| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is fepC [C]
Identifier: 238895175
GI number: 238895175
Start: 3056859
End: 3057608
Strand: Direct
Name: fepC [C]
Synonym: KP1_3221
Alternate gene names: 238895175
Gene position: 3056859-3057608 (Clockwise)
Preceding gene: 238895174
Following gene: 238895180
Centisome position: 58.24
GC content: 68.0
Gene sequence:
>750_bases ATGAACAGCTCATTATCGCTGCAAGCGCTACGCTACGGCCACCGTCAGCCGCTCTTCGCCCCGCTCACGCTGGCCTGCCG GCCCGGTGAGATCTGGGCGGTGCTGGGCGCCAATGGCCGGGGAAAAAGTACCCTGCTGGATACCCTGACCGGCGTGTTGC CGCCGCTGGGCGGCGAGATGCAGTGCGAGGGCGGCGTGGCCCTGGTTCCGCAGTCGTTTCGTCCCGCTTTTCGCTGGCGC GTGAGCGATGTGGTGCTGATGGGCCGGGCCCGTCACGTGGATCTCTTTGCCCAGCCGGACGAGGAGGATGCCCGGCGGGT TGAGCAGGCGCTGGCGCAGCTGGGGATTGCCGCCCTGGCCGAAGATGACTTCGGCGCCCTCTCCGGCGGCCAGCAGCAGC TGGTGTTGATTGCCCGCGCGCTGGTCAGCGCCAGCCAGAATATCCTGCTGGATGAGCCCTGCTCGGCGCTGGACCTTGGT AACCAGCAGGTGGTATTGCAGCTGATCGGCGACCTCGCCCACCGCCAGGCGCGCACCGTCCTGTTCACCACCCATGATCC CAACCACGCCCTACAGGTGGCCAGCCATACGCTGCTTCTGCTGCCGGAGGGCCGGTGGCTGGCGGGTGAGACCGCCGACG TACTGAGCGAAACGCATCTCCGGCAAGCGTACGGCCTGCCGGTACGCCTGATCCGCCATGCCGCCTCCGCGTTCCCTCTG CTGGCGCCGGGGTTTACGCTGCGTCGCTGA
Upstream 100 bases:
>100_bases TGACCCAGGCGGAGATCCCGATCGGGATCATCACCGCCCTGCTCGGGGCGCCGCTGTTTACCGTGTTGCTGGTGCAATCC CGACGCCGGAGTACGACCCG
Downstream 100 bases:
>100_bases ACGGCATAAAACCCGCCTGCCGGAGATACCCCTGGCCAACGTCGTCGAGGATAAAGCGATACAGGGCCAGCGCGGCGGGA TCGGCCCTGAGACGCGCCAG
Product: putative ABC transport system ATP-binding component
Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MNSSLSLQALRYGHRQPLFAPLTLACRPGEIWAVLGANGRGKSTLLDTLTGVLPPLGGEMQCEGGVALVPQSFRPAFRWR VSDVVLMGRARHVDLFAQPDEEDARRVEQALAQLGIAALAEDDFGALSGGQQQLVLIARALVSASQNILLDEPCSALDLG NQQVVLQLIGDLAHRQARTVLFTTHDPNHALQVASHTLLLLPEGRWLAGETADVLSETHLRQAYGLPVRLIRHAASAFPL LAPGFTLRR
Sequences:
>Translated_249_residues MNSSLSLQALRYGHRQPLFAPLTLACRPGEIWAVLGANGRGKSTLLDTLTGVLPPLGGEMQCEGGVALVPQSFRPAFRWR VSDVVLMGRARHVDLFAQPDEEDARRVEQALAQLGIAALAEDDFGALSGGQQQLVLIARALVSASQNILLDEPCSALDLG NQQVVLQLIGDLAHRQARTVLFTTHDPNHALQVASHTLLLLPEGRWLAGETADVLSETHLRQAYGLPVRLIRHAASAFPL LAPGFTLRR >Mature_249_residues MNSSLSLQALRYGHRQPLFAPLTLACRPGEIWAVLGANGRGKSTLLDTLTGVLPPLGGEMQCEGGVALVPQSFRPAFRWR VSDVVLMGRARHVDLFAQPDEEDARRVEQALAQLGIAALAEDDFGALSGGQQQLVLIARALVSASQNILLDEPCSALDLG NQQVVLQLIGDLAHRQARTVLFTTHDPNHALQVASHTLLLLPEGRWLAGETADVLSETHLRQAYGLPVRLIRHAASAFPL LAPGFTLRR
Specific function: Part Of The Binding-Protein-Dependent Transport System For Ferric Enterobactin. Probably Responsible For Energy Coupling To The Transport System. [C]
COG id: COG1120
COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components
Gene ontology:
Cell location: Inner Membrane-Associated [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI62526033, Length=198, Percent_Identity=29.2929292929293, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI105990541, Length=188, Percent_Identity=28.7234042553192, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI31657092, Length=238, Percent_Identity=27.3109243697479, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI157502203, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI157502201, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI150417984, Length=199, Percent_Identity=29.6482412060301, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI9665248, Length=195, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI21536376, Length=181, Percent_Identity=26.5193370165746, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI46592978, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI46592964, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI46592915, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI46592956, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI46592971, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI46592898, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1786803, Length=248, Percent_Identity=31.8548387096774, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1786345, Length=237, Percent_Identity=32.9113924050633, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1786975, Length=211, Percent_Identity=31.7535545023697, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1790739, Length=233, Percent_Identity=29.6137339055794, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1790544, Length=217, Percent_Identity=31.7972350230415, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1788225, Length=227, Percent_Identity=30.8370044052863, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1786563, Length=203, Percent_Identity=33.0049261083744, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1786253, Length=204, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1786398, Length=170, Percent_Identity=32.9411764705882, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI87081791, Length=210, Percent_Identity=30, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1788165, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787029, Length=199, Percent_Identity=31.1557788944724, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI87081709, Length=228, Percent_Identity=28.5087719298246, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1790190, Length=238, Percent_Identity=25.6302521008403, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1789873, Length=210, Percent_Identity=32.3809523809524, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1788002, Length=235, Percent_Identity=32.3404255319149, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI87082268, Length=233, Percent_Identity=30.4721030042918, Blast_Score=71, Evalue=8e-14, Organism=Escherichia coli, GI1788472, Length=203, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786872, Length=221, Percent_Identity=31.6742081447964, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI48995001, Length=192, Percent_Identity=28.6458333333333, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1790467, Length=190, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1787758, Length=176, Percent_Identity=32.3863636363636, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1789032, Length=196, Percent_Identity=29.0816326530612, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1787041, Length=208, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788897, Length=215, Percent_Identity=26.5116279069767, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1788540, Length=200, Percent_Identity=29, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1789962, Length=227, Percent_Identity=26.431718061674, Blast_Score=65, Evalue=3e-12, Organism=Escherichia coli, GI1789991, Length=212, Percent_Identity=26.8867924528302, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1789593, Length=218, Percent_Identity=26.605504587156, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1790162, Length=215, Percent_Identity=30.2325581395349, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1787105, Length=184, Percent_Identity=33.695652173913, Blast_Score=65, Evalue=5e-12, Organism=Escherichia coli, GI1787712, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1788210, Length=200, Percent_Identity=26, Blast_Score=64, Evalue=9e-12, Organism=Escherichia coli, GI1788450, Length=220, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1788761, Length=203, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787370, Length=197, Percent_Identity=29.9492385786802, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI87082267, Length=212, Percent_Identity=28.3018867924528, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1789891, Length=188, Percent_Identity=31.9148936170213, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI48994943, Length=203, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI1786319, Length=200, Percent_Identity=27, Blast_Score=60, Evalue=9e-11, Organism=Escherichia coli, GI1787112, Length=235, Percent_Identity=27.6595744680851, Blast_Score=60, Evalue=1e-10, Organism=Caenorhabditis elegans, GI17565586, Length=178, Percent_Identity=33.1460674157303, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI115533608, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17541710, Length=187, Percent_Identity=32.0855614973262, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221500365, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007184, Length=214, Percent_Identity=28.9719626168224, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24581191, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24581189, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24581193, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24581195, Length=185, Percent_Identity=26.4864864864865, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI24581407, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI45552199, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 26918; Mature: 26918
Theoretical pI: Translated: 6.95; Mature: 6.95
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNSSLSLQALRYGHRQPLFAPLTLACRPGEIWAVLGANGRGKSTLLDTLTGVLPPLGGEM CCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCE QCEGGVALVPQSFRPAFRWRVSDVVLMGRARHVDLFAQPDEEDARRVEQALAQLGIAALA EECCCEEECCCCCCHHHHHHHHHHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHC EDDFGALSGGQQQLVLIARALVSASQNILLDEPCSALDLGNQQVVLQLIGDLAHRQARTV CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCHHHHHHHHHHHHHHCCCEE LFTTHDPNHALQVASHTLLLLPEGRWLAGETADVLSETHLRQAYGLPVRLIRHAASAFPL EEEECCCCHHHHCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCE LAPGFTLRR ECCCCCCCC >Mature Secondary Structure MNSSLSLQALRYGHRQPLFAPLTLACRPGEIWAVLGANGRGKSTLLDTLTGVLPPLGGEM CCCCCHHHHHHCCCCCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCE QCEGGVALVPQSFRPAFRWRVSDVVLMGRARHVDLFAQPDEEDARRVEQALAQLGIAALA EECCCEEECCCCCCHHHHHHHHHHEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHC EDDFGALSGGQQQLVLIARALVSASQNILLDEPCSALDLGNQQVVLQLIGDLAHRQARTV CCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCHHHHHHHHHHHHHHCCCEE LFTTHDPNHALQVASHTLLLLPEGRWLAGETADVLSETHLRQAYGLPVRLIRHAASAFPL EEEECCCCHHHHCCCCEEEEEECCCEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCE LAPGFTLRR ECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]
Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]