BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is yusZ [H]

Identifier: 238895049

GI number: 238895049

Start: 2934774

End: 2935526

Strand: Reverse

Name: yusZ [H]

Synonym: KP1_3081

Alternate gene names: 238895049

Gene position: 2935526-2934774 (Counterclockwise)

Preceding gene: 238895051

Following gene: 238895048

Centisome position: 55.93

GC content: 62.95

Gene sequence:

>753_bases
ATGCAAACGATAATGATCACCGGCTGTTCATCGGGTTTTGGCCTGGAGACGGCGCGTTATTTTCTCGAGCAAGGCTGGAA
GGTTATTGCCACGATGCGCGCTCCGCAGGAAGGTGTGTTACCCGCCAGCGACCGCCTGCGGCTGGTACGTCTTGACGTCA
CTTCGGCGCAGAGTATCGCAGAGGCCATTGCCGAAGTCGGAGAGATTGATGTGCTGGTTAACAACGCCGGGGTGGGGATG
CTTAATGCCCTGGAGGGCGCCCCGCGCGAGGCGATAGCCAACCTGTTTGCCACCAATACCCTGGGAACGATTGCCATGAC
CCAGGCGGTGATCCCCCGGTTCAGAGAGCGCCGAAGCGGGACCATCGTTAATATTACCTCGGCGGTCACCCTGCAACCGA
TGCCCCTGCTGGCTGTCTACACCGCGAGTAAGGCGGCGGTGAATGCCTTCACGGAGTCGCTGGCGCTGGAGCTCCGTGCT
TTTAATATTCGCGTCGGGCTGATCCTCCCGGGACGCGCCCCGCAGACCCGGTTCGGGGAAAACGCCCGCCGGACGATGGG
GCAGCTCCCGGAGAGCTATGCGGCGCTCGGCCAGCAGATCTTCGACAGCATGCAGGATAACGCCAGCGTGACGCAGGCGA
CCGATGTCGCTCAGGCCGTCTGGCGAATGGTGCACGATCCTGATGCCCCTTCGCGGCTGCCGGCAGGGGAAGACGCCCTG
GCGATGGCGCAGGCCAGTCATCGCCTTGCCTGA

Upstream 100 bases:

>100_bases
ATTTCCGGACTCCTGCTAAAGAATGATGGATTATTGACCCTATATCGTCCGGCACGGCCTGTCTATGATCAAAAGGAAGA
AGCCATTCGGAGACAGAGAT

Downstream 100 bases:

>100_bases
AGGCAATATGCGGGACTTGTCTGTCAGACGGTGGGTGCGCAAGCTGCCCTGCGCTTTATGGTCGGGGAATATTATCTCTG
TCAGGATCGCCTGGATAATA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MQTIMITGCSSGFGLETARYFLEQGWKVIATMRAPQEGVLPASDRLRLVRLDVTSAQSIAEAIAEVGEIDVLVNNAGVGM
LNALEGAPREAIANLFATNTLGTIAMTQAVIPRFRERRSGTIVNITSAVTLQPMPLLAVYTASKAAVNAFTESLALELRA
FNIRVGLILPGRAPQTRFGENARRTMGQLPESYAALGQQIFDSMQDNASVTQATDVAQAVWRMVHDPDAPSRLPAGEDAL
AMAQASHRLA

Sequences:

>Translated_250_residues
MQTIMITGCSSGFGLETARYFLEQGWKVIATMRAPQEGVLPASDRLRLVRLDVTSAQSIAEAIAEVGEIDVLVNNAGVGM
LNALEGAPREAIANLFATNTLGTIAMTQAVIPRFRERRSGTIVNITSAVTLQPMPLLAVYTASKAAVNAFTESLALELRA
FNIRVGLILPGRAPQTRFGENARRTMGQLPESYAALGQQIFDSMQDNASVTQATDVAQAVWRMVHDPDAPSRLPAGEDAL
AMAQASHRLA
>Mature_250_residues
MQTIMITGCSSGFGLETARYFLEQGWKVIATMRAPQEGVLPASDRLRLVRLDVTSAQSIAEAIAEVGEIDVLVNNAGVGM
LNALEGAPREAIANLFATNTLGTIAMTQAVIPRFRERRSGTIVNITSAVTLQPMPLLAVYTASKAAVNAFTESLALELRA
FNIRVGLILPGRAPQTRFGENARRTMGQLPESYAALGQQIFDSMQDNASVTQATDVAQAVWRMVHDPDAPSRLPAGEDAL
AMAQASHRLA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=254, Percent_Identity=35.0393700787402, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI223718074, Length=182, Percent_Identity=37.9120879120879, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI20149619, Length=184, Percent_Identity=33.695652173913, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19743808, Length=266, Percent_Identity=30.0751879699248, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI119392083, Length=199, Percent_Identity=32.1608040201005, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI150247226, Length=180, Percent_Identity=35, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI44680136, Length=226, Percent_Identity=27.8761061946903, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI44680133, Length=226, Percent_Identity=27.8761061946903, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI17738292, Length=226, Percent_Identity=27.8761061946903, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40548397, Length=181, Percent_Identity=35.3591160220994, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI214010158, Length=181, Percent_Identity=35.3591160220994, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI214010156, Length=181, Percent_Identity=35.3591160220994, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI22758144, Length=181, Percent_Identity=35.3591160220994, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI22507405, Length=222, Percent_Identity=30.6306306306306, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI50726952, Length=246, Percent_Identity=31.3008130081301, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=31.7948717948718, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI4504503, Length=182, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4557649, Length=184, Percent_Identity=30.9782608695652, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705855, Length=180, Percent_Identity=29.4444444444444, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI7705925, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=26.0204081632653, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=179, Percent_Identity=28.4916201117318, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=179, Percent_Identity=28.4916201117318, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI10190704, Length=199, Percent_Identity=31.1557788944724, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI210032110, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI157739938, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=33.920704845815, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=34.020618556701, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1786812, Length=174, Percent_Identity=30.4597701149425, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=32.0855614973262, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787335, Length=175, Percent_Identity=34.2857142857143, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790717, Length=185, Percent_Identity=29.1891891891892, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082100, Length=202, Percent_Identity=32.1782178217822, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=190, Percent_Identity=32.1052631578947, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=232, Percent_Identity=29.7413793103448, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=223, Percent_Identity=31.8385650224215, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=210, Percent_Identity=30.952380952381, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559964, Length=211, Percent_Identity=30.8056872037915, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=202, Percent_Identity=29.7029702970297, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532177, Length=226, Percent_Identity=27.4336283185841, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=185, Percent_Identity=31.3513513513514, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17559962, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=186, Percent_Identity=30.6451612903226, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=186, Percent_Identity=29.5698924731183, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=209, Percent_Identity=29.1866028708134, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=211, Percent_Identity=30.3317535545024, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=185, Percent_Identity=30.8108108108108, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=222, Percent_Identity=29.2792792792793, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=264, Percent_Identity=26.1363636363636, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=240, Percent_Identity=28.75, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=191, Percent_Identity=31.9371727748691, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=191, Percent_Identity=31.9371727748691, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=191, Percent_Identity=37.696335078534, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322067, Length=247, Percent_Identity=25.9109311740891, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24651139, Length=194, Percent_Identity=29.8969072164948, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24643142, Length=172, Percent_Identity=32.5581395348837, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=184, Percent_Identity=31.5217391304348, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI23397609, Length=230, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24639444, Length=178, Percent_Identity=35.9550561797753, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24584744, Length=183, Percent_Identity=30.6010928961749, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28574402, Length=183, Percent_Identity=30.6010928961749, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24584748, Length=210, Percent_Identity=25.2380952380952, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076933, Length=210, Percent_Identity=25.2380952380952, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=182, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=181, Percent_Identity=32.5966850828729, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640442, Length=183, Percent_Identity=27.3224043715847, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007236, Length=192, Percent_Identity=29.6875, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24644339, Length=181, Percent_Identity=30.3867403314917, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007238, Length=184, Percent_Identity=29.3478260869565, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922066, Length=223, Percent_Identity=27.3542600896861, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584752, Length=220, Percent_Identity=26.3636363636364, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571387, Length=243, Percent_Identity=30.4526748971193, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=27.5449101796407, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26780; Mature: 26780

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIMITGCSSGFGLETARYFLEQGWKVIATMRAPQEGVLPASDRLRLVRLDVTSAQSIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHHH
EAIAEVGEIDVLVNNAGVGMLNALEGAPREAIANLFATNTLGTIAMTQAVIPRFRERRSG
HHHHHCCCEEEEEECCCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
TIVNITSAVTLQPMPLLAVYTASKAAVNAFTESLALELRAFNIRVGLILPGRAPQTRFGE
CEEEEECEEEECCCCEEEEEHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCCCCCC
NARRTMGQLPESYAALGQQIFDSMQDNASVTQATDVAQAVWRMVHDPDAPSRLPAGEDAL
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
AMAQASHRLA
HHHHHHHCCC
>Mature Secondary Structure
MQTIMITGCSSGFGLETARYFLEQGWKVIATMRAPQEGVLPASDRLRLVRLDVTSAQSIA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCHHHHH
EAIAEVGEIDVLVNNAGVGMLNALEGAPREAIANLFATNTLGTIAMTQAVIPRFRERRSG
HHHHHCCCEEEEEECCCCCHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
TIVNITSAVTLQPMPLLAVYTASKAAVNAFTESLALELRAFNIRVGLILPGRAPQTRFGE
CEEEEECEEEECCCCEEEEEHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCCCCCCCCCC
NARRTMGQLPESYAALGQQIFDSMQDNASVTQATDVAQAVWRMVHDPDAPSRLPAGEDAL
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
AMAQASHRLA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]