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The map label for this gene is dppA [H]

Identifier: 238894956

GI number: 238894956

Start: 2844643

End: 2846241

Strand: Reverse

Name: dppA [H]

Synonym: KP1_2981

Alternate gene names: 238894956

Gene position: 2846241-2844643 (Counterclockwise)

Preceding gene: 238894958

Following gene: 238894955

Centisome position: 54.23

GC content: 55.66

Gene sequence:

>1599_bases
ATGTCTACAGGGAAAACTACGCTGGCGCTGCTGCTGAGCGCACTGCTGCCGGCCGGCGCCGCCTGGGCCGCAGGCAATGA
CACTCTGGTCTACTGCTCAGAAGCCTCTCCGGAGTCCTTCAATCCGCAGATCGCCAGCTCCGGTCCGTCGTTCGTCGCCA
GCTCGCAGGTACTGTATAACCGTCTGGTGAGCTTTGACCCGGTGAAAAATACGCCGATCCCGTCGCTGGCCACCGAGTGG
CACGTCTCTGAGGATGGCAAAACCTGGACCTTTACTCTGCGTCAGGGGGTGAAGTTCAACAGCAACAAATTCTTCAAACC
GACCCGCGATTTTAACGCCGACGACGTTCTGTTCTCCGTGCTGCGCCAGATGGATCCTCAGCATCCTTATCACAAGGTAT
CGCAGGGGAACTATGAATACTTCCACGACGTGGGCCTCGATAAGCTGATTAAATCGGTGAAAAAGGTGGATGATTACCAT
GTCCAGTTCGAGCTCAACGAGCCGAACTCGGCGTTTCTTGCCGACTGGGGCATGGACTTCGCCTCTATTCTGTCGGCAGA
GTATGGTGAGGCGATGCTGAAGAAAGGAACGCCGGAAAACGTTGATAACTGGCCTGTCGGTACCGGACCGTATGCGCTGC
AGCAGTATAAAGTGGATTCGCAAATCCGCTATATTGCCAATCCCCACTATTGGGAAGGCGAGGTACCGACCAAGCACCTG
ATCTTCTCCATTACGCCGAACGTCGAGACTCGTCTGGCGAAACTGCAGACCAACGAGTGCCAGATTATTCCCGCGCCGTC
GCCGGTACAGTTCCCGGTGATTAAGGGCAATAAAGATCTGGCGCTGCATGCGGTTGAGGCGCTGAACGTCGGCTATCTGG
CGTTTAACACCGAGAAAAAACCGTTTGATAATGTGCTGGTGCGCCAGGCGTTAAACTACGCTACCGACAAGCAGGCGATC
GTCAAGGCGGTATTCCTCGATTCCGGCAGCGTGGCGAAATCACCGATCCCGTCGACGATGCTCGGGTATAAGAAAGATCT
CCCGGACTATGACTACGATCCGCAGAAAGCCAAAGCGCTGCTCAAGCAGGCGGGTCTGGAGCAAGGCGCGGAAGTGACCC
TGTGGTCAATGCCGGTCCAGCGCCCCTACAACCCAAACTCAAAACGCATTGCCGAAATGATCCAAAACGACTGGGCGAAA
GTGGGGGTGAAAGCCAAAATTGTCAGCTATGAATGGGGCGAATACCTTGCCGGTATGCGTAAAGGGGAGCACGACAGCGC
CCTGTATGGCTGGATGTCGGACAACGGCGATCCGGACAACTTTGCTGGCACATTGCTCAGCTGTGATAATATCCAGACCG
GCTCCAACGCCGCCCGCTGGTGTGATAAATCCTATGACGCGCTGGTAAAGAAAGCGCTGTTGGTGAGCGATCCGCAGGCG
CGGGCCAAACTCTACGAACAGGCGCAGGAGATTTTTTATCAGCAGGCGCCATGGATCACCCTGGCGACCGGGAAAACCTT
CTATGCGACGCGCAGCAACGTCAGCGGCTACACCGTCAGCATGATGGGGAGCGATTTTTCCAAAGCGAAGCTGAATTAA

Upstream 100 bases:

>100_bases
CACGCGTTTTGCATAAGGTGATAGCCATTGATTATTTGCCGCCGTCAGGCGGCTGTGCTGTTATTACTGTTCTTATAATC
AATAATCAGGACTTATAACC

Downstream 100 bases:

>100_bases
GCGAAAGGAGAACAGGATGGCACATCTGGATGAGGTTATCGTCAAAGTCGATGACACCCTGGCCGAGGGCGTTATCGCGC
ATATGAATGAGCTGCTAATC

Product: dipeptide transport protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MSTGKTTLALLLSALLPAGAAWAAGNDTLVYCSEASPESFNPQIASSGPSFVASSQVLYNRLVSFDPVKNTPIPSLATEW
HVSEDGKTWTFTLRQGVKFNSNKFFKPTRDFNADDVLFSVLRQMDPQHPYHKVSQGNYEYFHDVGLDKLIKSVKKVDDYH
VQFELNEPNSAFLADWGMDFASILSAEYGEAMLKKGTPENVDNWPVGTGPYALQQYKVDSQIRYIANPHYWEGEVPTKHL
IFSITPNVETRLAKLQTNECQIIPAPSPVQFPVIKGNKDLALHAVEALNVGYLAFNTEKKPFDNVLVRQALNYATDKQAI
VKAVFLDSGSVAKSPIPSTMLGYKKDLPDYDYDPQKAKALLKQAGLEQGAEVTLWSMPVQRPYNPNSKRIAEMIQNDWAK
VGVKAKIVSYEWGEYLAGMRKGEHDSALYGWMSDNGDPDNFAGTLLSCDNIQTGSNAARWCDKSYDALVKKALLVSDPQA
RAKLYEQAQEIFYQQAPWITLATGKTFYATRSNVSGYTVSMMGSDFSKAKLN

Sequences:

>Translated_532_residues
MSTGKTTLALLLSALLPAGAAWAAGNDTLVYCSEASPESFNPQIASSGPSFVASSQVLYNRLVSFDPVKNTPIPSLATEW
HVSEDGKTWTFTLRQGVKFNSNKFFKPTRDFNADDVLFSVLRQMDPQHPYHKVSQGNYEYFHDVGLDKLIKSVKKVDDYH
VQFELNEPNSAFLADWGMDFASILSAEYGEAMLKKGTPENVDNWPVGTGPYALQQYKVDSQIRYIANPHYWEGEVPTKHL
IFSITPNVETRLAKLQTNECQIIPAPSPVQFPVIKGNKDLALHAVEALNVGYLAFNTEKKPFDNVLVRQALNYATDKQAI
VKAVFLDSGSVAKSPIPSTMLGYKKDLPDYDYDPQKAKALLKQAGLEQGAEVTLWSMPVQRPYNPNSKRIAEMIQNDWAK
VGVKAKIVSYEWGEYLAGMRKGEHDSALYGWMSDNGDPDNFAGTLLSCDNIQTGSNAARWCDKSYDALVKKALLVSDPQA
RAKLYEQAQEIFYQQAPWITLATGKTFYATRSNVSGYTVSMMGSDFSKAKLN
>Mature_531_residues
STGKTTLALLLSALLPAGAAWAAGNDTLVYCSEASPESFNPQIASSGPSFVASSQVLYNRLVSFDPVKNTPIPSLATEWH
VSEDGKTWTFTLRQGVKFNSNKFFKPTRDFNADDVLFSVLRQMDPQHPYHKVSQGNYEYFHDVGLDKLIKSVKKVDDYHV
QFELNEPNSAFLADWGMDFASILSAEYGEAMLKKGTPENVDNWPVGTGPYALQQYKVDSQIRYIANPHYWEGEVPTKHLI
FSITPNVETRLAKLQTNECQIIPAPSPVQFPVIKGNKDLALHAVEALNVGYLAFNTEKKPFDNVLVRQALNYATDKQAIV
KAVFLDSGSVAKSPIPSTMLGYKKDLPDYDYDPQKAKALLKQAGLEQGAEVTLWSMPVQRPYNPNSKRIAEMIQNDWAKV
GVKAKIVSYEWGEYLAGMRKGEHDSALYGWMSDNGDPDNFAGTLLSCDNIQTGSNAARWCDKSYDALVKKALLVSDPQAR
AKLYEQAQEIFYQQAPWITLATGKTFYATRSNVSGYTVSMMGSDFSKAKLN

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=521, Percent_Identity=54.89443378119, Blast_Score=581, Evalue=1e-167,
Organism=Escherichia coli, GI1787551, Length=525, Percent_Identity=34.8571428571429, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1787052, Length=531, Percent_Identity=29.5668549905838, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787762, Length=526, Percent_Identity=26.2357414448669, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787495, Length=533, Percent_Identity=26.4540337711069, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1789887, Length=529, Percent_Identity=24.1965973534972, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789397, Length=515, Percent_Identity=26.0194174757282, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081878, Length=523, Percent_Identity=23.9005736137667, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59179; Mature: 59048

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGKTTLALLLSALLPAGAAWAAGNDTLVYCSEASPESFNPQIASSGPSFVASSQVLYN
CCCCHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
RLVSFDPVKNTPIPSLATEWHVSEDGKTWTFTLRQGVKFNSNKFFKPTRDFNADDVLFSV
HHHCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCEECCCCCCCCCCCCCHHHHHHHH
LRQMDPQHPYHKVSQGNYEYFHDVGLDKLIKSVKKVDDYHVQFELNEPNSAFLADWGMDF
HHHCCCCCCCHHHCCCCCHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCH
ASILSAEYGEAMLKKGTPENVDNWPVGTGPYALQQYKVDSQIRYIANPHYWEGEVPTKHL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCCCEEEECCCCCCCCCCCCEEE
IFSITPNVETRLAKLQTNECQIIPAPSPVQFPVIKGNKDLALHAVEALNVGYLAFNTEKK
EEEECCCHHHHHHHEECCCEEEEECCCCCEEEEEECCCCEEEEEHHHHCEEEEEEECCCC
PFDNVLVRQALNYATDKQAIVKAVFLDSGSVAKSPIPSTMLGYKKDLPDYDYDPQKAKAL
CHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
LKQAGLEQGAEVTLWSMPVQRPYNPNSKRIAEMIQNDWAKVGVKAKIVSYEWGEYLAGMR
HHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHC
KGEHDSALYGWMSDNGDPDNFAGTLLSCDNIQTGSNAARWCDKSYDALVKKALLVSDPQA
CCCCCCEEEEECCCCCCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAKLYEQAQEIFYQQAPWITLATGKTFYATRSNVSGYTVSMMGSDFSKAKLN
HHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
STGKTTLALLLSALLPAGAAWAAGNDTLVYCSEASPESFNPQIASSGPSFVASSQVLYN
CCCHHHHHHHHHHHHCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
RLVSFDPVKNTPIPSLATEWHVSEDGKTWTFTLRQGVKFNSNKFFKPTRDFNADDVLFSV
HHHCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCEECCCCCCCCCCCCCHHHHHHHH
LRQMDPQHPYHKVSQGNYEYFHDVGLDKLIKSVKKVDDYHVQFELNEPNSAFLADWGMDF
HHHCCCCCCCHHHCCCCCHHHHHCCHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCH
ASILSAEYGEAMLKKGTPENVDNWPVGTGPYALQQYKVDSQIRYIANPHYWEGEVPTKHL
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHEECCCCCEEEECCCCCCCCCCCCEEE
IFSITPNVETRLAKLQTNECQIIPAPSPVQFPVIKGNKDLALHAVEALNVGYLAFNTEKK
EEEECCCHHHHHHHEECCCEEEEECCCCCEEEEEECCCCEEEEEHHHHCEEEEEEECCCC
PFDNVLVRQALNYATDKQAIVKAVFLDSGSVAKSPIPSTMLGYKKDLPDYDYDPQKAKAL
CHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
LKQAGLEQGAEVTLWSMPVQRPYNPNSKRIAEMIQNDWAKVGVKAKIVSYEWGEYLAGMR
HHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEEECHHHHHHHHC
KGEHDSALYGWMSDNGDPDNFAGTLLSCDNIQTGSNAARWCDKSYDALVKKALLVSDPQA
CCCCCCEEEEECCCCCCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAKLYEQAQEIFYQQAPWITLATGKTFYATRSNVSGYTVSMMGSDFSKAKLN
HHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]