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The map label for this gene is infC [H]

Identifier: 238895234

GI number: 238895234

Start: 3115710

End: 3116144

Strand: Reverse

Name: infC [H]

Synonym: KP1_3284

Alternate gene names: 238895234

Gene position: 3116144-3115710 (Counterclockwise)

Preceding gene: 238895235

Following gene: 238895233

Centisome position: 59.37

GC content: 48.28

Gene sequence:

>435_bases
GTGAGTCTGAGAGAAGCTATCGAAAAGGCTGAAGAGGCTGGAGTAGATTTAGTTGAAATCAGCCCTAACGCCGAGCCGCC
AGTTTGTCGTATCATGGACTACGGCAAGTTCCTTTATGAAAAGAGTAAGTCTTCTAAGGAACAGAAGAAGAAGCAGAAAG
TTATCCAGGTTAAGGAAATTAAATTCCGCCCTGGTACTGATGAAGGTGACTATCAGGTAAAACTCCGCAGCCTGATTCGC
TTTCTCGAAGATGGCGATAAGGCCAAGATCACGCTGCGTTTCCGCGGTCGTGAGATGGCCCACCAGCAGATCGGTATGGA
AGTGCTTAACCGCGTGAAAGACGATCTGGTTGAACTGGCAGTAGTCGAATCCTTCCCAACGAAGATCGAAGGCCGCCAGA
TGATCATGGTGCTCGCTCCTAAGAAGAAACAGTAA

Upstream 100 bases:

>100_bases
CGGAAAACGAGTTCAAACGGCACGTCCGAATCGTATTAATGGCGAGATTCGCGCCCAGGAAGTTCGCTTAACAGGTCTGG
AAGGTGAGCAGCTGGGAATT

Downstream 100 bases:

>100_bases
GGCCATCAAGAAACATTTCCGGTGGGCTTTGGCTCACTGGTTTTGTTCGCCTTTGTTTCGTTTATTAACAATGCGAAGTG
GAAGTTATTAAAATGCCAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MSLREAIEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIR
FLEDGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLVELAVVESFPTKIEGRQMIMVLAPKKKQ

Sequences:

>Translated_144_residues
MSLREAIEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIR
FLEDGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLVELAVVESFPTKIEGRQMIMVLAPKKKQ
>Mature_143_residues
SLREAIEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRF
LEDGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLVELAVVESFPTKIEGRQMIMVLAPKKKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=144, Percent_Identity=97.2222222222222, Blast_Score=254, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 16595; Mature: 16463

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLREAIEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEI
CCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHE
KFRPGTDEGDYQVKLRSLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLVELA
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VVESFPTKIEGRQMIMVLAPKKKQ
HHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SLREAIEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEI
CHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHE
KFRPGTDEGDYQVKLRSLIRFLEDGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLVELA
EECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
VVESFPTKIEGRQMIMVLAPKKKQ
HHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8405963 [H]