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The map label for this gene is hipO [H]

Identifier: 238895139

GI number: 238895139

Start: 3019637

End: 3020794

Strand: Reverse

Name: hipO [H]

Synonym: KP1_3179

Alternate gene names: 238895139

Gene position: 3020794-3019637 (Counterclockwise)

Preceding gene: 238895144

Following gene: 238895136

Centisome position: 57.56

GC content: 66.15

Gene sequence:

>1158_bases
ATGGCCGTATCGCCGTCACTGATCGCCGAAGCCGTTGGCTGGCGACGTGAATTTCACGCCGCGCCTGAGCTCGGATATCA
GGAACAGGAGACCTCGCGCCGCGTTGCGGAGCTGCTGGCCTCGTTTGGGCTGCAGGTGCACCGCGGGCTGGCTGGCACCG
GCGTCGTGGCGACGCTGGAGAACGGCCCCGGGCCGGTTATCGGCCTGCGCGCCGATATGGACGCCCTGCCGATCACTGAG
CTGGGGAGCGTCAGCTACCGTTCACGCCGTCCCGGGGTGATGCACGCCTGCGGCCACGATGGCCATACCGCGATGCTGCT
GGCGGCCGCCTCCCATCTGGCGCAGACCCGCCATTTCAGCGGCACCGTCCACTTTGTCTTTCAGCCGGCGGAAGAGAACC
TCGGCGGCGCGCGCAAAATGGTGGAGGAGGGGTTGTTTGAGCGCTTCCCGATGGACGCCATCTACGCGCTGCATAACTGG
CCGGGGATCCCTCTTGGCGAAGTGGCGCTCAGCGATGGCGCGATGATGGCCTCGCTGGACGCCTTCGAGATCACCCTGCG
CGGAAAGAGCTGTCATGCGGCGATGCCGGAGAGCGGGGCCGATCCGATCGTCGCGGCGGCGCAGCTGATAATGGCGCTGC
AGACCATTCCTTCCCGCCGCTTGTCGCCGCAGGATTCCGCGGTGGTCAGCATCACCCAGATAAACGGCGGCGAGGCGATC
AACGTCCTGCCAGACACCGTGGTGCTGCGCGGTACCTTCCGCTGCCTGAGCAATCGCGTTCGCGCCCGCGTGCGGGAGCT
CATCGAAAGCTATGTGGCGACCCAGCCGCAGGTGTCCGATGTGCAGGGCGAGATTAGCTGGTTCCCGGGTTATCCGGTGA
CCAAAAACCATGCGCTGCAGGCGCAGCAGGTGCGCGAGGTGGCTGCCGCCACTCTCGGCGCGCAAGCGGTGCGCTGGAAT
CAGGCGCCGTCGATGGCCTCCGAAGATTTTGCCTGCATGCTGGAGGCCTGTCCGGGGGCCTATTTCTGGATAGGCACCGA
CGGCGAAACCCCGTCGAAGCCGCTGCATAACGCCAGCTATGACTTTAACGATGCGCTGATCGGCCCCGGCGTCGCCATGT
GGGTGGGGCTGGTGGAGAAACAGCTGCCGGCGGCGTAA

Upstream 100 bases:

>100_bases
ACGGAGGGAGCGGCAGCGCCCCGACGCCGGTGAGCGACGGGGAAAAACGCGACGCATGACCGATTATTCAGCATTACGCT
ATGCAGGAAAGGAGTAATAC

Downstream 100 bases:

>100_bases
CCCACCGGCAGCGGCAGAGGGAGCGCGCTGCGCTCCCTGAGGTCAGACGTCGGCAGCGGCTTTCAGTCGCGCTTTCATGT
CGCTGTAGGCCGTCCAGGCA

Product: putative metal-dependent amidase/aminoacylase/carboxypeptidase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAVSPSLIAEAVGWRREFHAAPELGYQEQETSRRVAELLASFGLQVHRGLAGTGVVATLENGPGPVIGLRADMDALPITE
LGSVSYRSRRPGVMHACGHDGHTAMLLAAASHLAQTRHFSGTVHFVFQPAEENLGGARKMVEEGLFERFPMDAIYALHNW
PGIPLGEVALSDGAMMASLDAFEITLRGKSCHAAMPESGADPIVAAAQLIMALQTIPSRRLSPQDSAVVSITQINGGEAI
NVLPDTVVLRGTFRCLSNRVRARVRELIESYVATQPQVSDVQGEISWFPGYPVTKNHALQAQQVREVAAATLGAQAVRWN
QAPSMASEDFACMLEACPGAYFWIGTDGETPSKPLHNASYDFNDALIGPGVAMWVGLVEKQLPAA

Sequences:

>Translated_385_residues
MAVSPSLIAEAVGWRREFHAAPELGYQEQETSRRVAELLASFGLQVHRGLAGTGVVATLENGPGPVIGLRADMDALPITE
LGSVSYRSRRPGVMHACGHDGHTAMLLAAASHLAQTRHFSGTVHFVFQPAEENLGGARKMVEEGLFERFPMDAIYALHNW
PGIPLGEVALSDGAMMASLDAFEITLRGKSCHAAMPESGADPIVAAAQLIMALQTIPSRRLSPQDSAVVSITQINGGEAI
NVLPDTVVLRGTFRCLSNRVRARVRELIESYVATQPQVSDVQGEISWFPGYPVTKNHALQAQQVREVAAATLGAQAVRWN
QAPSMASEDFACMLEACPGAYFWIGTDGETPSKPLHNASYDFNDALIGPGVAMWVGLVEKQLPAA
>Mature_384_residues
AVSPSLIAEAVGWRREFHAAPELGYQEQETSRRVAELLASFGLQVHRGLAGTGVVATLENGPGPVIGLRADMDALPITEL
GSVSYRSRRPGVMHACGHDGHTAMLLAAASHLAQTRHFSGTVHFVFQPAEENLGGARKMVEEGLFERFPMDAIYALHNWP
GIPLGEVALSDGAMMASLDAFEITLRGKSCHAAMPESGADPIVAAAQLIMALQTIPSRRLSPQDSAVVSITQINGGEAIN
VLPDTVVLRGTFRCLSNRVRARVRELIESYVATQPQVSDVQGEISWFPGYPVTKNHALQAQQVREVAAATLGAQAVRWNQ
APSMASEDFACMLEACPGAYFWIGTDGETPSKPLHNASYDFNDALIGPGVAMWVGLVEKQLPAA

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=413, Percent_Identity=28.8135593220339, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41242; Mature: 41111

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSPSLIAEAVGWRREFHAAPELGYQEQETSRRVAELLASFGLQVHRGLAGTGVVATLE
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCEEEEEE
NGPGPVIGLRADMDALPITELGSVSYRSRRPGVMHACGHDGHTAMLLAAASHLAQTRHFS
CCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
GTVHFVFQPAEENLGGARKMVEEGLFERFPMDAIYALHNWPGIPLGEVALSDGAMMASLD
CEEEEEEECCHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCEEEECC
AFEITLRGKSCHAAMPESGADPIVAAAQLIMALQTIPSRRLSPQDSAVVSITQINGGEAI
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEE
NVLPDTVVLRGTFRCLSNRVRARVRELIESYVATQPQVSDVQGEISWFPGYPVTKNHALQ
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEECCCCCCCCCCCHH
AQQVREVAAATLGAQAVRWNQAPSMASEDFACMLEACPGAYFWIGTDGETPSKPLHNASY
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
DFNDALIGPGVAMWVGLVEKQLPAA
CCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVSPSLIAEAVGWRREFHAAPELGYQEQETSRRVAELLASFGLQVHRGLAGTGVVATLE
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCCEEEEEE
NGPGPVIGLRADMDALPITELGSVSYRSRRPGVMHACGHDGHTAMLLAAASHLAQTRHFS
CCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCC
GTVHFVFQPAEENLGGARKMVEEGLFERFPMDAIYALHNWPGIPLGEVALSDGAMMASLD
CEEEEEEECCHHCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHCCCCEEEECC
AFEITLRGKSCHAAMPESGADPIVAAAQLIMALQTIPSRRLSPQDSAVVSITQINGGEAI
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCEE
NVLPDTVVLRGTFRCLSNRVRARVRELIESYVATQPQVSDVQGEISWFPGYPVTKNHALQ
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEECCCCCCCCCCCHH
AQQVREVAAATLGAQAVRWNQAPSMASEDFACMLEACPGAYFWIGTDGETPSKPLHNASY
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
DFNDALIGPGVAMWVGLVEKQLPAA
CCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]