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The map label for this gene is tehA [H]

Identifier: 238894982

GI number: 238894982

Start: 2869154

End: 2870158

Strand: Reverse

Name: tehA [H]

Synonym: KP1_3008

Alternate gene names: 238894982

Gene position: 2870158-2869154 (Counterclockwise)

Preceding gene: 238894984

Following gene: 238894981

Centisome position: 54.69

GC content: 62.19

Gene sequence:

>1005_bases
ATGAATAAAACACAAACGCCGCGGCAGGTGCTAAACCTGCCGGCGGGTTATTTTGGCATGGTGCTCGGCACCATCGGAAT
GGGCTTCGCCTGGCGTTACGCCAGCACCCTCTGGCCGGTCAGCCGCAGCATTGGTGATGGGCTGGTGACGCTGGCGATGG
CGATGTGGGTCCTGCTCAGTATGGCGTTTATCAGCCGGGCGATCCGCTTTCCGGCGAGCGTGCTGCGGGAGATGCGTCAT
CCGGTCAGCAGCAGCTTCGTCAGCCTGTTTCCGGCCACCACGCTGTTGGTGGCGATTGGTTTGGCTCCCTGGTGCCGGCC
GCTGGCGATCGGGCTGTTTGTGCCGGGCGTGGCGCTGCAGCTCGCCTATGCCGCCTGGCAAAGCGGTGGGCTATGGCGGG
GGAACCATCCTCGCGAGGCCACCACGCCGGGGTTGTATCTGCCGACAGTAGCCAATAATTTTATCAGCGCGATGGCCTGC
GGCGCGCTGGGATTTTCCGATGCCGGACTGGTGTTCCTCGGCGCCGGGGTCTTCTCCTGGCTGAGCCTCGAGCCGGCGAT
CCTCCAGCGTCTGCGCAGCGCAGGCGAGCTGCCGACGCCGCTGCGCACCTCGCTGGGGATCCAGCTGGCGCCTGCGCTGG
TGGCCTGCAGCGCCTGGCTCAGCGTCAACGGCGGGGAGGCCGATACCTTCGCTAAGCTGCTGTTTGGTTACGGCCTGCTG
CAGCTACTGTTTATGCTCCGTCTGATGCCCTGGTATCTTCGTCAGCCGTTCAATGCTTCTTTCTGGAGCTTCTCGTTCGG
CATTTCCGCGCTGGCCACCACCGGTCTGCATCTCGGCCAGGCCAGGGGAGACGGCTTTTTTCATCATCTGGCGATGCCGC
TATTTATTTTTAGCAATCTGGTTGTCGGCCTGCTGCTGCTGCGTACAGCGTTGCTGTTGGTTAGCGGGAAACTGTTGCTC
CAAGTCGACCGGGAAACACTCCTGAATAAGAAGGAAGGATCATGA

Upstream 100 bases:

>100_bases
ATTACTTATGGTTAACATAAACATAGCAAAGATCGCCATAGCGCGCGGGATAAGGTTCCTTTAGAATGCAACTTCAAATT
AAATTGATATCATCAGTAAA

Downstream 100 bases:

>100_bases
CAAAGCGTGACGCGGATTATTTTAGTCAAAAATACAGCCTGACCCGCACCCATTCCGAGGTGCTGCATGCCGCGACGATT
GTGCCGCCGGGGCGGGCGCT

Product: potassium-tellurite ethidium and proflavin transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MNKTQTPRQVLNLPAGYFGMVLGTIGMGFAWRYASTLWPVSRSIGDGLVTLAMAMWVLLSMAFISRAIRFPASVLREMRH
PVSSSFVSLFPATTLLVAIGLAPWCRPLAIGLFVPGVALQLAYAAWQSGGLWRGNHPREATTPGLYLPTVANNFISAMAC
GALGFSDAGLVFLGAGVFSWLSLEPAILQRLRSAGELPTPLRTSLGIQLAPALVACSAWLSVNGGEADTFAKLLFGYGLL
QLLFMLRLMPWYLRQPFNASFWSFSFGISALATTGLHLGQARGDGFFHHLAMPLFIFSNLVVGLLLLRTALLLVSGKLLL
QVDRETLLNKKEGS

Sequences:

>Translated_334_residues
MNKTQTPRQVLNLPAGYFGMVLGTIGMGFAWRYASTLWPVSRSIGDGLVTLAMAMWVLLSMAFISRAIRFPASVLREMRH
PVSSSFVSLFPATTLLVAIGLAPWCRPLAIGLFVPGVALQLAYAAWQSGGLWRGNHPREATTPGLYLPTVANNFISAMAC
GALGFSDAGLVFLGAGVFSWLSLEPAILQRLRSAGELPTPLRTSLGIQLAPALVACSAWLSVNGGEADTFAKLLFGYGLL
QLLFMLRLMPWYLRQPFNASFWSFSFGISALATTGLHLGQARGDGFFHHLAMPLFIFSNLVVGLLLLRTALLLVSGKLLL
QVDRETLLNKKEGS
>Mature_334_residues
MNKTQTPRQVLNLPAGYFGMVLGTIGMGFAWRYASTLWPVSRSIGDGLVTLAMAMWVLLSMAFISRAIRFPASVLREMRH
PVSSSFVSLFPATTLLVAIGLAPWCRPLAIGLFVPGVALQLAYAAWQSGGLWRGNHPREATTPGLYLPTVANNFISAMAC
GALGFSDAGLVFLGAGVFSWLSLEPAILQRLRSAGELPTPLRTSLGIQLAPALVACSAWLSVNGGEADTFAKLLFGYGLL
QLLFMLRLMPWYLRQPFNASFWSFSFGISALATTGLHLGQARGDGFFHHLAMPLFIFSNLVVGLLLLRTALLLVSGKLLL
QVDRETLLNKKEGS

Specific function: Responsible for potassium tellurite resistance when present in high copy number, probably by increasing the reduction rate of tellurite to metallic tellurium within the bacterium. Otherwise, phenotypically silent [H]

COG id: COG1275

COG function: function code P; Tellurite resistance protein and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family [H]

Homologues:

Organism=Escherichia coli, GI1787699, Length=324, Percent_Identity=77.4691358024691, Blast_Score=488, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004695
- InterPro:   IPR011552 [H]

Pfam domain/function: PF03595 C4dic_mal_tran [H]

EC number: NA

Molecular weight: Translated: 36133; Mature: 36133

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTQTPRQVLNLPAGYFGMVLGTIGMGFAWRYASTLWPVSRSIGDGLVTLAMAMWVLLS
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAFISRAIRFPASVLREMRHPVSSSFVSLFPATTLLVAIGLAPWCRPLAIGLFVPGVALQ
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYAAWQSGGLWRGNHPREATTPGLYLPTVANNFISAMACGALGFSDAGLVFLGAGVFSW
HHHHHHHCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LSLEPAILQRLRSAGELPTPLRTSLGIQLAPALVACSAWLSVNGGEADTFAKLLFGYGLL
HCCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QLLFMLRLMPWYLRQPFNASFWSFSFGISALATTGLHLGQARGDGFFHHLAMPLFIFSNL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VVGLLLLRTALLLVSGKLLLQVDRETLLNKKEGS
HHHHHHHHHHHHHHCCHHHEEECHHHHCCCCCCC
>Mature Secondary Structure
MNKTQTPRQVLNLPAGYFGMVLGTIGMGFAWRYASTLWPVSRSIGDGLVTLAMAMWVLLS
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MAFISRAIRFPASVLREMRHPVSSSFVSLFPATTLLVAIGLAPWCRPLAIGLFVPGVALQ
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAYAAWQSGGLWRGNHPREATTPGLYLPTVANNFISAMACGALGFSDAGLVFLGAGVFSW
HHHHHHHCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LSLEPAILQRLRSAGELPTPLRTSLGIQLAPALVACSAWLSVNGGEADTFAKLLFGYGLL
HCCCHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
QLLFMLRLMPWYLRQPFNASFWSFSFGISALATTGLHLGQARGDGFFHHLAMPLFIFSNL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
VVGLLLLRTALLLVSGKLLLQVDRETLLNKKEGS
HHHHHHHHHHHHHHCCHHHEEECHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2060788; 9097039; 9278503; 8169225 [H]