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The map label for this gene is alr [H]

Identifier: 238895366

GI number: 238895366

Start: 3254026

End: 3255096

Strand: Reverse

Name: alr [H]

Synonym: KP1_3431

Alternate gene names: 238895366

Gene position: 3255096-3254026 (Counterclockwise)

Preceding gene: 238895367

Following gene: 238895363

Centisome position: 62.02

GC content: 65.27

Gene sequence:

>1071_bases
ATGACCCGTCCGGTAGTGGCCAGCATCGACCTGCTGGCCTTGCGGCAGAATTTACAGATAGTGCGTCGCGCGGCCCCCGG
GTCGCGCCTGTGGGCGGTGGTCAAGGCCAACGCCTACGGTCACGGCGTGGCGCGCGTATGGAGTGCGTTAAGCGCGGCGG
ATGGTTTCGCCTTGCTCAACCTGGAAGAGGCGATCCTGCTGCGCGAGCAGGGCTGGAAAGGCCCGATCCTGCTGCTGGAG
GGCTTCTTCCATGCCGATGAGCTGGCGGTGCTGGATCAATATCGTTTAACCACCAGCGTCCACAGCAACTGGCAGATTAA
GGCCCTGCAACAGGCGAAGCTGCGCGCGCCGCTGGATATCTATCTCAAGGTGAACAGCGGCATGAACCGGCTGGGCTTTA
TGCCTGAGCGGGTCCACACCGTCTGGCAGCAGCTGCGGGCGATAAGCAACGTCGGCGAGATGACGCTGATGTCGCACTTC
GCGGAGGCGGAGAACCCGCAGGGAATTGTCGAGCCGATGCGCCGTATCGAACAGGCGGCGGAGGGGCTGGATTGCCCGCG
CTCGCTGGCCAACTCGGCGGCGACCCTCTGGCATCCGGAAGCGCATTTTGACTGGGTTCGTCCAGGCATCGTGCTGTATG
GCGCGTCGCCTTCCGGGCAGTGGCAGGACATCGCCAACACCGGGCTGAAGCCGGTGATGACGCTGCGCAGCGAGATTATC
GGCGTGCAGAACCTGCGCCCCGGCGAGGCGATTGGCTATGGCGGCCTGTACCGCACCACCCAGGAGCAGCGGATCGGCAT
CGTCGCCTGCGGCTATGCCGATGGCTATCCGCGGGTGGCGCCGAGCGGCACGCCGGTGCTGGTGGATGGCGTACGTACCA
CCACCGTGGGACGCGTGTCGATGGACATGCTGGCGGTCGATTTAACGCCCTGCCCGCAGGCCGGGATCGGCGCGCCGGTC
GAGCTGTGGGGCAAAGAGATTAAAATCGACGACGTGGCGGCCAGCAGCGGCACCGTCGGCTATGAACTGATGTGCGCCCT
GGCGCCGCGGGTGCCAGTTGTGACCCTGTAA

Upstream 100 bases:

>100_bases
GGCGATCCCTTACGACGATCTGGCGGTTGCCCGCTACAGCCCCGGTTTTACCCCGGCGCGCCCGCAGCACCTGCACGGCG
CACACAACTAAGGAGCTTGC

Downstream 100 bases:

>100_bases
CCTATTCCGGGGCGGATCACTCCGCCTCGTCTTCCGCGACCCGCACCCCAACCTTCAGCACGTGATCGTTCTCTTTTTCA
GCTACCGTCCACACCATCCC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTRPVVASIDLLALRQNLQIVRRAAPGSRLWAVVKANAYGHGVARVWSALSAADGFALLNLEEAILLREQGWKGPILLLE
GFFHADELAVLDQYRLTTSVHSNWQIKALQQAKLRAPLDIYLKVNSGMNRLGFMPERVHTVWQQLRAISNVGEMTLMSHF
AEAENPQGIVEPMRRIEQAAEGLDCPRSLANSAATLWHPEAHFDWVRPGIVLYGASPSGQWQDIANTGLKPVMTLRSEII
GVQNLRPGEAIGYGGLYRTTQEQRIGIVACGYADGYPRVAPSGTPVLVDGVRTTTVGRVSMDMLAVDLTPCPQAGIGAPV
ELWGKEIKIDDVAASSGTVGYELMCALAPRVPVVTL

Sequences:

>Translated_356_residues
MTRPVVASIDLLALRQNLQIVRRAAPGSRLWAVVKANAYGHGVARVWSALSAADGFALLNLEEAILLREQGWKGPILLLE
GFFHADELAVLDQYRLTTSVHSNWQIKALQQAKLRAPLDIYLKVNSGMNRLGFMPERVHTVWQQLRAISNVGEMTLMSHF
AEAENPQGIVEPMRRIEQAAEGLDCPRSLANSAATLWHPEAHFDWVRPGIVLYGASPSGQWQDIANTGLKPVMTLRSEII
GVQNLRPGEAIGYGGLYRTTQEQRIGIVACGYADGYPRVAPSGTPVLVDGVRTTTVGRVSMDMLAVDLTPCPQAGIGAPV
ELWGKEIKIDDVAASSGTVGYELMCALAPRVPVVTL
>Mature_355_residues
TRPVVASIDLLALRQNLQIVRRAAPGSRLWAVVKANAYGHGVARVWSALSAADGFALLNLEEAILLREQGWKGPILLLEG
FFHADELAVLDQYRLTTSVHSNWQIKALQQAKLRAPLDIYLKVNSGMNRLGFMPERVHTVWQQLRAISNVGEMTLMSHFA
EAENPQGIVEPMRRIEQAAEGLDCPRSLANSAATLWHPEAHFDWVRPGIVLYGASPSGQWQDIANTGLKPVMTLRSEIIG
VQNLRPGEAIGYGGLYRTTQEQRIGIVACGYADGYPRVAPSGTPVLVDGVRTTTVGRVSMDMLAVDLTPCPQAGIGAPVE
LWGKEIKIDDVAASSGTVGYELMCALAPRVPVVTL

Specific function: Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=356, Percent_Identity=80.3370786516854, Blast_Score=599, Evalue=1e-173,
Organism=Escherichia coli, GI1790487, Length=346, Percent_Identity=44.7976878612717, Blast_Score=291, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38732; Mature: 38601

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPVVASIDLLALRQNLQIVRRAAPGSRLWAVVKANAYGHGVARVWSALSAADGFALLN
CCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEE
LEEAILLREQGWKGPILLLEGFFHADELAVLDQYRLTTSVHSNWQIKALQQAKLRAPLDI
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHECCCCEEEEEHHHHHCCCCEEE
YLKVNSGMNRLGFMPERVHTVWQQLRAISNVGEMTLMSHFAEAENPQGIVEPMRRIEQAA
EEEECCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EGLDCPRSLANSAATLWHPEAHFDWVRPGIVLYGASPSGQWQDIANTGLKPVMTLRSEII
CCCCCHHHHHCCCCEEECCCCCCCEECCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHH
GVQNLRPGEAIGYGGLYRTTQEQRIGIVACGYADGYPRVAPSGTPVLVDGVRTTTVGRVS
CCCCCCCCCCCCCCCCEECCHHHCEEEEEECCCCCCCCCCCCCCEEEEECCEEEEECCEE
MDMLAVDLTPCPQAGIGAPVELWGKEIKIDDVAASSGTVGYELMCALAPRVPVVTL
EEEEEEECCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHEECCCCCCEEEC
>Mature Secondary Structure 
TRPVVASIDLLALRQNLQIVRRAAPGSRLWAVVKANAYGHGVARVWSALSAADGFALLN
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEE
LEEAILLREQGWKGPILLLEGFFHADELAVLDQYRLTTSVHSNWQIKALQQAKLRAPLDI
HHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHECCCCEEEEEHHHHHCCCCEEE
YLKVNSGMNRLGFMPERVHTVWQQLRAISNVGEMTLMSHFAEAENPQGIVEPMRRIEQAA
EEEECCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EGLDCPRSLANSAATLWHPEAHFDWVRPGIVLYGASPSGQWQDIANTGLKPVMTLRSEII
CCCCCHHHHHCCCCEEECCCCCCCEECCCEEEEECCCCCCHHHHHHCCCHHHHHHHHHHH
GVQNLRPGEAIGYGGLYRTTQEQRIGIVACGYADGYPRVAPSGTPVLVDGVRTTTVGRVS
CCCCCCCCCCCCCCCCEECCHHHCEEEEEECCCCCCCCCCCCCCEEEEECCEEEEECCEE
MDMLAVDLTPCPQAGIGAPVELWGKEIKIDDVAASSGTVGYELMCALAPRVPVVTL
EEEEEEECCCCCCCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHEECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457858 [H]