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The map label for this gene is pgtB [H]

Identifier: 238894757

GI number: 238894757

Start: 2637770

End: 2639779

Strand: Reverse

Name: pgtB [H]

Synonym: KP1_2765

Alternate gene names: 238894757

Gene position: 2639779-2637770 (Counterclockwise)

Preceding gene: 238894758

Following gene: 238894756

Centisome position: 50.3

GC content: 56.57

Gene sequence:

>2010_bases
ATGACGGACAGGTCCATGCTGCAACGCCTGCGGCAAATCAGTATCAGTAGCAGTCTGCGCGGGGCATTTCTGACGGGGGC
GCTGCTTACGCTGATTGTCAGCAGCGTAAGCCTCTATTCCTGGCATGAACAAAGTTCGCAGATCCGCTATTCGCTGGATG
AGTATTTTCCGCGCATCCATGCGGCTTTTCTGATTGAAGGGAATCTCAACCTGGTGGTCGATCAGCTCAATGAATTTCTG
CTGGCGCCAAATACCACGGTACGACTGCAGCTGCGCAACCAGATTATCCAGCATCTGGACAAAATAGAACGGCTAAGTCA
GGGGTTGTCGCCGGCAGAACGCCAGCAGTTGGGGGTGATATTGCAGGACAGCCGCGCGCTGCTGGCGGAACTGGATCGCG
TGCTCTACAACATGTTTCTGGTTCGTGAAAAGGTGGGAGAGCTTGCGGCGCGGATCGACTGGCTGCACGATGATTTCACC
ACCGAGCTAAATTCGCTGGTGCAGGATTTTACCTGGCAACAGGGAACGCTGCTCGATCAGATTGAAGCCCGACAGGGGGA
TGCGAGGCAGTATCTGAAACGCGCCCGGGAAGTGCAGAATGAACAGCAGCAGGTCTATACCCTGGCTCGTATTGAAAATC
AGATCGTTGACGACCTGCGCGACAGGCTCAATGAACTGAAATCCGGGAATGATGACGGCATGCTGGTGGAGACGCATATC
CGCTATCTTGAAAACCTGAAAAAAACGGCGGATGAAAATATCCGTGCGCTGGATGACTGGCCGAGCACCATTACCCTGCG
ACAAACGATAGATGAGCTGCTGGAAATTGGCATGGTGAAAAATAATATGCCGGATACCATGCGCGACTATGTTAGCGCGC
AAAAAGCGCTCGTGGAAGCCAGCCGGTCCAGAGAAGCGACGCTGGGGCGCTTCAGAACGCTGCTGGAAGCCCAGCTTGGC
AGCAGTCACCAGCAGATGCAGATGTTTAATCAGCGTATGGCGCAGATTGTCCGGGTCAGCGGCGGGTTAATCCTGGTGGC
GACCTTGCTGGCGCTGCTGCTGGCATGGGGGCTAAACCATTATTTTATTCGCTCGCGGCTGGTGAAACGCTTTACCGCGC
TGAATCAGGCGGTGGTGCAGATTGGTCTGGGCCGGACCGAGGCGACCATTCCGGTTTACGGGCGCGACGAGCTGGGACGT
ATTGCCGGTTTGCTTCGTCATACCCTGGGTCAGCTTAATGCGCAAAAACAGCAGCTGGAACAGGAGATTGGCGAGCGAAA
AGCGATTGAGGCCGATCTGCGCGCCACGCAGGACGAGCTGATCCAGACCGCTAAACTGGCGGTGGTGGGGCAGACGATGA
CCACCCTGGCGCATGAGATTAATCAGCCGCTGAACGCGCTGTCGATGTATCTTTTTACGGCGGGAAGGGCGATCGAACAG
GGACAGGCGGAGCAGGCGCGGACGACGTTAAGCAAAGCAGAAGGGCTGATCAACCGCATTGACGCGATTATCCGCTCCCT
GCGCCAGTTTACCCGCCGCGCAGAACTGGAAACGCCGCTGCATCCGGTCGATTTGCGTCAGACGTTTACCGTGGCGTGGG
AACTGCTGGCGATGCGTCATAAGCCTCAGCAGGGGACGCTGGTGATACCGGATGACACTGTCTGGATCCAGGGGGACGAA
GTGCGCGTCCATCAGGTGCTGGTGAACGTGCTGTCCAATGCCCTCGACGCCTGCCCGCACGCCGCGCAAATCACCGTGAG
CTGGCAAATCCAGGGCGGAAGGCTGTGCGTGTTGATTGCCGATAACGGCCCTGGCTGGCCTGCGGCCTTACTCCCTTCGC
TGTTAAAGCCGTTCACTACCAGTAAAACCGTGGGGCTCGGAATAGGGCTTTCGATATGTGTTTCGCTGATGACGCAAATG
GAAGGGGCGTTGCGCCTGGCGTCGACGTTTACACGCAGTGCCTGCGTGGTGCTGGAATTCAATTTGACGGATGTAAAAGA
TGTTGAGTAA

Upstream 100 bases:

>100_bases
AGTTCGACAACAAAAGTTTTGCGGAACAGCAGATGATGGAGTGGCAGCTCTGGTTTCTCAACAACCAGCGGCAGGCGATT
ACTAAACTGGAAGAACTGAA

Downstream 100 bases:

>100_bases
TAACTGTTCGATTCTGCTGATTGACGATGATGCCGATGTGCTGGATGCCTATACGCAGCTGCTTGAGCAAGCGGGGTATC
ATGTCAGTGCCTGTAATAAT

Product: phosphoglycerate transport system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MTDRSMLQRLRQISISSSLRGAFLTGALLTLIVSSVSLYSWHEQSSQIRYSLDEYFPRIHAAFLIEGNLNLVVDQLNEFL
LAPNTTVRLQLRNQIIQHLDKIERLSQGLSPAERQQLGVILQDSRALLAELDRVLYNMFLVREKVGELAARIDWLHDDFT
TELNSLVQDFTWQQGTLLDQIEARQGDARQYLKRAREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNDDGMLVETHI
RYLENLKKTADENIRALDDWPSTITLRQTIDELLEIGMVKNNMPDTMRDYVSAQKALVEASRSREATLGRFRTLLEAQLG
SSHQQMQMFNQRMAQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTEATIPVYGRDELGR
IAGLLRHTLGQLNAQKQQLEQEIGERKAIEADLRATQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQ
GQAEQARTTLSKAEGLINRIDAIIRSLRQFTRRAELETPLHPVDLRQTFTVAWELLAMRHKPQQGTLVIPDDTVWIQGDE
VRVHQVLVNVLSNALDACPHAAQITVSWQIQGGRLCVLIADNGPGWPAALLPSLLKPFTTSKTVGLGIGLSICVSLMTQM
EGALRLASTFTRSACVVLEFNLTDVKDVE

Sequences:

>Translated_669_residues
MTDRSMLQRLRQISISSSLRGAFLTGALLTLIVSSVSLYSWHEQSSQIRYSLDEYFPRIHAAFLIEGNLNLVVDQLNEFL
LAPNTTVRLQLRNQIIQHLDKIERLSQGLSPAERQQLGVILQDSRALLAELDRVLYNMFLVREKVGELAARIDWLHDDFT
TELNSLVQDFTWQQGTLLDQIEARQGDARQYLKRAREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNDDGMLVETHI
RYLENLKKTADENIRALDDWPSTITLRQTIDELLEIGMVKNNMPDTMRDYVSAQKALVEASRSREATLGRFRTLLEAQLG
SSHQQMQMFNQRMAQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTEATIPVYGRDELGR
IAGLLRHTLGQLNAQKQQLEQEIGERKAIEADLRATQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQ
GQAEQARTTLSKAEGLINRIDAIIRSLRQFTRRAELETPLHPVDLRQTFTVAWELLAMRHKPQQGTLVIPDDTVWIQGDE
VRVHQVLVNVLSNALDACPHAAQITVSWQIQGGRLCVLIADNGPGWPAALLPSLLKPFTTSKTVGLGIGLSICVSLMTQM
EGALRLASTFTRSACVVLEFNLTDVKDVE
>Mature_668_residues
TDRSMLQRLRQISISSSLRGAFLTGALLTLIVSSVSLYSWHEQSSQIRYSLDEYFPRIHAAFLIEGNLNLVVDQLNEFLL
APNTTVRLQLRNQIIQHLDKIERLSQGLSPAERQQLGVILQDSRALLAELDRVLYNMFLVREKVGELAARIDWLHDDFTT
ELNSLVQDFTWQQGTLLDQIEARQGDARQYLKRAREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNDDGMLVETHIR
YLENLKKTADENIRALDDWPSTITLRQTIDELLEIGMVKNNMPDTMRDYVSAQKALVEASRSREATLGRFRTLLEAQLGS
SHQQMQMFNQRMAQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTEATIPVYGRDELGRI
AGLLRHTLGQLNAQKQQLEQEIGERKAIEADLRATQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQG
QAEQARTTLSKAEGLINRIDAIIRSLRQFTRRAELETPLHPVDLRQTFTVAWELLAMRHKPQQGTLVIPDDTVWIQGDEV
RVHQVLVNVLSNALDACPHAAQITVSWQIQGGRLCVLIADNGPGWPAALLPSLLKPFTTSKTVGLGIGLSICVSLMTQME
GALRLASTFTRSACVVLEFNLTDVKDVE

Specific function: Member of the two-component regulatory system pgtB/pgtA that regulates the inducible phosphoglycerate transport system. Activates pgtA by phosphorylation [H]

COG id: COG4192

COG function: function code T; Signal transduction histidine kinase regulating phosphoglycerate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=28, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=26.2948207171315, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=279, Percent_Identity=26.1648745519713, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017116 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75383; Mature: 75252

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRSMLQRLRQISISSSLRGAFLTGALLTLIVSSVSLYSWHEQSSQIRYSLDEYFPRIH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFLIEGNLNLVVDQLNEFLLAPNTTVRLQLRNQIIQHLDKIERLSQGLSPAERQQLGVI
EEEEEECCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHH
LQDSRALLAELDRVLYNMFLVREKVGELAARIDWLHDDFTTELNSLVQDFTWQQGTLLDQ
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IEARQGDARQYLKRAREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNDDGMLVETHI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHH
RYLENLKKTADENIRALDDWPSTITLRQTIDELLEIGMVKNNMPDTMRDYVSAQKALVEA
HHHHHHHHHHCCCCEECCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SRSREATLGRFRTLLEAQLGSSHQQMQMFNQRMAQIVRVSGGLILVATLLALLLAWGLNH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
YFIRSRLVKRFTALNQAVVQIGLGRTEATIPVYGRDELGRIAGLLRHTLGQLNAQKQQLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
QEIGERKAIEADLRATQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHC
GQAEQARTTLSKAEGLINRIDAIIRSLRQFTRRAELETPLHPVDLRQTFTVAWELLAMRH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
KPQQGTLVIPDDTVWIQGDEVRVHQVLVNVLSNALDACPHAAQITVSWQIQGGRLCVLIA
CCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEEE
DNGPGWPAALLPSLLKPFTTSKTVGLGIGLSICVSLMTQMEGALRLASTFTRSACVVLEF
CCCCCCHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
NLTDVKDVE
CCCCCCCCC
>Mature Secondary Structure 
TDRSMLQRLRQISISSSLRGAFLTGALLTLIVSSVSLYSWHEQSSQIRYSLDEYFPRIH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAFLIEGNLNLVVDQLNEFLLAPNTTVRLQLRNQIIQHLDKIERLSQGLSPAERQQLGVI
EEEEEECCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHH
LQDSRALLAELDRVLYNMFLVREKVGELAARIDWLHDDFTTELNSLVQDFTWQQGTLLDQ
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
IEARQGDARQYLKRAREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNDDGMLVETHI
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHH
RYLENLKKTADENIRALDDWPSTITLRQTIDELLEIGMVKNNMPDTMRDYVSAQKALVEA
HHHHHHHHHHCCCCEECCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SRSREATLGRFRTLLEAQLGSSHQQMQMFNQRMAQIVRVSGGLILVATLLALLLAWGLNH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHH
YFIRSRLVKRFTALNQAVVQIGLGRTEATIPVYGRDELGRIAGLLRHTLGQLNAQKQQLE
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
QEIGERKAIEADLRATQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCHHHHC
GQAEQARTTLSKAEGLINRIDAIIRSLRQFTRRAELETPLHPVDLRQTFTVAWELLAMRH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
KPQQGTLVIPDDTVWIQGDEVRVHQVLVNVLSNALDACPHAAQITVSWQIQGGRLCVLIA
CCCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEEEE
DNGPGWPAALLPSLLKPFTTSKTVGLGIGLSICVSLMTQMEGALRLASTFTRSACVVLEF
CCCCCCHHHHHHHHHCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEE
NLTDVKDVE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2842311; 11677609; 2842312 [H]