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The map label for this gene is exuT [H]

Identifier: 238894735

GI number: 238894735

Start: 2616728

End: 2618098

Strand: Reverse

Name: exuT [H]

Synonym: KP1_2742

Alternate gene names: 238894735

Gene position: 2618098-2616728 (Counterclockwise)

Preceding gene: 238894736

Following gene: 238894734

Centisome position: 49.88

GC content: 57.99

Gene sequence:

>1371_bases
ATGCTGTCGCGACGCCGCGGAGTAAACACGACTATGACAACAATCAATCACACACCTGCCGGTGAACAACGTGGCAAAAA
GCGGCTGATACATCGCTTCTCCTGGGTTTCGCTACTGGTTTGCTGGCTAATCTGGGTGCTTAACGCCTACGATCGCGAGA
TGATCCTGCGCCTTGGCCCGGTCATCTCTAAGGAGTTCTCGCTCTCGCCGGAACAGTGGGGCAATATCGTCGCCCTGATC
ATGGTAGCCCTTGCGGTGCTGGATATTCCCGGCTCCATCTGGAGCGATCGCTACGGGTCTGGCTGGAAACGAGCGCGCTT
TCAGGTACCGCTGGTGCTGGGCTATACCGCGCTGTCTTTTATTTCCGGGATTAAAGCGATCAGCCACGGGCTGACGGCCT
TTGTGCTGCTGCGCGTGGGCGTCAACCTTGGGGCCGGCTGGGGCGAACCCGTCGGCGTCAGCAACACCGCGGAGTGGTGG
CCGAAAGAGAAGCGTGGTTTTGCGCTGGGGGTGCATCATACCGGCTATCCGATTGGCGCGCTGCTGAGCGGCGTGGTGGC
AAGCCTGGTGCTTGCCACGTTTGGCGAAGGCAGCTGGCGCTACTGCTTCCTGCTGGCGCTGCTCGTCGCCATCCCGCTAA
TGATCTTCTGGGCAAAATATTCTACCGCCGACCGCATCAACACGCTTTATCAGCATATCGACAGCCAGGGGTTGACGCGC
CCGGCGACGCAGGAAAGCAGCCATGTCGCCAAAGGCGAAGGGATGAAGACCTTTTTACGCACCCTGCGCAACCGCAATAT
TTCGCTGACGGCGGGCAATACCCTGCTGACGCAAATCGTCTATATGGGCATTAACGTTGTACTGCCCCCGTATCTTTATC
ACGTCTCCGGCCTGTCGCTGGCGGCGTCCGCCGGGCTGAGTATTATCTTCACGCTTACCGGTACCCTGGGTCAGGTAATC
TGGCCCTGGCTGTCGGATAGCTTTGGCCGTAAACGAACCCTGATCGTCTGCGGTCTGTGGATGAGTATCGGCATTGCGCT
GTTCTATTTCGCCACCAATATGCCGCGCCTTATCGCCATTCAGCTATTTTTTGGCCTGGTGGCCAACGCCGTGTGGCCTA
TCTACTACGCCATGGCGTCGGACTCCGCCGAAGAACGCGCCACCTCTACCGCTAACGGAATCATCACCACGGCGATGTTT
ATCGGCGGCGGCATTTCGCCATTGCTTATGGGCTGGCTCATTCAGTTTGGCGGCGGCTGGGAAAATCCAGCGGGTTATAT
CTACGCCTTCTTTACCATGGCGGGATGTGCGCTGCTGGGGATGTTATTACAGCTCATGACCACCGATAAAACGCCGCGCA
AAGCGCATTAA

Upstream 100 bases:

>100_bases
GCGGAACGGCGCTTCGCCGGCTAAACGAACCACCGGCTCGCCGCGATAACAATAATACCCGGCGAACTGACTCTGACCCT
GACACCAGGCGGCGCGCATC

Downstream 100 bases:

>100_bases
CGCAGGAGAACGTATGAAGATTGTTATCGCGCTGGATTCGTTTAAAGGTAGCTGTAGCGCGCAGGCCGCTTGCGCAGCGG
TAGCCCAGGGATTGCGCCGG

Product: putative general substrate transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLSRRRGVNTTMTTINHTPAGEQRGKKRLIHRFSWVSLLVCWLIWVLNAYDREMILRLGPVISKEFSLSPEQWGNIVALI
MVALAVLDIPGSIWSDRYGSGWKRARFQVPLVLGYTALSFISGIKAISHGLTAFVLLRVGVNLGAGWGEPVGVSNTAEWW
PKEKRGFALGVHHTGYPIGALLSGVVASLVLATFGEGSWRYCFLLALLVAIPLMIFWAKYSTADRINTLYQHIDSQGLTR
PATQESSHVAKGEGMKTFLRTLRNRNISLTAGNTLLTQIVYMGINVVLPPYLYHVSGLSLAASAGLSIIFTLTGTLGQVI
WPWLSDSFGRKRTLIVCGLWMSIGIALFYFATNMPRLIAIQLFFGLVANAVWPIYYAMASDSAEERATSTANGIITTAMF
IGGGISPLLMGWLIQFGGGWENPAGYIYAFFTMAGCALLGMLLQLMTTDKTPRKAH

Sequences:

>Translated_456_residues
MLSRRRGVNTTMTTINHTPAGEQRGKKRLIHRFSWVSLLVCWLIWVLNAYDREMILRLGPVISKEFSLSPEQWGNIVALI
MVALAVLDIPGSIWSDRYGSGWKRARFQVPLVLGYTALSFISGIKAISHGLTAFVLLRVGVNLGAGWGEPVGVSNTAEWW
PKEKRGFALGVHHTGYPIGALLSGVVASLVLATFGEGSWRYCFLLALLVAIPLMIFWAKYSTADRINTLYQHIDSQGLTR
PATQESSHVAKGEGMKTFLRTLRNRNISLTAGNTLLTQIVYMGINVVLPPYLYHVSGLSLAASAGLSIIFTLTGTLGQVI
WPWLSDSFGRKRTLIVCGLWMSIGIALFYFATNMPRLIAIQLFFGLVANAVWPIYYAMASDSAEERATSTANGIITTAMF
IGGGISPLLMGWLIQFGGGWENPAGYIYAFFTMAGCALLGMLLQLMTTDKTPRKAH
>Mature_456_residues
MLSRRRGVNTTMTTINHTPAGEQRGKKRLIHRFSWVSLLVCWLIWVLNAYDREMILRLGPVISKEFSLSPEQWGNIVALI
MVALAVLDIPGSIWSDRYGSGWKRARFQVPLVLGYTALSFISGIKAISHGLTAFVLLRVGVNLGAGWGEPVGVSNTAEWW
PKEKRGFALGVHHTGYPIGALLSGVVASLVLATFGEGSWRYCFLLALLVAIPLMIFWAKYSTADRINTLYQHIDSQGLTR
PATQESSHVAKGEGMKTFLRTLRNRNISLTAGNTLLTQIVYMGINVVLPPYLYHVSGLSLAASAGLSIIFTLTGTLGQVI
WPWLSDSFGRKRTLIVCGLWMSIGIALFYFATNMPRLIAIQLFFGLVANAVWPIYYAMASDSAEERATSTANGIITTAMF
IGGGISPLLMGWLIQFGGGWENPAGYIYAFFTMAGCALLGMLLQLMTTDKTPRKAH

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI2367379, Length=420, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082320, Length=448, Percent_Identity=21.4285714285714, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI2367193, Length=448, Percent_Identity=21.4285714285714, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50089; Mature: 50089

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRRRGVNTTMTTINHTPAGEQRGKKRLIHRFSWVSLLVCWLIWVLNAYDREMILRLGP
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VISKEFSLSPEQWGNIVALIMVALAVLDIPGSIWSDRYGSGWKRARFQVPLVLGYTALSF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHCEEECHHHHHHHHHHH
ISGIKAISHGLTAFVLLRVGVNLGAGWGEPVGVSNTAEWWPKEKRGFALGVHHTGYPIGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCHHH
LLSGVVASLVLATFGEGSWRYCFLLALLVAIPLMIFWAKYSTADRINTLYQHIDSQGLTR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
PATQESSHVAKGEGMKTFLRTLRNRNISLTAGNTLLTQIVYMGINVVLPPYLYHVSGLSL
CCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHCCHHH
AASAGLSIIFTLTGTLGQVIWPWLSDSFGRKRTLIVCGLWMSIGIALFYFATNMPRLIAI
HHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCHHHHHH
QLFFGLVANAVWPIYYAMASDSAEERATSTANGIITTAMFIGGGISPLLMGWLIQFGGGW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ENPAGYIYAFFTMAGCALLGMLLQLMTTDKTPRKAH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLSRRRGVNTTMTTINHTPAGEQRGKKRLIHRFSWVSLLVCWLIWVLNAYDREMILRLGP
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VISKEFSLSPEQWGNIVALIMVALAVLDIPGSIWSDRYGSGWKRARFQVPLVLGYTALSF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHCEEECHHHHHHHHHHH
ISGIKAISHGLTAFVLLRVGVNLGAGWGEPVGVSNTAEWWPKEKRGFALGVHHTGYPIGA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEECCCCCCHHH
LLSGVVASLVLATFGEGSWRYCFLLALLVAIPLMIFWAKYSTADRINTLYQHIDSQGLTR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
PATQESSHVAKGEGMKTFLRTLRNRNISLTAGNTLLTQIVYMGINVVLPPYLYHVSGLSL
CCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHCCHHHHHHCCHHH
AASAGLSIIFTLTGTLGQVIWPWLSDSFGRKRTLIVCGLWMSIGIALFYFATNMPRLIAI
HHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCHHHHHH
QLFFGLVANAVWPIYYAMASDSAEERATSTANGIITTAMFIGGGISPLLMGWLIQFGGGW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ENPAGYIYAFFTMAGCALLGMLLQLMTTDKTPRKAH
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]