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The map label for this gene is lpsI [H]

Identifier: 238895093

GI number: 238895093

Start: 2971206

End: 2971913

Strand: Direct

Name: lpsI [H]

Synonym: KP1_3129

Alternate gene names: 238895093

Gene position: 2971206-2971913 (Clockwise)

Preceding gene: 238895091

Following gene: 238895094

Centisome position: 56.61

GC content: 64.12

Gene sequence:

>708_bases
ATGGCAGGACTGGATAAACGCGTCGCCAGTTACGAAGCGGCGCTGGAAGGGTTAACGGACGGCATGACGCTGCTCGCCGG
CGGCTTCGGCCTGTGCGGCATTCCCGAGAACTTGATCGCCGAGGTGCAGCGTCGCCAGGTGCAGGGGCTGACGGTGGTCT
CCAACAACTGCGGGGTCGACGGTTTCGGTCTCGGCATGCTGCTGGAGTCGCGCCAGGTCAGCAAGGTGGTGGCCTCTTAC
GTCGGGGAAAACGCGCTGTTTGAACAGCTGGTGCTGAGCGGCGAGCTGGCGGTAGAACTCACCCCGCAGGGAACGCTGGC
GGAAAAAATCCGCGCCGGCGGCGCCGGCATCCCCGGCTTTTACACCGCCACCGGGTATGGCACCCCGGTCGCCGAAGGCA
AAGAGGTGCGCCAGTTCGACGGCCGACACTACATCCTTGAAGAGGCGATCCGCGGCGATTTCGCGCTGGTCAAAGGCTGG
AAAGCCGACTGGTACGGCAACGTGGTCTATCGCCACACCGCGCAGAATTTCAACCCGCTGATGGCCACCGCCGGGCGCAT
TACGGTGGTGGAGGTGGAAGAGATTGTGCCGCCGGGCGAACTGCCCCCCTCCGCCATCCATACTCCGGGGATCTATGTCG
ACCGGCTGATCGTCGGGCAATTCGAAAAACGTATTGAACAGCGCACCCTGCGCGCCGGAGGGCACTGA

Upstream 100 bases:

>100_bases
GAAATTAATTAAAATTCCAAATGAGTGGGTCACAAATTCAAAATTATCAAATCAGTCGCCTGCGCCAATGATAAGGCTAT
CGCAAGGCAGGAGAGACAAG

Downstream 100 bases:

>100_bases
GATGCTGACCCGTGAACAAATGGCGATGCGCGTCGCCCAGGAGCTGCGCGACGGCGACTACGTCAACCTCGGGATCGGTA
TCCCGACGCTGGTGGCCAAC

Product: putative acetyl-CoA:acetoacetyl-CoA transferase alpha subunit

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MAGLDKRVASYEAALEGLTDGMTLLAGGFGLCGIPENLIAEVQRRQVQGLTVVSNNCGVDGFGLGMLLESRQVSKVVASY
VGENALFEQLVLSGELAVELTPQGTLAEKIRAGGAGIPGFYTATGYGTPVAEGKEVRQFDGRHYILEEAIRGDFALVKGW
KADWYGNVVYRHTAQNFNPLMATAGRITVVEVEEIVPPGELPPSAIHTPGIYVDRLIVGQFEKRIEQRTLRAGGH

Sequences:

>Translated_235_residues
MAGLDKRVASYEAALEGLTDGMTLLAGGFGLCGIPENLIAEVQRRQVQGLTVVSNNCGVDGFGLGMLLESRQVSKVVASY
VGENALFEQLVLSGELAVELTPQGTLAEKIRAGGAGIPGFYTATGYGTPVAEGKEVRQFDGRHYILEEAIRGDFALVKGW
KADWYGNVVYRHTAQNFNPLMATAGRITVVEVEEIVPPGELPPSAIHTPGIYVDRLIVGQFEKRIEQRTLRAGGH
>Mature_234_residues
AGLDKRVASYEAALEGLTDGMTLLAGGFGLCGIPENLIAEVQRRQVQGLTVVSNNCGVDGFGLGMLLESRQVSKVVASYV
GENALFEQLVLSGELAVELTPQGTLAEKIRAGGAGIPGFYTATGYGTPVAEGKEVRQFDGRHYILEEAIRGDFALVKGWK
ADWYGNVVYRHTAQNFNPLMATAGRITVVEVEEIVPPGELPPSAIHTPGIYVDRLIVGQFEKRIEQRTLRAGGH

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=240, Percent_Identity=59.5833333333333, Blast_Score=276, Evalue=9e-75,
Organism=Homo sapiens, GI11545841, Length=235, Percent_Identity=58.7234042553191, Blast_Score=257, Evalue=8e-69,
Organism=Escherichia coli, GI1788551, Length=220, Percent_Identity=41.8181818181818, Blast_Score=177, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17531517, Length=247, Percent_Identity=51.417004048583, Blast_Score=256, Evalue=7e-69,
Organism=Drosophila melanogaster, GI21358325, Length=239, Percent_Identity=52.3012552301255, Blast_Score=241, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24655794, Length=239, Percent_Identity=52.3012552301255, Blast_Score=240, Evalue=6e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25230; Mature: 25099

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLDKRVASYEAALEGLTDGMTLLAGGFGLCGIPENLIAEVQRRQVQGLTVVSNNCGVD
CCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCC
GFGLGMLLESRQVSKVVASYVGENALFEQLVLSGELAVELTPQGTLAEKIRAGGAGIPGF
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCC
YTATGYGTPVAEGKEVRQFDGRHYILEEAIRGDFALVKGWKADWYGNVVYRHTAQNFNPL
EEECCCCCCCCCCHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCCCCCHH
MATAGRITVVEVEEIVPPGELPPSAIHTPGIYVDRLIVGQFEKRIEQRTLRAGGH
HHCCCCEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGLDKRVASYEAALEGLTDGMTLLAGGFGLCGIPENLIAEVQRRQVQGLTVVSNNCGVD
CCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCC
GFGLGMLLESRQVSKVVASYVGENALFEQLVLSGELAVELTPQGTLAEKIRAGGAGIPGF
CHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCC
YTATGYGTPVAEGKEVRQFDGRHYILEEAIRGDFALVKGWKADWYGNVVYRHTAQNFNPL
EEECCCCCCCCCCHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCEEEEECCCCCCHH
MATAGRITVVEVEEIVPPGELPPSAIHTPGIYVDRLIVGQFEKRIEQRTLRAGGH
HHCCCCEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]