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The map label for this gene is catB [H]

Identifier: 238894918

GI number: 238894918

Start: 2803590

End: 2804777

Strand: Reverse

Name: catB [H]

Synonym: KP1_2941

Alternate gene names: 238894918

Gene position: 2804777-2803590 (Counterclockwise)

Preceding gene: 238894920

Following gene: 238894917

Centisome position: 53.44

GC content: 61.62

Gene sequence:

>1188_bases
TTGTCAATGGCACAGACCCCCGTTATGGATGTGGGTACAAAAAGTTATATATCTCATCAGGAACAGAAAATGACTGCCAC
CGTAGAGCAAATCGAGAGCTGGATTGTGGATGTCCCGACCATCCGGCCGCATAAATTGTCGATGACCACCATGGGCTGCC
AGTCGCTGGTGATCGTGCGCCTTACCCGTTCCGACGGCATCTGCGGCATCGGCGAAGCCACCACCATCGGCGGCTTGAGC
TATGGCGTTGAGAGCCCCGAGGCCATCTCGTCGGCGATCACCCATTATCTGACGCCGCTGTTGAAAGGGCAGCCGGCCGA
TAACCTGAATGCGCTGACCGCCCGCATGAACGGCGCCATTAAAGGCAACACCTTTGCGAAGTCCGCCATCGAAACCGCGC
TGCTCGACGCTCAGGGCAAAGCCTTAGGTCTGCCGATATCAGCCCTGCTCGGCGGCGCGCTGCAAACGGCGTTGCCGGTG
CTGTGGACCTTAGCCAGCGGCGATACCGCGAAAGATATCGCTGAAGGAGAAAAACTGTTGGCCGAAGGCCGCCACCGGGC
GTTCAAACTGAAGATCGGCGCGCGTGAACTCGCCACCGACCTGCGTCATACCCGCGCCATCGTTGAAGCGTTAGGCGACC
GCGCCAGCATCCGTGTCGACGTCAACCAGGCCTGGGACGCCGCCACCGGCGCGAAAGGCTGCCGCGAACTGGCGGCAATG
GGCGTCGATCTTATCGAACAGCCGGTCAGCGCCCACGATAATGCCGCCCTGGTGCGGTTAAGCCAGCAAATTGAAACCGC
GATCCTCGCGGATGAAGCGGTCGCGACCGCTTACGATGGTTATCAGCTGGCGCAGCAGGGCTTTACCGGCGCTTACGCGC
TGAAAATCGCCAAAGCCGGGGGGCCGAACAGCGTGCTGGCGCTGGCCCGCGTCGCGCAGGCGGCAGGGATTGGCCTGTAC
GGCGGCACCATGCTGGAAGGCACCGTAGGGACCGTGGCTTCTCTGCACGCCTGGTCGACGCTGCCGCTGCAGTGGGGTAC
CGAGATGTTCGGCCCGCTGTTGCTGAAAGACGATATTGTCAGCGTGCCGCTCACCTTTGCCGACGGTCAGGTGGCGCTGC
CGCAAACGCCGGGACTTGGCGTCGAGCTGGATGAAGACAAACTGCATTTTTATACCCGCCAGCCGTAG

Upstream 100 bases:

>100_bases
TACCACCACGATCACATTAATAACCGTCTTTTAACAAACGCGTCGATAATCGCACAACATTTCGATTATCGCCGTTGACC
ATCCGCCAGGCTGAACCCTA

Downstream 100 bases:

>100_bases
CGGGGAACAGGAGAAAAAAATGTTATTTAAAGTGGAGATGATCGTCAATATTCCGCCTGGCTTTCCCGCCAACGAGGCGG
AGGAAATAAAACAACGCGAA

Product: L-Ala-D/L-Glu epimerase

Products: NA

Alternate protein names: Cis,cis-muconate lactonizing enzyme I; MLE; Muconate cycloisomerase I [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSMAQTPVMDVGTKSYISHQEQKMTATVEQIESWIVDVPTIRPHKLSMTTMGCQSLVIVRLTRSDGICGIGEATTIGGLS
YGVESPEAISSAITHYLTPLLKGQPADNLNALTARMNGAIKGNTFAKSAIETALLDAQGKALGLPISALLGGALQTALPV
LWTLASGDTAKDIAEGEKLLAEGRHRAFKLKIGARELATDLRHTRAIVEALGDRASIRVDVNQAWDAATGAKGCRELAAM
GVDLIEQPVSAHDNAALVRLSQQIETAILADEAVATAYDGYQLAQQGFTGAYALKIAKAGGPNSVLALARVAQAAGIGLY
GGTMLEGTVGTVASLHAWSTLPLQWGTEMFGPLLLKDDIVSVPLTFADGQVALPQTPGLGVELDEDKLHFYTRQP

Sequences:

>Translated_395_residues
MSMAQTPVMDVGTKSYISHQEQKMTATVEQIESWIVDVPTIRPHKLSMTTMGCQSLVIVRLTRSDGICGIGEATTIGGLS
YGVESPEAISSAITHYLTPLLKGQPADNLNALTARMNGAIKGNTFAKSAIETALLDAQGKALGLPISALLGGALQTALPV
LWTLASGDTAKDIAEGEKLLAEGRHRAFKLKIGARELATDLRHTRAIVEALGDRASIRVDVNQAWDAATGAKGCRELAAM
GVDLIEQPVSAHDNAALVRLSQQIETAILADEAVATAYDGYQLAQQGFTGAYALKIAKAGGPNSVLALARVAQAAGIGLY
GGTMLEGTVGTVASLHAWSTLPLQWGTEMFGPLLLKDDIVSVPLTFADGQVALPQTPGLGVELDEDKLHFYTRQP
>Mature_394_residues
SMAQTPVMDVGTKSYISHQEQKMTATVEQIESWIVDVPTIRPHKLSMTTMGCQSLVIVRLTRSDGICGIGEATTIGGLSY
GVESPEAISSAITHYLTPLLKGQPADNLNALTARMNGAIKGNTFAKSAIETALLDAQGKALGLPISALLGGALQTALPVL
WTLASGDTAKDIAEGEKLLAEGRHRAFKLKIGARELATDLRHTRAIVEALGDRASIRVDVNQAWDAATGAKGCRELAAMG
VDLIEQPVSAHDNAALVRLSQQIETAILADEAVATAYDGYQLAQQGFTGAYALKIAKAGGPNSVLALARVAQAAGIGLYG
GTMLEGTVGTVASLHAWSTLPLQWGTEMFGPLLLKDDIVSVPLTFADGQVALPQTPGLGVELDEDKLHFYTRQP

Specific function: Catalyzes a syn cycloisomerization [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994953, Length=366, Percent_Identity=25.9562841530055, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87081876, Length=329, Percent_Identity=28.2674772036474, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013370
- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =5.5.1.1 [H]

Molecular weight: Translated: 41548; Mature: 41417

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMAQTPVMDVGTKSYISHQEQKMTATVEQIESWIVDVPTIRPHKLSMTTMGCQSLVIVR
CCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCEEEEEE
LTRSDGICGIGEATTIGGLSYGVESPEAISSAITHYLTPLLKGQPADNLNALTARMNGAI
EECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
KGNTFAKSAIETALLDAQGKALGLPISALLGGALQTALPVLWTLASGDTAKDIAEGEKLL
CCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
AEGRHRAFKLKIGARELATDLRHTRAIVEALGDRASIRVDVNQAWDAATGAKGCRELAAM
HCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHH
GVDLIEQPVSAHDNAALVRLSQQIETAILADEAVATAYDGYQLAQQGFTGAYALKIAKAG
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCC
GPNSVLALARVAQAAGIGLYGGTMLEGTVGTVASLHAWSTLPLQWGTEMFGPLLLKDDIV
CCHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCHHHCHHHHCCEEECCCCE
SVPLTFADGQVALPQTPGLGVELDEDKLHFYTRQP
EEEEEECCCEEECCCCCCCCCEECCCCEEEEECCC
>Mature Secondary Structure 
SMAQTPVMDVGTKSYISHQEQKMTATVEQIESWIVDVPTIRPHKLSMTTMGCQSLVIVR
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCEEEEEE
LTRSDGICGIGEATTIGGLSYGVESPEAISSAITHYLTPLLKGQPADNLNALTARMNGAI
EECCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
KGNTFAKSAIETALLDAQGKALGLPISALLGGALQTALPVLWTLASGDTAKDIAEGEKLL
CCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHH
AEGRHRAFKLKIGARELATDLRHTRAIVEALGDRASIRVDVNQAWDAATGAKGCRELAAM
HCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHH
GVDLIEQPVSAHDNAALVRLSQQIETAILADEAVATAYDGYQLAQQGFTGAYALKIAKAG
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEEECCC
GPNSVLALARVAQAAGIGLYGGTMLEGTVGTVASLHAWSTLPLQWGTEMFGPLLLKDDIV
CCHHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHCCCCCHHHCHHHHCCEEECCCCE
SVPLTFADGQVALPQTPGLGVELDEDKLHFYTRQP
EEEEEECCCEEECCCCCCCCCEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3609743; 2449420; 2215699; 3612800; 7500361 [H]