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The map label for this gene is hemA [H]

Identifier: 238895296

GI number: 238895296

Start: 3179364

End: 3180620

Strand: Reverse

Name: hemA [H]

Synonym: KP1_3350

Alternate gene names: 238895296

Gene position: 3180620-3179364 (Counterclockwise)

Preceding gene: 238895301

Following gene: 238895295

Centisome position: 60.6

GC content: 60.54

Gene sequence:

>1257_bases
ATGACCCTTTTAGCTCTTGGCATCAATCACAAAACAGCTCCGGTCGCCCTGCGAGAACGCGTCACGTTTTCGCCGGAAAC
GCTCGATAAGGCGCTGGAGAGCTTGCTGGCTCAGCCGATGGTGCAGGGTGGGGTGGTGCTGTCGACCTGCAACCGCACGG
AACTCTATCTCAGCGTCGAAGAGCAGGATAACCTGCAGGAAGCGCTGATCCGCTGGCTGTGCAACTACCACGGCCTCAAC
GAAGAAGACCTGCGAAAAAGCCTTTACTGGCATCAGGATAATGACGCCGTCAGCCATCTGATGCGCGTCGCCAGCGGCCT
CGATTCGCTGGTGCTGGGCGAGCCGCAGATCCTCGGCCAGGTGAAAAAAGCCTTCGCCGACTCCAGCCGCGGCCATCTTA
ACGTCAGCGAGCTGGAGCGGATGTTCCAGAAATCCTTTTCAGTGGCTAAGCGCGTGCGTACCGAAACCGATATCGGCGCC
AGCGCGGTCTCTGTGGCTTTCGCCGCCTGTACCCTGGCGCGGCAAATCTTTGAATCGCTCTCCAGCGTCACCGTGTTACT
GGTCGGCGCCGGTGAAACCATTGAGCTGGTAGCGCGCCATCTTCGCGAACATCACGTGCGCAAAATGGTGATCGCCAACC
GCACCCGTGAACGCGCCCAGGCGCTGGCGGAGGAAGTGGGCGCCGAGGTGATAGCCCTCAGCGATATCGACGAACGGCTG
AAAGAGGCCGACATCATTATCAGCTCCACCGCCAGCCCGCTGCCGATCATCGGCAAAGGCATGGTGGAGCGTGCGCTTAA
GGCGCGGCGTAACCAGCCGATGCTGCTGGTGGATATCGCCGTCCCGCGCGACGTTGAACCAGAGGTCGGCAAACTGGCTA
ACGCCTACCTCTACAGCGTCGACGATTTGCAAAACATCATTCAGCATAACCTGGCGCAGCGTAAGGCTGCCGCGGTGCAG
GCCGAATCGATCGTCGAGCAGGAAACCAGCGAATTTATGGCCTGGCTGCGCGCGCAGAGCGCCAGCGAGACCATTCGCGA
ATACCGTTCTCAGTCTGAGCAGGTCCGTGAGGAGCTGACGGCGAAAGCGCTGGCCGCGCTGGAGCAGGGCGGTGATGCCC
AGGAAATTATGCAGGATCTGGCGCGCAAGCTCACTAACCGCCTGATCCACGCGCCAACCAAATCTCTTCAGCAGGCCGCC
CGTGACGGGGACGACGAACGTCTGCATATTCTGCGCAACAGCCTCGGGCTGGAATAG

Upstream 100 bases:

>100_bases
AACTATTACTCCAAAAGGGGAGCCTCTCTTTTATTGATTACGCGCATCCTGTATGATGCACTCAGACTAACCTTAGCAAC
GCTGGTACTACTCCCTCACA

Downstream 100 bases:

>100_bases
CGCACCTTTCTCTTATTTTCAGGACAGGGTGAATTCACGCCTATGAAGTCTTCTATTGTTGCCAAACTGGAAGCGTTGTA
CGAGCGCCATGAAGAAGTGC

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTLLALGINHKTAPVALRERVTFSPETLDKALESLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCNYHGLN
EEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSSRGHLNVSELERMFQKSFSVAKRVRTETDIGA
SAVSVAFAACTLARQIFESLSSVTVLLVGAGETIELVARHLREHHVRKMVIANRTRERAQALAEEVGAEVIALSDIDERL
KEADIIISSTASPLPIIGKGMVERALKARRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQNIIQHNLAQRKAAAVQ
AESIVEQETSEFMAWLRAQSASETIREYRSQSEQVREELTAKALAALEQGGDAQEIMQDLARKLTNRLIHAPTKSLQQAA
RDGDDERLHILRNSLGLE

Sequences:

>Translated_418_residues
MTLLALGINHKTAPVALRERVTFSPETLDKALESLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCNYHGLN
EEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSSRGHLNVSELERMFQKSFSVAKRVRTETDIGA
SAVSVAFAACTLARQIFESLSSVTVLLVGAGETIELVARHLREHHVRKMVIANRTRERAQALAEEVGAEVIALSDIDERL
KEADIIISSTASPLPIIGKGMVERALKARRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQNIIQHNLAQRKAAAVQ
AESIVEQETSEFMAWLRAQSASETIREYRSQSEQVREELTAKALAALEQGGDAQEIMQDLARKLTNRLIHAPTKSLQQAA
RDGDDERLHILRNSLGLE
>Mature_417_residues
TLLALGINHKTAPVALRERVTFSPETLDKALESLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCNYHGLNE
EDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSSRGHLNVSELERMFQKSFSVAKRVRTETDIGAS
AVSVAFAACTLARQIFESLSSVTVLLVGAGETIELVARHLREHHVRKMVIANRTRERAQALAEEVGAEVIALSDIDERLK
EADIIISSTASPLPIIGKGMVERALKARRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQNIIQHNLAQRKAAAVQA
ESIVEQETSEFMAWLRAQSASETIREYRSQSEQVREELTAKALAALEQGGDAQEIMQDLARKLTNRLIHAPTKSLQQAAR
DGDDERLHILRNSLGLE

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=418, Percent_Identity=92.1052631578947, Blast_Score=768, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR003462
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 46360; Mature: 46229

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLALGINHKTAPVALRERVTFSPETLDKALESLLAQPMVQGGVVLSTCNRTELYLSVE
CEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEEC
EQDNLQEALIRWLCNYHGLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQ
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHH
VKKAFADSSRGHLNVSELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SSVTVLLVGAGETIELVARHLREHHVRKMVIANRTRERAQALAEEVGAEVIALSDIDERL
HHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
KEADIIISSTASPLPIIGKGMVERALKARRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
HHHCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
DDLQNIIQHNLAQRKAAAVQAESIVEQETSEFMAWLRAQSASETIREYRSQSEQVREELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKALAALEQGGDAQEIMQDLARKLTNRLIHAPTKSLQQAARDGDDERLHILRNSLGLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLLALGINHKTAPVALRERVTFSPETLDKALESLLAQPMVQGGVVLSTCNRTELYLSVE
EEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEEEC
EQDNLQEALIRWLCNYHGLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQ
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCHHHHHH
VKKAFADSSRGHLNVSELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
SSVTVLLVGAGETIELVARHLREHHVRKMVIANRTRERAQALAEEVGAEVIALSDIDERL
HHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHH
KEADIIISSTASPLPIIGKGMVERALKARRNQPMLLVDIAVPRDVEPEVGKLANAYLYSV
HHHCEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
DDLQNIIQHNLAQRKAAAVQAESIVEQETSEFMAWLRAQSASETIREYRSQSEQVREELT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKALAALEQGGDAQEIMQDLARKLTNRLIHAPTKSLQQAARDGDDERLHILRNSLGLE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA