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The map label for this gene is aroH [H]

Identifier: 238895217

GI number: 238895217

Start: 3099687

End: 3100733

Strand: Direct

Name: aroH [H]

Synonym: KP1_3265

Alternate gene names: 238895217

Gene position: 3099687-3100733 (Clockwise)

Preceding gene: 238895216

Following gene: 238895218

Centisome position: 59.06

GC content: 62.18

Gene sequence:

>1047_bases
ATGAATAAAACAGACGAATTGCGTACCGCGCGCATTGAGAGCCTGGTAACGCCCGCGGAGCTGGCCCAGCGCCATCCCGT
GACGGCCGACGTGGCTGCCCACGTCTCGGCCTCCCGCCGCCGAATTGAAAAAATCCTCAACGGCGAAGACCGCCGACTGC
TGGTGATTATCGGCCCCTGCTCCATTCACGACACCGACGCGGCGCTGGAGTATGCCCGCCGCCTGCAGGGCATGCGCGAG
CGCTACCAGCCGCAGCTGGAGATCGTGATGCGCACCTACTTTGAAAAACCGCGTACCGTGGTGGGCTGGAAAGGCTTAAT
CTCCGATCCCGACCTCAACGGCAGCTACCGGGTCAACCACGGAATTGAGCTGGCGCGGCGCCTGCTGCTGCAGGTTAATG
AGCTGGGGGTACCGACGGCCACCGAGTTTCTCGATATGGTGACCGGTCAGTTTATCGCCGATCTCATCAGCTGGGGGGCC
ATCGGGGCGCGCACCACTGAAAGCCAGATCCACCGTGAAATGGCCTCAGCGCTCTCCTGCCCGGTTGGATTTAAAAACGG
CACCGACGGCAATACGCGCATCGCGGTGGACGCCATCCGCGCCTCCCGCGCCAGCCATATGTTCCTCTCTCCGGACAAGC
AGGGGCAGATGACGATTTACCAGACCAGCGGCAACCCGTACGGGCACATCATTATGCGCGGCGGCAAACGGCCAAACTAT
CACGCCGAGGATATCGCCGCCGCCGGCGAGGCGCTACGTGAATTCGATCTGCCGGAACAGCTGGTCGTTGATTTCAGCCA
TGGCAACTGCCAGAAGCAGCACCGCCGTCAGCTGGAAGTGTGCGCCGATATCTGTCAGCAAATTCGCGCGGGCTCTACCG
CCATCGCCGGGATTATGGCAGAGAGCTTCCTGCAGGAAGGCACTCAGAAAGTGGTCCCCGGCCAGCCGCTGACCTGGGGC
CAGTCGATCACCGACCCCTGCCTGAGCTGGGAAGACAGCGAAAGATTATTGAGCGAGCTGGCTGCGGCCACCGCCACACG
CCTGTAA

Upstream 100 bases:

>100_bases
GATCATGCCCTGCTCTTGCAATAAGCAGGGATTGGTTTATCGTGATGCGCATCACTTCCCGGCATTTTCGCCGCGGAAGA
AACAGATTTTTGAGACCCCA

Downstream 100 bases:

>100_bases
CCGCTCCGCCCGCCGCGCCTGCGGCGGGCAATTCTCTTCGCTGACTCCCCTACCAAATCCGGTAACACGATAAATAACGC
TTGCCGTCAAAAACAACATT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MNKTDELRTARIESLVTPAELAQRHPVTADVAAHVSASRRRIEKILNGEDRRLLVIIGPCSIHDTDAALEYARRLQGMRE
RYQPQLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGIELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKQGQMTIYQTSGNPYGHIIMRGGKRPNY
HAEDIAAAGEALREFDLPEQLVVDFSHGNCQKQHRRQLEVCADICQQIRAGSTAIAGIMAESFLQEGTQKVVPGQPLTWG
QSITDPCLSWEDSERLLSELAAATATRL

Sequences:

>Translated_348_residues
MNKTDELRTARIESLVTPAELAQRHPVTADVAAHVSASRRRIEKILNGEDRRLLVIIGPCSIHDTDAALEYARRLQGMRE
RYQPQLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGIELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKQGQMTIYQTSGNPYGHIIMRGGKRPNY
HAEDIAAAGEALREFDLPEQLVVDFSHGNCQKQHRRQLEVCADICQQIRAGSTAIAGIMAESFLQEGTQKVVPGQPLTWG
QSITDPCLSWEDSERLLSELAAATATRL
>Mature_348_residues
MNKTDELRTARIESLVTPAELAQRHPVTADVAAHVSASRRRIEKILNGEDRRLLVIIGPCSIHDTDAALEYARRLQGMRE
RYQPQLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNHGIELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKQGQMTIYQTSGNPYGHIIMRGGKRPNY
HAEDIAAAGEALREFDLPEQLVVDFSHGNCQKQHRRQLEVCADICQQIRAGSTAIAGIMAESFLQEGTQKVVPGQPLTWG
QSITDPCLSWEDSERLLSELAAATATRL

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787996, Length=348, Percent_Identity=86.7816091954023, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1786969, Length=345, Percent_Identity=55.9420289855072, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1788953, Length=327, Percent_Identity=48.9296636085627, Blast_Score=333, Evalue=9e-93,
Organism=Saccharomyces cerevisiae, GI6319726, Length=350, Percent_Identity=45.7142857142857, Blast_Score=314, Evalue=1e-86,
Organism=Saccharomyces cerevisiae, GI6320240, Length=353, Percent_Identity=41.0764872521246, Blast_Score=287, Evalue=2e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38555; Mature: 38555

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTDELRTARIESLVTPAELAQRHPVTADVAAHVSASRRRIEKILNGEDRRLLVIIGPC
CCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
SIHDTDAALEYARRLQGMRERYQPQLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH
GIELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKQGQMTIYQTSGNPYGHIIMRGGKRPNY
CCCCCCCCCCCCEEEEEHHHHHCCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
HAEDIAAAGEALREFDLPEQLVVDFSHGNCQKQHRRQLEVCADICQQIRAGSTAIAGIMA
CHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLQEGTQKVVPGQPLTWGQSITDPCLSWEDSERLLSELAAATATRL
HHHHHHCHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKTDELRTARIESLVTPAELAQRHPVTADVAAHVSASRRRIEKILNGEDRRLLVIIGPC
CCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
SIHDTDAALEYARRLQGMRERYQPQLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRVNH
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEECH
GIELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGAIGARTTESQIHREMASALSC
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
PVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKQGQMTIYQTSGNPYGHIIMRGGKRPNY
CCCCCCCCCCCCEEEEEHHHHHCCCCEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCC
HAEDIAAAGEALREFDLPEQLVVDFSHGNCQKQHRRQLEVCADICQQIRAGSTAIAGIMA
CHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ESFLQEGTQKVVPGQPLTWGQSITDPCLSWEDSERLLSELAAATATRL
HHHHHHCHHHCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]