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The map label for this gene is rbsK [H]

Identifier: 238894764

GI number: 238894764

Start: 2646271

End: 2647143

Strand: Direct

Name: rbsK [H]

Synonym: KP1_2772

Alternate gene names: 238894764

Gene position: 2646271-2647143 (Clockwise)

Preceding gene: 238894761

Following gene: 238894766

Centisome position: 50.42

GC content: 58.88

Gene sequence:

>873_bases
ATGCGTGTTTACGTTACTGGTAATATTACCGTAGATGAAACCTGGTCCATTCCGGATATACCGAAAAAAGGAGCCTCCAT
TCACGGCGTTAAAGTGTCGCAGGATATCGGCGGTAAAGGCGCGAACCAGGCGATTATATTATCCCGCTGCGGAATAGAGA
CGCGTTTAATTGCCGCCACGGGAAATGACAGCAACGGCGCGTGGATCCGCCAGCAGATAAAAAATGAACCACTGACGCTA
CTACCCGACGGCCATTTCAATCAACATAGCGATACCTCGATTATTTTAAATAGCGCTGATGGCGACAACGCCATCATTAC
CACTACGGCGGCGGCCGATACATTCAGCCTGGATGAAATGATTCCGCATATGGCGGATGCCGTCGCTGGCGATATTCTGC
TACAGCAGGGCAATTTCTCCCTCGATAAAACGCGGGCGCTGTTCCAGTACGCCAGAAGCCGCGGCATGACGACGGTATTC
AACCCCTCACCTGTCAATCCTGACTTTTGCCATCTGTGGCCCCTCATCGACATCGCGGTGGTCAATGAATCCGAGGCCGA
GCTGCTCCAGCCATACGGGGTGAAAACCTTAGTGATTACCCAGGGCGCCGCAGGCGCCTGGCTGGTCCAGGAGGGCCAGC
GTCAGTTTTGTCCCGCCGTGCCCGCCGAGGCGCTTGATACTACCGGCGCGGGCGACACGTTCCTCGCCGTCATGTTGGCC
TCCGCCCTGCTGCGCGGCGTCGCGCCGGATGCGCTGGCGCTGGCGCACGCCAGTCGCGCTGCCGCCATTACGGTTAGCCG
CCGGGGGACGGTCAGCGCGTTTCCCGGCAGCCGTGAGCTCGCCGCCCTGTTAACCACGGACGGGGCGCGCTGA

Upstream 100 bases:

>100_bases
ACACCAATAACAGCCTTGCTTCGTGAAAAAATAGCTTGTATTGCATTCGTTTTTTCTGCTGAGATAGCAACCATCTTATC
CATCCTGTTAAGGGAACACT

Downstream 100 bases:

>100_bases
CCTACTTAAACAGCGGACGGTATGAATCGACGTTCGCTTTGGTTACCACCGTCGCCGGAACCAGAATGGTTTTCGGCACG
GTTTTACCCGACGTGATGCT

Product: carbohydrate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MRVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATGNDSNGAWIRQQIKNEPLTL
LPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEMIPHMADAVAGDILLQQGNFSLDKTRALFQYARSRGMTTVF
NPSPVNPDFCHLWPLIDIAVVNESEAELLQPYGVKTLVITQGAAGAWLVQEGQRQFCPAVPAEALDTTGAGDTFLAVMLA
SALLRGVAPDALALAHASRAAAITVSRRGTVSAFPGSRELAALLTTDGAR

Sequences:

>Translated_290_residues
MRVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATGNDSNGAWIRQQIKNEPLTL
LPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEMIPHMADAVAGDILLQQGNFSLDKTRALFQYARSRGMTTVF
NPSPVNPDFCHLWPLIDIAVVNESEAELLQPYGVKTLVITQGAAGAWLVQEGQRQFCPAVPAEALDTTGAGDTFLAVMLA
SALLRGVAPDALALAHASRAAAITVSRRGTVSAFPGSRELAALLTTDGAR
>Mature_290_residues
MRVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAATGNDSNGAWIRQQIKNEPLTL
LPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEMIPHMADAVAGDILLQQGNFSLDKTRALFQYARSRGMTTVF
NPSPVNPDFCHLWPLIDIAVVNESEAELLQPYGVKTLVITQGAAGAWLVQEGQRQFCPAVPAEALDTTGAGDTFLAVMLA
SALLRGVAPDALALAHASRAAAITVSRRGTVSAFPGSRELAALLTTDGAR

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=290, Percent_Identity=28.2758620689655, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=29.2763157894737, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI87082343, Length=307, Percent_Identity=25.7328990228013, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=31, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=28.3387622149837, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583886, Length=311, Percent_Identity=26.3665594855305, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30643; Mature: 30643

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAAT
CEEEEEECEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEEE
GNDSNGAWIRQQIKNEPLTLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEM
CCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHH
IPHMADAVAGDILLQQGNFSLDKTRALFQYARSRGMTTVFNPSPVNPDFCHLWPLIDIAV
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEECCCEEEEEE
VNESEAELLQPYGVKTLVITQGAAGAWLVQEGQRQFCPAVPAEALDTTGAGDTFLAVMLA
ECCCHHHHHCCCCCEEEEEECCCCCEEEEECCCHHCCCCCCHHHHCCCCCCHHHHHHHHH
SALLRGVAPDALALAHASRAAAITVSRRGTVSAFPGSRELAALLTTDGAR
HHHHHCCCCHHHHHHHCCCEEEEEEECCCEEEECCCCCCEEEEEECCCCC
>Mature Secondary Structure
MRVYVTGNITVDETWSIPDIPKKGASIHGVKVSQDIGGKGANQAIILSRCGIETRLIAAT
CEEEEEECEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCEEEEEEE
GNDSNGAWIRQQIKNEPLTLLPDGHFNQHSDTSIILNSADGDNAIITTTAAADTFSLDEM
CCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCHHHH
IPHMADAVAGDILLQQGNFSLDKTRALFQYARSRGMTTVFNPSPVNPDFCHLWPLIDIAV
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCEECCCEEEEEE
VNESEAELLQPYGVKTLVITQGAAGAWLVQEGQRQFCPAVPAEALDTTGAGDTFLAVMLA
ECCCHHHHHCCCCCEEEEEECCCCCEEEEECCCHHCCCCCCHHHHCCCCCCHHHHHHHHH
SALLRGVAPDALALAHASRAAAITVSRRGTVSAFPGSRELAALLTTDGAR
HHHHHCCCCHHHHHHHCCCEEEEEEECCCEEEECCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]