Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 238894793

GI number: 238894793

Start: 2675380

End: 2676480

Strand: Direct

Name: namA [H]

Synonym: KP1_2803

Alternate gene names: 238894793

Gene position: 2675380-2676480 (Clockwise)

Preceding gene: 238894792

Following gene: 238894796

Centisome position: 50.97

GC content: 64.4

Gene sequence:

>1101_bases
ATGAGTCATCTTTTTAGCGCGACGCGAATTGGTCAACTCACCCTTGATAACCGTATCGTTATCGCCCCGATGTGTCAGTA
CTCCGCCGACGAGGGTAAGGCGACCTCCTGGCACCGGATCCATCTTGGCCAACTGGCTTTCTCCGGCGCCGGCCTGTTAA
TTCTGGAAGCCACGGCGGTAGAGCCTGCGGGGCGTATCTCCCCGGGGGATCTGGGGCTGTGGGATGATGAAACCGAAAAC
GCCCTGCGCGGCGTAGTCGAAGATATTCGGGCCTGGTCGCCGATCCGTCTGGGGATCCAGCTGGGTCATGCCGGACGCAA
AGCATCCTGCGCCGCCCCCTGGCAGGGAGGCCATCAGCTGGCGCTCAACGATGGTGGCTGGCAGACCGTCGCCCCTTCCG
CCGTGGCGTTTCACGATGGCGATCGCGCCCCCGCTGAACTGAGCCATGCCGATCTGGCGCGCATCAAAGCGGCCTTCGTC
GCCAGCGCGCTGCGCGCCCAGCGGCTGGGCTTTGAGCTGATTGAACTGCACGCCGCCCACGGCTATCTGCTGCACCAGTT
TCTCTCGCCGCTCAGCAACCAGCGCCGCGACGAGTACGGCGGTTCGCTGGAGAACCGAATGCGCTATCCGCTGGAAGTCT
TTAAGGCGATCCGCGAGGCAGTGGGCAACACCATGGCGGTGGGCGTCAGGCTGTCGGCTACCGACTGGGTCGAAGGCGGC
TGGGACTGCGAGCAGTCCATTAAGTTTAGCCAGCAGCTGGAAACGCTGGGCAGTGACTATATTCACGTCTCCAGCGGCGG
TTTGTCGCCGCAGCAGGCGATCACCGTTGGGCCGGGATACCAGTTGCCTTTCGCCCGCGATATTCGCCAGCAGGTAGCCA
TCCCGGTGATTGGCGTGGGGCTGATCACCGACCCGCAGCAGGCGGAAGCGGCGCTGGAGAATGGCGATGCCGACCTGATC
GCCCTCGCCCGCGCGGTACTCTACGATCCGCACTGGCCGTGGCACGCAGCGGCCAGCCTTGGCGCCCAGGTCCGTGTGCC
GTCGCAGTATTTGCGCTCGGAGCCGCACGGCCTGAAAGGCACCCTGCTGCCAAACCGTTGA

Upstream 100 bases:

>100_bases
CTTAAGCGCAATATCCGAATACTGGGGGGGTGAACAGGCGTGCTATAAACAGCAACTGTCCGTCCCCTGCACGACCACGT
TTAACATTTACGAGGTATTC

Downstream 100 bases:

>100_bases
ACCCACGGCGGGCATAAAAAAGGGGTATCGTAAGATACCCCTGAGCAGGATGTTATTGCGGTCCATGTGCCGGGCGGCGG
CGACGCTTTGCCGGCCTACA

Product: putative NADH:flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSHLFSATRIGQLTLDNRIVIAPMCQYSADEGKATSWHRIHLGQLAFSGAGLLILEATAVEPAGRISPGDLGLWDDETEN
ALRGVVEDIRAWSPIRLGIQLGHAGRKASCAAPWQGGHQLALNDGGWQTVAPSAVAFHDGDRAPAELSHADLARIKAAFV
ASALRAQRLGFELIELHAAHGYLLHQFLSPLSNQRRDEYGGSLENRMRYPLEVFKAIREAVGNTMAVGVRLSATDWVEGG
WDCEQSIKFSQQLETLGSDYIHVSSGGLSPQQAITVGPGYQLPFARDIRQQVAIPVIGVGLITDPQQAEAALENGDADLI
ALARAVLYDPHWPWHAAASLGAQVRVPSQYLRSEPHGLKGTLLPNR

Sequences:

>Translated_366_residues
MSHLFSATRIGQLTLDNRIVIAPMCQYSADEGKATSWHRIHLGQLAFSGAGLLILEATAVEPAGRISPGDLGLWDDETEN
ALRGVVEDIRAWSPIRLGIQLGHAGRKASCAAPWQGGHQLALNDGGWQTVAPSAVAFHDGDRAPAELSHADLARIKAAFV
ASALRAQRLGFELIELHAAHGYLLHQFLSPLSNQRRDEYGGSLENRMRYPLEVFKAIREAVGNTMAVGVRLSATDWVEGG
WDCEQSIKFSQQLETLGSDYIHVSSGGLSPQQAITVGPGYQLPFARDIRQQVAIPVIGVGLITDPQQAEAALENGDADLI
ALARAVLYDPHWPWHAAASLGAQVRVPSQYLRSEPHGLKGTLLPNR
>Mature_365_residues
SHLFSATRIGQLTLDNRIVIAPMCQYSADEGKATSWHRIHLGQLAFSGAGLLILEATAVEPAGRISPGDLGLWDDETENA
LRGVVEDIRAWSPIRLGIQLGHAGRKASCAAPWQGGHQLALNDGGWQTVAPSAVAFHDGDRAPAELSHADLARIKAAFVA
SALRAQRLGFELIELHAAHGYLLHQFLSPLSNQRRDEYGGSLENRMRYPLEVFKAIREAVGNTMAVGVRLSATDWVEGGW
DCEQSIKFSQQLETLGSDYIHVSSGGLSPQQAITVGPGYQLPFARDIRQQVAIPVIGVGLITDPQQAEAALENGDADLIA
LARAVLYDPHWPWHAAASLGAQVRVPSQYLRSEPHGLKGTLLPNR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=331, Percent_Identity=29.3051359516616, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787939, Length=345, Percent_Identity=30.4347826086957, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17559802, Length=201, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=248, Percent_Identity=28.2258064516129, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=185, Percent_Identity=31.3513513513514, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17540738, Length=246, Percent_Identity=27.2357723577236, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=174, Percent_Identity=31.6091954022989, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=175, Percent_Identity=32.5714285714286, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17566914, Length=101, Percent_Identity=42.5742574257426, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=245, Percent_Identity=28.1632653061224, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6321973, Length=246, Percent_Identity=29.2682926829268, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39580; Mature: 39449

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLFSATRIGQLTLDNRIVIAPMCQYSADEGKATSWHRIHLGQLAFSGAGLLILEATAV
CCCCCCHHHCCEEEECCEEEEEECCCCCCCCCCCCCEEEEEEHHEEECCCCEEEEEEECC
EPAGRISPGDLGLWDDETENALRGVVEDIRAWSPIRLGIQLGHAGRKASCAAPWQGGHQL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEE
ALNDGGWQTVAPSAVAFHDGDRAPAELSHADLARIKAAFVASALRAQRLGFELIELHAAH
EEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
GYLLHQFLSPLSNQRRDEYGGSLENRMRYPLEVFKAIREAVGNTMAVGVRLSATDWVEGG
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCC
WDCEQSIKFSQQLETLGSDYIHVSSGGLSPQQAITVGPGYQLPFARDIRQQVAIPVIGVG
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEE
LITDPQQAEAALENGDADLIALARAVLYDPHWPWHAAASLGAQVRVPSQYLRSEPHGLKG
ECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEECCHHHHCCCCCCCEE
TLLPNR
CCCCCC
>Mature Secondary Structure 
SHLFSATRIGQLTLDNRIVIAPMCQYSADEGKATSWHRIHLGQLAFSGAGLLILEATAV
CCCCCHHHCCEEEECCEEEEEECCCCCCCCCCCCCEEEEEEHHEEECCCCEEEEEEECC
EPAGRISPGDLGLWDDETENALRGVVEDIRAWSPIRLGIQLGHAGRKASCAAPWQGGHQL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEE
ALNDGGWQTVAPSAVAFHDGDRAPAELSHADLARIKAAFVASALRAQRLGFELIELHAAH
EEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
GYLLHQFLSPLSNQRRDEYGGSLENRMRYPLEVFKAIREAVGNTMAVGVRLSATDWVEGG
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCCEEEEEEEEECCCCCCCC
WDCEQSIKFSQQLETLGSDYIHVSSGGLSPQQAITVGPGYQLPFARDIRQQVAIPVIGVG
CCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHCCCEEEEE
LITDPQQAEAALENGDADLIALARAVLYDPHWPWHAAASLGAQVRVPSQYLRSEPHGLKG
ECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCEEECCHHHHCCCCCCCEE
TLLPNR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA