDELDDPSSTSLTVDD
SDIGGISGSAADRSSKNHSQISALYIEDNIEQVPGTNIIPGLRFDYLNESGGNFSPSLNLSQELGDYFKVKAGIARTFKA
PNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKNLDPEISINKEIGLEFAWEDYHASVTYFRNDYQNKILAGDNVIGQT
ASGTYILQWQNGGKALVDGIEASMAFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLDWTITQAFSASVNW
TLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNIFDKQIYRSSEGANTYNEPGRAYYAGV
TASF
>Mature_724_residues
MRINKILCPLTALLVGLNSQVSVAKSSDDNDETLVVEATAEQLLKQQPGVSIITSEDIIKNPPVNDLSDIIRKMPGVNLT
GNSASGTRGNNRQIDMRGMGPENTLILIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAA
GGVVNIITKRPSNDWHGSLSLYTNQPESSDEGATRRANFSLSGPLAGDALTMRLYGNLNKTDADSWDINSSAGTKNAAGH
EGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGEETNRLYRQNYGITHNGIWDWGQSR
FGVYYEKTNNTRMNEGLSGGGEGRILADEKFTTNRLSTLRTSGELNIPLNTLVDQTLTVGAEWSRDELDDPSSTSLTVDD
SDIGGISGSAADRSSKNHSQISALYIEDNIEQVPGTNIIPGLRFDYLNESGGNFSPSLNLSQELGDYFKVKAGIARTFKA
PNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKNLDPEISINKEIGLEFAWEDYHASVTYFRNDYQNKILAGDNVIGQT
ASGTYILQWQNGGKALVDGIEASMAFPLVKDRLNWNTNATWMITSEQKDTGNPLSVIPKYTINNSLDWTITQAFSASVNW
TLYGRQKPRTHAETRSEDTGGLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNIFDKQIYRSSEGANTYNEPGRAYYAGV
TASF

Specific function: Specific receptor for the siderophore ferric enterobactin [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=756, Percent_Identity=52.3809523809524, Blast_Score=713, Evalue=0.0,
Organism=Escherichia coli, GI1788478, Length=726, Percent_Identity=33.1955922865014, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1790405, Length=725, Percent_Identity=23.448275862069, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1787024, Length=184, Percent_Identity=29.8913043478261, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79020; Mature: 79020

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00449 ATPASE_A ; PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINKILCPLTALLVGLNSQVSVAKSSDDNDETLVVEATAEQLLKQQPGVSIITSEDIIK
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHCCCCEEEECCHHHC
NPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDMRGMGPENTLILIDGVPVTSRNSVR
CCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCEE
YSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPSNDWHGSLS
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCCCEEEE
LYTNQPESSDEGATRRANFSLSGPLAGDALTMRLYGNLNKTDADSWDINSSAGTKNAAGH
EEECCCCCCCCCCCEEECEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
EGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGEETNR
CCCCCCCCCEEEEEEECHHHHEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHCCHHHHH
LYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILADEKFTTNRLSTLR
HHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHC
TSGELNIPLNTLVDQTLTVGAEWSRDELDDPSSTSLTVDDSDIGGISGSAADRSSKNHSQ
CCCCCCCCHHHHHCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCE
ISALYIEDNIEQVPGTNIIPGLRFDYLNESGGNFSPSLNLSQELGDYFKVKAGIARTFKA
EEEEEEECCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHEEEHHHHHHHCCC
PNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKNLDPEISINKEIGLEFAWEDYHASVT
CCCEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCEEEECCCCCEEE
YFRNDYQNKILAGDNVIGQTASGTYILQWQNGGKALVDGIEASMAFPLVKDRLNWNTNAT
EEECCCCCCEEECCCEECCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHCCCCCCEE
WMITSEQKDTGNPLSVIPKYTINNSLDWTITQAFSASVNWTLYGRQKPRTHAETRSEDTG
EEEECCCCCCCCCEEEEEEEEECCCCCEEEEEEECCEEEEEEEECCCCCCHHHCCCCCCC
GLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNIFDKQIYRSSEGANTYNEPGRAYYAGV
CCCCCCCCEEEEEECCCCEECCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
TASF
EECC
>Mature Secondary Structure
MRINKILCPLTALLVGLNSQVSVAKSSDDNDETLVVEATAEQLLKQQPGVSIITSEDIIK
CCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHCCCCEEEECCHHHC
NPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDMRGMGPENTLILIDGVPVTSRNSVR
CCCCHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCEE
YSWRGERDTRGDTNWVPPEQVERIEVIRGPAAARYGSGAAGGVVNIITKRPSNDWHGSLS
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCCCEEEE
LYTNQPESSDEGATRRANFSLSGPLAGDALTMRLYGNLNKTDADSWDINSSAGTKNAAGH
EEECCCCCCCCCCCEEECEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
EGVRNKDINGVVSWKLNPQQILDFEAGYSRQGNIYAGDTQNSSSSAVTESLAKSGEETNR
CCCCCCCCCEEEEEEECHHHHEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHCCHHHHH
LYRQNYGITHNGIWDWGQSRFGVYYEKTNNTRMNEGLSGGGEGRILADEKFTTNRLSTLR
HHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHC
TSGELNIPLNTLVDQTLTVGAEWSRDELDDPSSTSLTVDDSDIGGISGSAADRSSKNHSQ
CCCCCCCCHHHHHCCCEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCE
ISALYIEDNIEQVPGTNIIPGLRFDYLNESGGNFSPSLNLSQELGDYFKVKAGIARTFKA
EEEEEEECCHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHEEEHHHHHHHCCC
PNLYQSSEGYLLYSKGNGCPKDITSGGCYLIGNKNLDPEISINKEIGLEFAWEDYHASVT
CCCEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCEEEECCCCCEEE
YFRNDYQNKILAGDNVIGQTASGTYILQWQNGGKALVDGIEASMAFPLVKDRLNWNTNAT
EEECCCCCCEEECCCEECCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHCCCCCCEE
WMITSEQKDTGNPLSVIPKYTINNSLDWTITQAFSASVNWTLYGRQKPRTHAETRSEDTG
EEEECCCCCCCCCEEEEEEEEECCCCCEEEEEEECCEEEEEEEECCCCCCHHHCCCCCCC
GLSGKELGAYSLVGTNFNYDINKNLRLNVGVSNIFDKQIYRSSEGANTYNEPGRAYYAGV
CCCCCCCCEEEEEECCCCEECCCCEEEEECHHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
TASF
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419284; 10984043 [H]