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The map label for this gene is fecD [H]

Identifier: 238895202

GI number: 238895202

Start: 3084196

End: 3085233

Strand: Direct

Name: fecD [H]

Synonym: KP1_3248

Alternate gene names: 238895202

Gene position: 3084196-3085233 (Clockwise)

Preceding gene: 238895201

Following gene: 238895203

Centisome position: 58.76

GC content: 64.16

Gene sequence:

>1038_bases
ATGAGCGTCGCCGTGCTTCAGACGCGCCGCAGCATGCTGCTCACCGGCTGGTGTTTACTGGCAGCGATCGTGCTGGCGCT
GGTGATAGCGGTGGGCGTCAGCGTCGGCGAGCTGGCCATCCCGCTGCAGAATGTCTTTTACGCTATCAGCAACAGAACCG
GCTTAACCGCTGAGCCTCTCAACCGTATCTATGAGAGCGTAATCTGGGATTTCCGCCTCAGCCGCGCGCTGGTCGCCGCC
TGCTGCGGCGCCGGCCTCGCTATCTGCGGCGTCGTGCTGCAAAGCCTGCTGAAAAATGCCCTCGCGGAACCCTACGTCCT
CGGCGTCTCCGCCGGGGCCTCCACCGGCGCGGTGTCGATCGTGGTGCTGGGCCTTGGCGCTGGCGCAATTTCCCTCTCGG
CCGGGGCCTTTGCCGGGGCCTTCGCCGCCTTCGCCTTTGTCGCCTTGCTGACTAACGGCGCGCGCGGCGGCAATGAGCGT
ACGATTCTTGCGGGCGTCGCCGCCTCGCAGTTATTTAACGCCATCACGGCCTATACCATCAGCACCTCCGCCAGCGCGCA
GCAGGCGCGCGATGTGATGTTCTGGCTGCTGGGCAGCTTCAGCGGCGTTCGCTGGCCCGAATTCCAGTTGGTCATTGTGG
TGGTGCTCGCGGGTCTGGCGGTCTGCCTGTGGTATGCCCGGGCGCTGGACGCGTTCACCTTCGGCGACGATGCCGCCGCC
TCGCTGGGGATTGCTGTGCCGCGCGTGCGCCTGATCCTCTTCACCACTGCGGCGCTGATCACCGCCACCATCGTCAGCAT
GGCCGGCTCAATCGGCTTTGTTGGCCTGGTGGTGCCGCACGTAATGCGTTTCTTCTTTGGCCCGCTGCACCGAACGTTGC
TGATCGCCAGCGCGCTGGCAGGGGCGATATTGATGGTACTGGCGGACATTGCGTCGCGCCTGCTGATTGCCCCGCAAAGT
CTGCCCGTTGGGGTAGTAACCGCCCTGGTTGGGGTACCTTTCTTTGCCGTGATTATCTACCGCTCAAGGAATAAGTGA

Upstream 100 bases:

>100_bases
ATATCGTGGTCATGGACGGTCAGGCGATGAATCCGACCATCCGCACGCTTTACGGCGCGGAACAGGTGGGCGAGCAGCTG
AGAAAAATGGAGCTGAACTG

Downstream 100 bases:

>100_bases
TGAGTATTTGCGCTGAAAATATCACCTGGAAGGCAGGCAAAAAGGTCATCGTCAATAATGTCTCGCTGCGGGTGCCGCGC
GGCGAAACGGTCGGACTGCT

Product: iron(III) dicitrate transport system permease component

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSVAVLQTRRSMLLTGWCLLAAIVLALVIAVGVSVGELAIPLQNVFYAISNRTGLTAEPLNRIYESVIWDFRLSRALVAA
CCGAGLAICGVVLQSLLKNALAEPYVLGVSAGASTGAVSIVVLGLGAGAISLSAGAFAGAFAAFAFVALLTNGARGGNER
TILAGVAASQLFNAITAYTISTSASAQQARDVMFWLLGSFSGVRWPEFQLVIVVVLAGLAVCLWYARALDAFTFGDDAAA
SLGIAVPRVRLILFTTAALITATIVSMAGSIGFVGLVVPHVMRFFFGPLHRTLLIASALAGAILMVLADIASRLLIAPQS
LPVGVVTALVGVPFFAVIIYRSRNK

Sequences:

>Translated_345_residues
MSVAVLQTRRSMLLTGWCLLAAIVLALVIAVGVSVGELAIPLQNVFYAISNRTGLTAEPLNRIYESVIWDFRLSRALVAA
CCGAGLAICGVVLQSLLKNALAEPYVLGVSAGASTGAVSIVVLGLGAGAISLSAGAFAGAFAAFAFVALLTNGARGGNER
TILAGVAASQLFNAITAYTISTSASAQQARDVMFWLLGSFSGVRWPEFQLVIVVVLAGLAVCLWYARALDAFTFGDDAAA
SLGIAVPRVRLILFTTAALITATIVSMAGSIGFVGLVVPHVMRFFFGPLHRTLLIASALAGAILMVLADIASRLLIAPQS
LPVGVVTALVGVPFFAVIIYRSRNK
>Mature_344_residues
SVAVLQTRRSMLLTGWCLLAAIVLALVIAVGVSVGELAIPLQNVFYAISNRTGLTAEPLNRIYESVIWDFRLSRALVAAC
CGAGLAICGVVLQSLLKNALAEPYVLGVSAGASTGAVSIVVLGLGAGAISLSAGAFAGAFAAFAFVALLTNGARGGNERT
ILAGVAASQLFNAITAYTISTSASAQQARDVMFWLLGSFSGVRWPEFQLVIVVVLAGLAVCLWYARALDAFTFGDDAAAS
LGIAVPRVRLILFTTAALITATIVSMAGSIGFVGLVVPHVMRFFFGPLHRTLLIASALAGAILMVLADIASRLLIAPQSL
PVGVVTALVGVPFFAVIIYRSRNK

Specific function: Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=36.4285714285714, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788004, Length=279, Percent_Identity=36.9175627240143, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790741, Length=284, Percent_Identity=35.2112676056338, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1786805, Length=285, Percent_Identity=34.0350877192982, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786804, Length=346, Percent_Identity=32.9479768786127, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786347, Length=284, Percent_Identity=32.3943661971831, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35715; Mature: 35584

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAVLQTRRSMLLTGWCLLAAIVLALVIAVGVSVGELAIPLQNVFYAISNRTGLTAEPL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
NRIYESVIWDFRLSRALVAACCGAGLAICGVVLQSLLKNALAEPYVLGVSAGASTGAVSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEE
VVLGLGAGAISLSAGAFAGAFAAFAFVALLTNGARGGNERTILAGVAASQLFNAITAYTI
EEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHE
STSASAQQARDVMFWLLGSFSGVRWPEFQLVIVVVLAGLAVCLWYARALDAFTFGDDAAA
ECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SLGIAVPRVRLILFTTAALITATIVSMAGSIGFVGLVVPHVMRFFFGPLHRTLLIASALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAILMVLADIASRLLIAPQSLPVGVVTALVGVPFFAVIIYRSRNK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVAVLQTRRSMLLTGWCLLAAIVLALVIAVGVSVGELAIPLQNVFYAISNRTGLTAEPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
NRIYESVIWDFRLSRALVAACCGAGLAICGVVLQSLLKNALAEPYVLGVSAGASTGAVSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEE
VVLGLGAGAISLSAGAFAGAFAAFAFVALLTNGARGGNERTILAGVAASQLFNAITAYTI
EEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHE
STSASAQQARDVMFWLLGSFSGVRWPEFQLVIVVVLAGLAVCLWYARALDAFTFGDDAAA
ECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
SLGIAVPRVRLILFTTAALITATIVSMAGSIGFVGLVVPHVMRFFFGPLHRTLLIASALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAILMVLADIASRLLIAPQSLPVGVVTALVGVPFFAVIIYRSRNK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]