Click here to switch to the map view.

The map label for this gene is otsB [H]

Identifier: 238895455

GI number: 238895455

Start: 3341709

End: 3342497

Strand: Reverse

Name: otsB [H]

Synonym: KP1_3524

Alternate gene names: 238895455

Gene position: 3342497-3341709 (Counterclockwise)

Preceding gene: 238895456

Following gene: 238895454

Centisome position: 63.68

GC content: 60.08

Gene sequence:

>789_bases
GTGGATAACCAGATATCTGTACCGCCTGCGCTAACCGGAAACTACGCTTTTTTCTTTGACCTCGACGGTACTCTTGCCGA
TATCCAGCCGCACCCCGATCAGGTGGTGATACCCGACAGCACGCTGCAGGCGCTCAATGCGCTGGCCCAGCAGCAGGGGG
GCGCGGTGGCATTGATTTCAGGGCGCTCAATGGCTGAACTTGACGCGCTAACCCATCCCTGGCGGCTACCGCTGGCCGGC
GTTCACGGGGCCGAGCGCCGTGATATCAATGGTAAAACCTACATCGTCTCTCTGCCGACAGCGCTGCGCGATGAGATCGC
GGCTGAGCTGACGTCGGCGCTGGAAGCGCTCCCGGGATGTGAGCTGGAGAGTAAAGAGATGGCTTTCGCGCTCCACTATC
GCCAGGCCCCGCAGCAGCAGAGCGCCGTGCTGGAGCTGGCGCAGCGGATTGTTCAGCGCTATCCGCTGCTGGCGTTACAG
CTTGGCAAGTGCGTGGTGGAGATTAAACCCCGCGGCGTCAACAAAGGGGAGGCGATTACCGCGTTCATGCAGGAGGCACC
ATTCGCCGGCCGCGAACCGGTTTTTGTCGGCGATGATTTGACCGACGAGGCGGGATTCAGCGTCGTTAATCAACTGCAGG
GAATGTCGGTAAAAGTTGGCGCCGGGGAAACTCAGGCGCATTGGCGGTTGGCGGATGCCGCCGCTGTAAGGACGTGGTTG
CAACATCTGGCGTATGACGCGCAAACCGAAAGGAGGGATGACCATGAGTCGTTTAGTCGTAGTCTCTAA

Upstream 100 bases:

>100_bases
AACTATCAAAAATGGCGAGGTTGGTCACACTGTCTATACTTACATGGCTCACATATAATTAACAACCAGCTTCGGCTGGC
CATGATAAGGAGGAAACAGG

Downstream 100 bases:

>100_bases
CCGTATCGCCTTACCGGACGATAAAAAATCGAGCGCTGGCGGTCTGGCCGTCGGCATCCTGGGGGCACTGAGAGCGGCGG
GGGGTCTGTGGTTTGGCTGG

Product: trehalose-6-phosphate phosphatase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MDNQISVPPALTGNYAFFFDLDGTLADIQPHPDQVVIPDSTLQALNALAQQQGGAVALISGRSMAELDALTHPWRLPLAG
VHGAERRDINGKTYIVSLPTALRDEIAAELTSALEALPGCELESKEMAFALHYRQAPQQQSAVLELAQRIVQRYPLLALQ
LGKCVVEIKPRGVNKGEAITAFMQEAPFAGREPVFVGDDLTDEAGFSVVNQLQGMSVKVGAGETQAHWRLADAAAVRTWL
QHLAYDAQTERRDDHESFSRSL

Sequences:

>Translated_262_residues
MDNQISVPPALTGNYAFFFDLDGTLADIQPHPDQVVIPDSTLQALNALAQQQGGAVALISGRSMAELDALTHPWRLPLAG
VHGAERRDINGKTYIVSLPTALRDEIAAELTSALEALPGCELESKEMAFALHYRQAPQQQSAVLELAQRIVQRYPLLALQ
LGKCVVEIKPRGVNKGEAITAFMQEAPFAGREPVFVGDDLTDEAGFSVVNQLQGMSVKVGAGETQAHWRLADAAAVRTWL
QHLAYDAQTERRDDHESFSRSL
>Mature_262_residues
MDNQISVPPALTGNYAFFFDLDGTLADIQPHPDQVVIPDSTLQALNALAQQQGGAVALISGRSMAELDALTHPWRLPLAG
VHGAERRDINGKTYIVSLPTALRDEIAAELTSALEALPGCELESKEMAFALHYRQAPQQQSAVLELAQRIVQRYPLLALQ
LGKCVVEIKPRGVNKGEAITAFMQEAPFAGREPVFVGDDLTDEAGFSVVNQLQGMSVKVGAGETQAHWRLADAAAVRTWL
QHLAYDAQTERRDDHESFSRSL

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=266, Percent_Identity=63.1578947368421, Blast_Score=344, Evalue=3e-96,
Organism=Drosophila melanogaster, GI19920676, Length=241, Percent_Identity=28.2157676348548, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221473368, Length=244, Percent_Identity=28.6885245901639, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129307, Length=244, Percent_Identity=28.6885245901639, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582490, Length=244, Percent_Identity=28.6885245901639, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 28537; Mature: 28537

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQISVPPALTGNYAFFFDLDGTLADIQPHPDQVVIPDSTLQALNALAQQQGGAVALIS
CCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEC
GRSMAELDALTHPWRLPLAGVHGAERRDINGKTYIVSLPTALRDEIAAELTSALEALPGC
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
ELESKEMAFALHYRQAPQQQSAVLELAQRIVQRYPLLALQLGKCVVEIKPRGVNKGEAIT
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHEECCCEEEEEECCCCCCCHHHH
AFMQEAPFAGREPVFVGDDLTDEAGFSVVNQLQGMSVKVGAGETQAHWRLADAAAVRTWL
HHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHEEHHHHHHHHHHH
QHLAYDAQTERRDDHESFSRSL
HHHHHCCHHHCCCHHHHHHCCC
>Mature Secondary Structure
MDNQISVPPALTGNYAFFFDLDGTLADIQPHPDQVVIPDSTLQALNALAQQQGGAVALIS
CCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCEEEECCHHHHHHHHHHHHCCCEEEEEC
GRSMAELDALTHPWRLPLAGVHGAERRDINGKTYIVSLPTALRDEIAAELTSALEALPGC
CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCC
ELESKEMAFALHYRQAPQQQSAVLELAQRIVQRYPLLALQLGKCVVEIKPRGVNKGEAIT
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHEECCCEEEEEECCCCCCCHHHH
AFMQEAPFAGREPVFVGDDLTDEAGFSVVNQLQGMSVKVGAGETQAHWRLADAAAVRTWL
HHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHEEHHHHHHHHHHH
QHLAYDAQTERRDDHESFSRSL
HHHHHCCHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]