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The map label for this gene is pgtP [H]

Identifier: 238894759

GI number: 238894759

Start: 2641402

End: 2642793

Strand: Direct

Name: pgtP [H]

Synonym: KP1_2767

Alternate gene names: 238894759

Gene position: 2641402-2642793 (Clockwise)

Preceding gene: 238894754

Following gene: 238894761

Centisome position: 50.33

GC content: 54.24

Gene sequence:

>1392_bases
ATGTTATCATTATTAAAAAAAGGCCCGTCGGCGAATAAAGTTCCTGCTGAGAAAATTCAGGCAACCTATGGTCGATACCG
TATGCAGGCGCTGCTAAGCGTATTTCTGGGATACCTGGCGTACTATATCGTGCGCAATAACTTCACCTTATCCACGCCCT
ATCTGAAAGAACAGTTAGACCTCAGCGCCACGCAGATCGGTTTGCTCAGCAGCTGTATGCTCATCGCCTACGGGATCAGT
AAAGGCGTAATGAGCAGCCTCGCGGATAAAGCCAGCCCGAAAGTCTTTATGGCCTGTGGCCTGGTGCTGTGCGCCATCGT
CAACGTCGGGTTAGGATTCAGTACCGCATTCTGGGTCTTCGCTGCGCTGGTTGTCCTGAACGGCCTGTTTCAGGGTATGG
GGGTCGGCCCCTCTTTTATTACTATTGCGAACTGGTTCCCGCGCCGTGAGCGTGGCCGCGTTGGGGCGTTCTGGAACATT
TCCCATAACGTCGGCGGCGGAATTGTCGCCCCGATCGTCGGCGCCGCATTCGCCATTCTCGGCACCGAGCACTGGCAGAG
CGCCAGCTACATTGTACCGGCCTGCGTGGCGGTGGTATTCGCCATTAGCGTACTGGTACTGGGTAAGGGTTCGCCGCGCG
AGGAAGGTCTGCCTTCGCTGGCAGAGATGATGCCGGAAGAGAAAGTGGTGCTGAAGACCAAACACGGCCAGAAAGCGCCG
GAGAACATGAGCGCATTTCAGATCTTCTGTACCTACGTACTGCGTAACAAAAACGCCTGGTATGTCTCCTTTGTGGATGT
GTTTGTCTATATGGTGCGTTTCGGCATGATCAGCTGGCTGCCAATTTACCTGCTGACGGTGAAACATTTTTCCAAAGAAC
AAATGAGCGTCGCATTCCTGTTTTTTGAGTGGGCGGCAATTCCGTCTACTCTGCTGGCCGGCTGGCTCTCCGACAAGCTG
TTTAAAGGGCGCCGGATGCCGTTAGCTATAATCTGTATGACGCTAATCTTCATCTGTCTGATTGGCTACTGGAAAAGCGA
ATCTCTGCTGATGGTCACGGTATTCGCGGCGATTGTGGGCTGCCTTATTTATGTCCCGCAGTTTCTGGCCTCGGTCCAGA
CCATGGAAATCGTCCCCAGCTTTGCCGTCGGTTCAGCCGTGGGTCTGCGCGGATTTATGAGCTATATCTTTGGCGCATCG
TTAGGCACCAGCCTGTTCGGCGTAATGGTCGATAAAATGGGCTGGCACGGCGGGTTCTATCTGCTGATGGGCGGGATCGT
CTGCTGCATACTCTTCTGCTACCTCTCTCATCGCGGCGCGCTGGAACTTGAGCAACAGCGTAAAAACACCGAGCAGGAAG
AGGCCCGGCTGGCACTGGCTAACGCACAGTAA

Upstream 100 bases:

>100_bases
ATTTTGACTCATTTCGTCGATTTGAATTTTTTAGCCGCTTATTTCACCCTTCGGGGTAATTACTCCTGATGTTCATATCA
ATATAAATACAGGTGACGAC

Downstream 100 bases:

>100_bases
GCGCCTGAACCCCGGTAAAAGAGCCAGCAAGCTGGCTCTTTTGTCGTTGAGAGAGGAATAGATGTCCGCGGCGGCTTCCG
ACAGCGGTATAAAGCAAGTA

Product: phosphoglycerate transporter protein

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MLSLLKKGPSANKVPAEKIQATYGRYRMQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGTEHWQSASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAP
ENMSAFQIFCTYVLRNKNAWYVSFVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAIICMTLIFICLIGYWKSESLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKMGWHGGFYLLMGGIVCCILFCYLSHRGALELEQQRKNTEQEEARLALANAQ

Sequences:

>Translated_463_residues
MLSLLKKGPSANKVPAEKIQATYGRYRMQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGTEHWQSASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAP
ENMSAFQIFCTYVLRNKNAWYVSFVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAIICMTLIFICLIGYWKSESLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKMGWHGGFYLLMGGIVCCILFCYLSHRGALELEQQRKNTEQEEARLALANAQ
>Mature_463_residues
MLSLLKKGPSANKVPAEKIQATYGRYRMQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGIS
KGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSTAFWVFAALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
SHNVGGGIVAPIVGAAFAILGTEHWQSASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAP
ENMSAFQIFCTYVLRNKNAWYVSFVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKL
FKGRRMPLAIICMTLIFICLIGYWKSESLLMVTVFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGAS
LGTSLFGVMVDKMGWHGGFYLLMGGIVCCILFCYLSHRGALELEQQRKNTEQEEARLALANAQ

Specific function: The phosphoglycerate transporter protein is a part of the PGT transport system. It is the membrane bound transporter for phosphoglycerate into salmonella [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=411, Percent_Identity=26.2773722627737, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4503847, Length=411, Percent_Identity=26.2773722627737, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI256219483, Length=411, Percent_Identity=26.2773722627737, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI256219543, Length=297, Percent_Identity=29.2929292929293, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI223717983, Length=433, Percent_Identity=23.7875288683603, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI38093649, Length=413, Percent_Identity=24.455205811138, Blast_Score=83, Evalue=7e-16,
Organism=Escherichia coli, GI1788573, Length=464, Percent_Identity=36.6379310344828, Blast_Score=305, Evalue=4e-84,
Organism=Escherichia coli, GI2367259, Length=474, Percent_Identity=31.8565400843882, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI87082310, Length=443, Percent_Identity=31.6027088036117, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI2367379, Length=316, Percent_Identity=23.7341772151899, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI2367193, Length=450, Percent_Identity=22.2222222222222, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=397, Percent_Identity=23.9294710327456, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564204, Length=397, Percent_Identity=23.9294710327456, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17542316, Length=448, Percent_Identity=20.9821428571429, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI133901854, Length=434, Percent_Identity=21.889400921659, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI133901856, Length=437, Percent_Identity=20.5949656750572, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50861; Mature: 50861

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLLKKGPSANKVPAEKIQATYGRYRMQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHC
LSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSTAFWVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAIL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
GTEHWQSASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAP
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCC
ENMSAFQIFCTYVLRNKNAWYVSFVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFL
CCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FFEWAAIPSTLLAGWLSDKLFKGRRMPLAIICMTLIFICLIGYWKSESLLMVTVFAAIVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LLMGGIVCCILFCYLSHRGALELEQQRKNTEQEEARLALANAQ
HHHHHHHHHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MLSLLKKGPSANKVPAEKIQATYGRYRMQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHC
LSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVNVGLGFSTAFWVF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AALVVLNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNVGGGIVAPIVGAAFAIL
HHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
GTEHWQSASYIVPACVAVVFAISVLVLGKGSPREEGLPSLAEMMPEEKVVLKTKHGQKAP
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCC
ENMSAFQIFCTYVLRNKNAWYVSFVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFL
CCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
FFEWAAIPSTLLAGWLSDKLFKGRRMPLAIICMTLIFICLIGYWKSESLLMVTVFAAIVG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKMGWHGGFY
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LLMGGIVCCILFCYLSHRGALELEQQRKNTEQEEARLALANAQ
HHHHHHHHHHHHHHHCCCCCEEHHHHHCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 3042749 [H]