Click here to switch to the map view.

The map label for this gene is gltC [H]

Identifier: 238895161

GI number: 238895161

Start: 3042157

End: 3043050

Strand: Reverse

Name: gltC [H]

Synonym: KP1_3206

Alternate gene names: 238895161

Gene position: 3043050-3042157 (Counterclockwise)

Preceding gene: 238895164

Following gene: 238895160

Centisome position: 57.98

GC content: 66.33

Gene sequence:

>894_bases
ATGCGCATTGACGATATCGACGCTTTGCTGGCCACGGTGCAGTTTTCCTCCCTCAATCAGGCCGCGGAATATCTGGGGAT
CACCCAGTCGGCCATCACCCGGCGCCTGCAGCGTCTGGAACAGGAGCTGAACGTCACGCTGTTAGAGCGCCAGACCCGCC
CGCTGACCCTGACCGCCGCTGGACACCGGGTGTACGAGCAGTGTCTGAGCATTAAGCGTGAGACGAAAAAACTCTACAGC
CTGTTGGATCCGGAAGGCGAGCCGCGCGGCGCCCTGCGTCTCGGCGTGCCGCAGAGTCTCAGCGAGATTGCCCTGCCGGC
GGCGCTGTCGGCGCTGAGCCAGCAGTTTCCCGGACTGTCGCCGCAGATCACCTGCGGCTGGAGCGGACAGCTGCAGCGCC
GGCTGGAAAACGGCGAGCTGGACGGCATGCTGGCGATGGGGCCCGCCCAGCAAAGCTTCGCCGAGGGCTACAGCGGGCGC
CTGCTGTGTCCCCTGGAGGTGGTGCCGATCGTCGGCCGGCGTTTGAATTTGCGCGCGTCATCCCTGCGGGAGTGCGCCGA
ACGGGGCTGGATCCTTAACCCCGACGGCTGTGGCCTGCGCGCCGGGCTCATTCGCGAGCTGCAGAGCCAGGGATTGCGGT
TGACGCTCAACGTCGAGAGCGCGGGCGCGCAGCTGCAGATAGCGCTGGTGGCGCAGGGGCTGGGGCTGGGTCTGGTGCCG
AGGGCGGCGCTGGCCAGCAGCCCGTGGCGGGACGAGGTCGCGGTCCTAAGCCTCAGCGATTTTCAGCCTGCGGTCTCACT
GTGGCTGATCCACGCCCAGTATCTGGCGAACCTGCAGCCGCCGCTGACCTTTTTTGCCAGCAAAGTGGTTCAGCAGCTGA
CCGTATCCGACTGA

Upstream 100 bases:

>100_bases
TTCCTGTCAGAGGGACTGGTCAAAACGCTAACAGAGGCGTTAATATTATTTAAATGCAATTTACGCATATATTAATATGC
AAATTTCACATAAGGTTCCT

Downstream 100 bases:

>100_bases
AAGCACTATGCATTTTTGTTTAATGCTAATTAAGCATATTAAGATATGATAAAAATGCATTTTGCTCATTAACACGCTCT
GTATAGGGTAATGACCAGCG

Product: putative LysR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAAGHRVYEQCLSIKRETKKLYS
LLDPEGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLSPQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGR
LLCPLEVVPIVGRRLNLRASSLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVP
RAALASSPWRDEVAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD

Sequences:

>Translated_297_residues
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAAGHRVYEQCLSIKRETKKLYS
LLDPEGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLSPQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGR
LLCPLEVVPIVGRRLNLRASSLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVP
RAALASSPWRDEVAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD
>Mature_297_residues
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAAGHRVYEQCLSIKRETKKLYS
LLDPEGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLSPQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGR
LLCPLEVVPIVGRRLNLRASSLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVP
RAALASSPWRDEVAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=26.1648745519713, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787806, Length=287, Percent_Identity=25.7839721254355, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI145693105, Length=265, Percent_Identity=23.7735849056604, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=30.1587301587302, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=25, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32356; Mature: 32356

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCCCCEEEEEC
GHRVYEQCLSIKRETKKLYSLLDPEGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
PQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGRLLCPLEVVPIVGRRLNLRAS
CEEEECCCHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCEECHHHHHHHCCCCCCCCHH
SLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVP
HHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEECCCCCCCCC
RAALASSPWRDEVAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIDDIDALLATVQFSSLNQAAEYLGITQSAITRRLQRLEQELNVTLLERQTRPLTLTAA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCEEEEECCCCCEEEEEC
GHRVYEQCLSIKRETKKLYSLLDPEGEPRGALRLGVPQSLSEIALPAALSALSQQFPGLS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
PQITCGWSGQLQRRLENGELDGMLAMGPAQQSFAEGYSGRLLCPLEVVPIVGRRLNLRAS
CEEEECCCHHHHHHHCCCCCCCEEEECCCHHHHHCCCCCCEECHHHHHHHCCCCCCCCHH
SLRECAERGWILNPDGCGLRAGLIRELQSQGLRLTLNVESAGAQLQIALVAQGLGLGLVP
HHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEEECCCCCCCCC
RAALASSPWRDEVAVLSLSDFQPAVSLWLIHAQYLANLQPPLTFFASKVVQQLTVSD
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]