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The map label for this gene is fadR [H]

Identifier: 238895370

GI number: 238895370

Start: 3258333

End: 3259127

Strand: Reverse

Name: fadR [H]

Synonym: KP1_3435

Alternate gene names: 238895370

Gene position: 3259127-3258333 (Counterclockwise)

Preceding gene: 238895374

Following gene: 238895368

Centisome position: 62.1

GC content: 55.97

Gene sequence:

>795_bases
TTGCCATGCTATCTGCGCTATAGCGGCTCTGGTATGATGAGTGCAATTGTAACGCTGTGTAATGGAAATCTTACTATGGT
CATTAAGGCGCAGAGCCCTGCGGGTTTCGCGGAAGAGTACATCATTGAGAGTATCTGGAATAACCGCTTCCCTCCCGGAT
CGATTCTCCCCGCTGAACGCGAGCTTTCTGAGCTGATCGGTGTCACCCGCACAACCCTGCGCGAAGTATTGCAGCGTCTG
GCCCGTGACGGCTGGCTGACCATTCAGCATGGTAAGCCCACTAAAGTGAATAACTTTTGGGAAACCTCCGGCCTGAATAT
CCTCGAAACGCTGGCGCGCCTCGATCACGACAGCGTACCGCAGCTGATTGATAATCTGCTCTCCGTGCGCACCAACATTT
CCACGATTTTTATCCGCACCGCGTTTCGCCAGCATCCGGATAAAGCGCTGGCGGTCCTGGACAGCGCCCGGGAGGTGGAG
GATCACGCCGACGCCTTCGCCGAGCTTGATTATAATATTTTCCGTGGTCTGGCGTTCGCCTCCGGCAACCCGATCTACGG
TCTGATCCTCAACGGCATGAAGGGGTTGTATACCCGCATCGGCCGCCACTATTTCTCCAGCCCGGAAGCGCGCAGCCTGG
CGCTCGGTTTCTATCATCAGCTGGCGAAAGTGTGTGAGGCTGGCCTGCATGACCAGGTTTACGAGCTGGTTCGTCGCTAC
GGCCATGACAGCGGCGAGATCTGGCACCGGATGCAGAAATCGCTGCCCGGTGATTTAGCCATGAATATGCGTTAA

Upstream 100 bases:

>100_bases
TGAGAAGCAACTTTCTTCGCGCCGCGCTGGCGGTTTGTGAAGATAAGGAAAAGCGCAAAGTAAAAGCGGAAAATGAAACG
GCGATCCCTTTTTAATTCAC

Downstream 100 bases:

>100_bases
GCGGGCTTTTCGCGATCGATATACAGAACAAGGGGGCCAATGGCCCCCTTTGTTATTTTACTCGCCCCGCAATGCTATAG
CGCGTTCGGCCGCGCCGGGC

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPCYLRYSGSGMMSAIVTLCNGNLTMVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRL
ARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVPQLIDNLLSVRTNISTIFIRTAFRQHPDKALAVLDSAREVE
DHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFSSPEARSLALGFYHQLAKVCEAGLHDQVYELVRRY
GHDSGEIWHRMQKSLPGDLAMNMR

Sequences:

>Translated_264_residues
MPCYLRYSGSGMMSAIVTLCNGNLTMVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRL
ARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVPQLIDNLLSVRTNISTIFIRTAFRQHPDKALAVLDSAREVE
DHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFSSPEARSLALGFYHQLAKVCEAGLHDQVYELVRRY
GHDSGEIWHRMQKSLPGDLAMNMR
>Mature_263_residues
PCYLRYSGSGMMSAIVTLCNGNLTMVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLA
RDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVPQLIDNLLSVRTNISTIFIRTAFRQHPDKALAVLDSAREVED
HADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFSSPEARSLALGFYHQLAKVCEAGLHDQVYELVRRYG
HDSGEIWHRMQKSLPGDLAMNMR

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=239, Percent_Identity=90.3765690376569, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29754; Mature: 29623

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPCYLRYSGSGMMSAIVTLCNGNLTMVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAER
CCCEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHH
ELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVP
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCHH
QLIDNLLSVRTNISTIFIRTAFRQHPDKALAVLDSAREVEDHADAFAELDYNIFRGLAFA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGNPIYGLILNGMKGLYTRIGRHYFSSPEARSLALGFYHQLAKVCEAGLHDQVYELVRRY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GHDSGEIWHRMQKSLPGDLAMNMR
CCCHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PCYLRYSGSGMMSAIVTLCNGNLTMVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAER
CCEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCHH
ELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVP
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCHH
QLIDNLLSVRTNISTIFIRTAFRQHPDKALAVLDSAREVEDHADAFAELDYNIFRGLAFA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGNPIYGLILNGMKGLYTRIGRHYFSSPEARSLALGFYHQLAKVCEAGLHDQVYELVRRY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GHDSGEIWHRMQKSLPGDLAMNMR
CCCHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA