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The map label for this gene is uvrC [H]

Identifier: 238895471

GI number: 238895471

Start: 3357498

End: 3359330

Strand: Reverse

Name: uvrC [H]

Synonym: KP1_3541

Alternate gene names: 238895471

Gene position: 3359330-3357498 (Counterclockwise)

Preceding gene: 238895472

Following gene: 238895470

Centisome position: 64.01

GC content: 57.61

Gene sequence:

>1833_bases
GTGAGTGATGTTTTTGACGCAAAAGCTTTCCTGAAAACGGTGACCAGCCAGCCCGGTGTGTATCGGATGTATGATGCTGG
CGGAACCGTCATCTATGTTGGCAAAGCCAAAGATCTGAAAAAGCGGCTCAGTAGCTACTTCCGCAGCAACCTTGCGTCGC
GTAAAACGGAAGCGCTGGTAGCGCTGATCGCGCAAATCGACGTGACCGTCACCCACACCGAGACGGAAGCGCTGCTGCTT
GAGCACAACTATATTAAGCTGTACCAGCCACGTTACAACGTGCTGTTACGCGACGATAAATCGTATCCTTTTATTTTTCT
CAGCGGCGATACTCATCCGCGTCTGGCGATGCATCGCGGCGCCAAACATGCGAAGGGCGAGTATTTTGGTCCTTTTCCCA
ACGGCTATGCCGTGCGCGAGACCCTGGCGCTGCTGCAGAAAATCTTTCCCATCCGTCAGTGTGAAAACAGCGTCTACCGC
AATCGCTCCCGCCCCTGTCTGCAGTATCAGATTGGTCGCTGCCTGGGGCCGTGCGTGGCCGGGCTGGTCAGCGAAGAAGA
GTATGCTCAGCAGGTAGAGTATGTGCGGCTGTTTCTCGCCGGCAAGGATGACCAGGTGCTGACCCAGCTCATCGCGCGGA
TGGAGAAGGCGAGCCAGAACCTGGAGTTCGAAGAGGCCGCGCGCATCCGCGACCAGATTCAGGCCGTCCGCCGCGTGACG
GAGAAACAGTTTGTCTCCAACACCGGTGACGACCTCGACGTGATCGGCGTCGCCTTCGATGCCGGCATGGCCTGCGTGCA
TGTGCTGTTTATCCGTCAGGGCAAAGTGCTGGGCAGCCGAAGCTACTTCCCGAAAGTGCCGGGCGGCACCGAGCTGGGAG
AGGTCGTGGAGACCTTTGTCGGCCAGTTCTACCTGCAGGGCAGCCAAATGCGCACGCTGCCGGGGGAGATTTTGCTCGAC
TTTAACCTTGGGGATAAGACGCTGCTGGCCGACTCGCTGTCGGAGCTGGCGGGTCGTCGAATCAATGTGCAGACTAAGCC
GCGCGGCGACAGAGCGCGTTATCTTAAGCTGGCGCGGACCAACGCCGCGACAGCGTTAACGACCAAATTGTCTCAGCAAT
CGACCATTCATCAGCGTTTGCAGGCGCTGGCCAGCGTACTGGAGCTGCCGGCCGTCAAGCGAATGGAGTGTTTTGACATC
AGCCACACCATGGGCGAACAGACCGTAGCATCCTGTGTGGTGTTTGACAGCAATGGCCCACTGCGCGCGGAGTATCGGCG
CTACAACATCACCGGCATTACCCCTGGCGATGACTATGCGGCGATGAATCAGGTCCTGCGCCGTCGCTATGGTAAAGCGA
TTGATGACAACAAGATCCCGGATGTGATCCTGATAGACGGCGGCAAGGGACAGCTGGCCCAGGCGAAAGCCGTGTTTGCT
GAACTGGACGTCCCCTGGGATAAACATCATCCGCTGCTGCTGGGCGTGGCGAAAGGTAGCGATCGAAAAGCGGGTCTGGA
AACGTTATTCTTTGAGCCGGAAGGGGAAGGGTTTAGCCTGCCGCCGGATTCGCCGGCCCTGCATGTGATCCAGCATATTC
GCGATGAATCGCACGATCATGCGATCTCCGGGCATCGCAAAAAACGGGCGAAAGTGAAGAGCACCAGCTCGCTTGAGACT
ATCGAGGGGGTGGGGCCGAAGCGTCGTCAGATGCTGCTGAAGTATATGGGTGGGCTGCAGGGGCTACAGCAGGCCAGCGT
CGAAGAAATTGCTAAAGTACCGGGCATCTCTCACGCTCTGGCAGAAAAGATCTTCTACTCGTTGAAACATTAG

Upstream 100 bases:

>100_bases
GCTATCGGATGTTCAGTAAATTAAACATTCATGGCGATGTCGAGCTGACCCACCTGGCAATTCGCCATGGCCTGTGTAAT
GCGGAGTCGTTAGCAAGCCA

Downstream 100 bases:

>100_bases
GGGCTCTGTAGCAACATAGGGCTAATTTTTACTTACAACAGATAGTTACCCGTCACTATGCAATTTAATATCCCTACGTT
GCTTACTCTGTTTCGCGTCA

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSDVFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVALIAQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLAGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLD
FNLGDKTLLADSLSELAGRRINVQTKPRGDRARYLKLARTNAATALTTKLSQQSTIHQRLQALASVLELPAVKRMECFDI
SHTMGEQTVASCVVFDSNGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDNKIPDVILIDGGKGQLAQAKAVFA
ELDVPWDKHHPLLLGVAKGSDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAISGHRKKRAKVKSTSSLET
IEGVGPKRRQMLLKYMGGLQGLQQASVEEIAKVPGISHALAEKIFYSLKH

Sequences:

>Translated_610_residues
MSDVFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVALIAQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLAGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLD
FNLGDKTLLADSLSELAGRRINVQTKPRGDRARYLKLARTNAATALTTKLSQQSTIHQRLQALASVLELPAVKRMECFDI
SHTMGEQTVASCVVFDSNGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDNKIPDVILIDGGKGQLAQAKAVFA
ELDVPWDKHHPLLLGVAKGSDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAISGHRKKRAKVKSTSSLET
IEGVGPKRRQMLLKYMGGLQGLQQASVEEIAKVPGISHALAEKIFYSLKH
>Mature_609_residues
SDVFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVALIAQIDVTVTHTETEALLLE
HNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRN
RSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLAGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVTE
KQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDF
NLGDKTLLADSLSELAGRRINVQTKPRGDRARYLKLARTNAATALTTKLSQQSTIHQRLQALASVLELPAVKRMECFDIS
HTMGEQTVASCVVFDSNGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDNKIPDVILIDGGKGQLAQAKAVFAE
LDVPWDKHHPLLLGVAKGSDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAISGHRKKRAKVKSTSSLETI
EGVGPKRRQMLLKYMGGLQGLQQASVEEIAKVPGISHALAEKIFYSLKH

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=95.4098360655738, Blast_Score=1207, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF00633 HHH; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68029; Mature: 67898

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALV
CCCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ALIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRG
HHHHHHCEEEEECCCEEEEEECCEEEEECCCCCEEEECCCCCCEEEECCCCCCHHHHHCC
AKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GLVSEEEYAQQVEYVRLFLAGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVT
HHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFV
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHH
GQFYLQGSQMRTLPGEILLDFNLGDKTLLADSLSELAGRRINVQTKPRGDRARYLKLART
HHHHCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHC
NAATALTTKLSQQSTIHQRLQALASVLELPAVKRMECFDISHTMGEQTVASCVVFDSNGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHEEEEEECCCCC
LRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDNKIPDVILIDGGKGQLAQAKAVFA
CEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
ELDVPWDKHHPLLLGVAKGSDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDH
HCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCC
AISGHRKKRAKVKSTSSLETIEGVGPKRRQMLLKYMGGLQGLQQASVEEIAKVPGISHAL
HHCCCHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AEKIFYSLKH
HHHHHHHHCC
>Mature Secondary Structure 
SDVFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALV
CCHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
ALIAQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRG
HHHHHHCEEEEECCCEEEEEECCEEEEECCCCCEEEECCCCCCEEEECCCCCCHHHHHCC
AKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
GLVSEEEYAQQVEYVRLFLAGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVT
HHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFV
HHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHH
GQFYLQGSQMRTLPGEILLDFNLGDKTLLADSLSELAGRRINVQTKPRGDRARYLKLART
HHHHCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHC
NAATALTTKLSQQSTIHQRLQALASVLELPAVKRMECFDISHTMGEQTVASCVVFDSNGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHEEEEEECCCCC
LRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDNKIPDVILIDGGKGQLAQAKAVFA
CEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
ELDVPWDKHHPLLLGVAKGSDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDH
HCCCCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCC
AISGHRKKRAKVKSTSSLETIEGVGPKRRQMLLKYMGGLQGLQQASVEEIAKVPGISHAL
HHCCCHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AEKIFYSLKH
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA