BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is hbdH1 [H]

Identifier: 238895098

GI number: 238895098

Start: 2976160

End: 2976930

Strand: Direct

Name: hbdH1 [H]

Synonym: KP1_3134

Alternate gene names: 238895098

Gene position: 2976160-2976930 (Clockwise)

Preceding gene: 238895097

Following gene: 238895100

Centisome position: 56.7

GC content: 64.98

Gene sequence:

>771_bases
ATGAACTTACACGGTAAAACGGCGCTGGTCACCGGCTCCACCAGCGGCATCGGTTTAGGGATCGCCAAAGTGCTGGCGCA
GGCAGGCGCCCAGCTGGTGCTCAATGGCTTCGGCGACAGCAGCCACGCCCGGGCTGAAGTCGCCGCGCTGGGCAAGATCC
CCGGCTATCACGACGCCGACCTGCGCGACGTCGGGCAGATCGAGGCGATGATGCACTATGCCGAAAGCACCTTCGGCGGC
GTCGATATCGTGATCAATAACGCCGGCATCCAGCACGTGGCCCCGGTGGAGCAGTTCCCGGTGGACAAATGGAACGATAT
TCTCGCCATCAATCTCTCCAGCGTCTTCCACACCACCCGCCTGGCGCTGCCGGGTATGCGCCAGCGCAACTGGGGGCGCA
TCATCAACATTGCCTCAGTGCATGGCCTGGTGGCGTCGAAAGAGAAATCGGCCTACGTCGCCGCCAAGCACGCGGTGGTC
GGGCTGACCAAAACCGTGGCCCTGGAAACCGCGCGTAGCGGCATCACCTGCAACGCCATCTGCCCTGGCTGGGTGCTAAC
CCCGCTGGTGCAGCAGCAGATCGACAAACGCATCGCCGAGGGGGTCGACCCGGAGCAGGCCAGCGCCCAGCTGCTGGCGG
AAAAGCAGCCCTCCGGGGAGTTTGTCACCCCGCAGCAGCTGGGCGAAATGGCACTGTTTCTGTGCAGCGACGCCGCCGCC
CAGGTGCGCGGCGCCGCATGGAACATGGATGGCGGCTGGGTGGCGCAGTAA

Upstream 100 bases:

>100_bases
TTTTCGCCATCACGGTGATCAAAAGCCTCGCGGTACTGTTTGTCATTGCCACGTTCTATGTGACCGGCATTGTCTGATAC
CAGATTGAAGGAGTAATAAA

Downstream 100 bases:

>100_bases
GCCGCTGGCGCCGCGAAGATCAGAACATCGCCAGAAAGCGTTTCACCGTACGCGAGCGCTCGAAGCGCCGCCAGGCGATG
GCGATATCGGTCTTCAGCGG

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNLHGKTALVTGSTSGIGLGIAKVLAQAGAQLVLNGFGDSSHARAEVAALGKIPGYHDADLRDVGQIEAMMHYAESTFGG
VDIVINNAGIQHVAPVEQFPVDKWNDILAINLSSVFHTTRLALPGMRQRNWGRIINIASVHGLVASKEKSAYVAAKHAVV
GLTKTVALETARSGITCNAICPGWVLTPLVQQQIDKRIAEGVDPEQASAQLLAEKQPSGEFVTPQQLGEMALFLCSDAAA
QVRGAAWNMDGGWVAQ

Sequences:

>Translated_256_residues
MNLHGKTALVTGSTSGIGLGIAKVLAQAGAQLVLNGFGDSSHARAEVAALGKIPGYHDADLRDVGQIEAMMHYAESTFGG
VDIVINNAGIQHVAPVEQFPVDKWNDILAINLSSVFHTTRLALPGMRQRNWGRIINIASVHGLVASKEKSAYVAAKHAVV
GLTKTVALETARSGITCNAICPGWVLTPLVQQQIDKRIAEGVDPEQASAQLLAEKQPSGEFVTPQQLGEMALFLCSDAAA
QVRGAAWNMDGGWVAQ
>Mature_256_residues
MNLHGKTALVTGSTSGIGLGIAKVLAQAGAQLVLNGFGDSSHARAEVAALGKIPGYHDADLRDVGQIEAMMHYAESTFGG
VDIVINNAGIQHVAPVEQFPVDKWNDILAINLSSVFHTTRLALPGMRQRNWGRIINIASVHGLVASKEKSAYVAAKHAVV
GLTKTVALETARSGITCNAICPGWVLTPLVQQQIDKRIAEGVDPEQASAQLLAEKQPSGEFVTPQQLGEMALFLCSDAAA
QVRGAAWNMDGGWVAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=31.496062992126, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=28.3018867924528, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4504505, Length=264, Percent_Identity=28.030303030303, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI31542939, Length=224, Percent_Identity=31.6964285714286, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=26.8199233716475, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI32483357, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI20149619, Length=232, Percent_Identity=30.6034482758621, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI109715829, Length=246, Percent_Identity=31.3008130081301, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI59889578, Length=220, Percent_Identity=30.4545454545455, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=29.2490118577075, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=31.6091954022989, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=207, Percent_Identity=29.951690821256, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=25.0996015936255, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7657478, Length=207, Percent_Identity=29.4685990338164, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI142976729, Length=215, Percent_Identity=27.4418604651163, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=255, Percent_Identity=27.0588235294118, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=29.3650793650794, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=31.9796954314721, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI157739938, Length=190, Percent_Identity=25.2631578947368, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI83715985, Length=186, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI210032110, Length=189, Percent_Identity=29.1005291005291, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI223718074, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI40254986, Length=191, Percent_Identity=27.2251308900524, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=37.2549019607843, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=34.6456692913386, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=35.6589147286822, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=31.5589353612167, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=30.7392996108949, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.8300395256917, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=29.4573643410853, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1789057, Length=183, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=26.5625, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.5275590551181, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=28.6516853932584, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789378, Length=256, Percent_Identity=25, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI2367365, Length=250, Percent_Identity=26.8, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=29.296875, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=30.859375, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=27.843137254902, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=28.0155642023346, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=260, Percent_Identity=30.3846153846154, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=30.8900523560209, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=190, Percent_Identity=31.0526315789474, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17568967, Length=267, Percent_Identity=26.2172284644195, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.6875, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17538182, Length=205, Percent_Identity=32.6829268292683, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=264, Percent_Identity=27.6515151515151, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=28.4974093264249, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=271, Percent_Identity=29.520295202952, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=28.7878787878788, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=265, Percent_Identity=28.6792452830189, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=27.037037037037, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=28.7878787878788, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=25.9541984732824, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=26.2626262626263, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=27.4725274725275, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=198, Percent_Identity=28.7878787878788, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=25.78125, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=197, Percent_Identity=30.9644670050761, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=25.4826254826255, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.9245283018868, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=26.2172284644195, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=258, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=195, Percent_Identity=25.1282051282051, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=195, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=265, Percent_Identity=27.5471698113208, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320089, Length=220, Percent_Identity=26.3636363636364, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI18859837, Length=264, Percent_Identity=28.7878787878788, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=29.3436293436293, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=29.2490118577075, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=32.0158102766798, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=29.9212598425197, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21358495, Length=226, Percent_Identity=28.3185840707965, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=27.843137254902, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28571387, Length=209, Percent_Identity=29.1866028708134, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24665243, Length=205, Percent_Identity=30.7317073170732, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221331218, Length=205, Percent_Identity=30.7317073170732, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24665247, Length=206, Percent_Identity=30.5825242718447, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221331216, Length=206, Percent_Identity=30.5825242718447, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355631, Length=172, Percent_Identity=30.2325581395349, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=29.0598290598291, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=27.6679841897233, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=33.6734693877551, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=205, Percent_Identity=30.7317073170732, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=29.8969072164948, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=29.8969072164948, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=29.6875, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=29.6875, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281364892, Length=237, Percent_Identity=26.5822784810127, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644337, Length=258, Percent_Identity=29.0697674418605, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356301, Length=226, Percent_Identity=24.7787610619469, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007238, Length=177, Percent_Identity=31.0734463276836, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27009; Mature: 27009

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHGKTALVTGSTSGIGLGIAKVLAQAGAQLVLNGFGDSSHARAEVAALGKIPGYHDAD
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCC
LRDVGQIEAMMHYAESTFGGVDIVINNAGIQHVAPVEQFPVDKWNDILAINLSSVFHTTR
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHH
LALPGMRQRNWGRIINIASVHGLVASKEKSAYVAAKHAVVGLTKTVALETARSGITCNAI
HHCCCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
CPGWVLTPLVQQQIDKRIAEGVDPEQASAQLLAEKQPSGEFVTPQQLGEMALFLCSDAAA
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCHHH
QVRGAAWNMDGGWVAQ
HHCCCEECCCCCEECC
>Mature Secondary Structure
MNLHGKTALVTGSTSGIGLGIAKVLAQAGAQLVLNGFGDSSHARAEVAALGKIPGYHDAD
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCC
LRDVGQIEAMMHYAESTFGGVDIVINNAGIQHVAPVEQFPVDKWNDILAINLSSVFHTTR
HHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEEEEHHHHHHHHH
LALPGMRQRNWGRIINIASVHGLVASKEKSAYVAAKHAVVGLTKTVALETARSGITCNAI
HHCCCCCCCCCCCEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
CPGWVLTPLVQQQIDKRIAEGVDPEQASAQLLAEKQPSGEFVTPQQLGEMALFLCSDAAA
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCHHH
QVRGAAWNMDGGWVAQ
HHCCCEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA