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The map label for this gene is sotB [H]

Identifier: 238894658

GI number: 238894658

Start: 2547409

End: 2548608

Strand: Reverse

Name: sotB [H]

Synonym: KP1_2663

Alternate gene names: 238894658

Gene position: 2548608-2547409 (Counterclockwise)

Preceding gene: 238894660

Following gene: 238894655

Centisome position: 48.56

GC content: 60.58

Gene sequence:

>1200_bases
ATGACTACGAATACGGTCTCACGCAAGGTAGCGTGGCTACGTGTCGTGACGTTGGCCATCGCCGCGTTTATTTTTAACAC
CACAGAGTTTGCCCCGGTCGGTCTGTTGTCGGATATTGCCGACAGCTTCGGCATGGAAACCGCCCAGGTGGGCATGATGC
TGACCATCTACGCATGGGTGGTGGCGTTAATGTCGCTGCCGTTTATGCTGCTAACCAGCAAAGTGGAGCGCCGGCGCCTG
CTTATCGGCCTGTTTATTCTGTTTATCGCCAGCCACGTCCTGTCGTTTTTTGCCTGGAATTTTGACGTGCTGGTGATTAG
CCGCATTGGCATCGCCTTTGCGCATGCGGTTTTCTGGTCGATAACGTCGGCACTGGCCATCCGCATGGCCCCGCCGGGCA
AACGGGCGCAGGCGCTGAGCCTGATCGCCACCGGTACCGCGCTGGCGATGGTGTTTGGTATTCCGATCGGGCGCATTATC
GGCCAGTACTTTGGCTGGCGGATGACCTTCCTGGCGATCGGCCTCGGCGCGTTAGCCACCCTGGCCTGCCTCGTAAAACT
GCTGCCGACCCTGCCGAGCGAACATTCTGGCTCGCTGAAAAGCCTGCCGGTGCTGTTCCGCCGCCCGGCGCTGGTCAGCG
TGTACATTCTGACCGTGGTGGTGGTGACCGCTCATTATACCGCCTACAGCTATATCGAGCCCTTTGTCCAGACGGTAGCG
GGCCTGAGCGGCAACTTTGCCACCGTACTGCTGCTGATCCTTGGCGGGGCCGGTATTATCGGCAGCATTCTGTTCGGTAA
GCTCGGTAACCAGCACGCGTCGGGGCTGATAAGCCTGGCGATTGCCCTGCTGCTCGCCTGCCTGCTGCTGCTGCTGCCGG
CCTCGCATAACCCGCAGCACCTGATGCTGCTCAGCATCTTCTGGGGGGTGGCGATCATGATTATCGGTCTCGGCATGCAG
GTGAAAGTGCTGGCCTCCGCTCCGGATGCCACCGACGTCGCCATGTCTCTGTTCTCGGGCATCTTTAATATCGGCATAGG
CGCCGGGGCGCTGGTCGGCAGCCAGGTGAGTCTGCATCTTTCCATGGCCTCCGTCGGCTACGTCGGCGCCATTCCGGCGC
TGGTCGCGCTGGTCTGGTCGCTGATGATATTCCGTCGCTGGCCGGTATCGCTGGAAGACCATCAGCCGCACCACTCCTGA

Upstream 100 bases:

>100_bases
GCGATGAAATGAGACGCAGATCACAAAATGATTGTCTTTTCGCCAACAATCGTTTTAAGATCAGCGTCACATCTTTCCCT
GAATCACCAGTCCAGAGCTT

Downstream 100 bases:

>100_bases
TTCCGTCGCACAAAAAAGCCCGCCGGTATCGCGCCGGCGGGCTTTTTTTCTCTGCGCATCGCGGGCGGTCAGGGATGCCA
GGTCGAAATGATCTCCAGCA

Product: sugar efflux transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MTTNTVSRKVAWLRVVTLAIAAFIFNTTEFAPVGLLSDIADSFGMETAQVGMMLTIYAWVVALMSLPFMLLTSKVERRRL
LIGLFILFIASHVLSFFAWNFDVLVISRIGIAFAHAVFWSITSALAIRMAPPGKRAQALSLIATGTALAMVFGIPIGRII
GQYFGWRMTFLAIGLGALATLACLVKLLPTLPSEHSGSLKSLPVLFRRPALVSVYILTVVVVTAHYTAYSYIEPFVQTVA
GLSGNFATVLLLILGGAGIIGSILFGKLGNQHASGLISLAIALLLACLLLLLPASHNPQHLMLLSIFWGVAIMIIGLGMQ
VKVLASAPDATDVAMSLFSGIFNIGIGAGALVGSQVSLHLSMASVGYVGAIPALVALVWSLMIFRRWPVSLEDHQPHHS

Sequences:

>Translated_399_residues
MTTNTVSRKVAWLRVVTLAIAAFIFNTTEFAPVGLLSDIADSFGMETAQVGMMLTIYAWVVALMSLPFMLLTSKVERRRL
LIGLFILFIASHVLSFFAWNFDVLVISRIGIAFAHAVFWSITSALAIRMAPPGKRAQALSLIATGTALAMVFGIPIGRII
GQYFGWRMTFLAIGLGALATLACLVKLLPTLPSEHSGSLKSLPVLFRRPALVSVYILTVVVVTAHYTAYSYIEPFVQTVA
GLSGNFATVLLLILGGAGIIGSILFGKLGNQHASGLISLAIALLLACLLLLLPASHNPQHLMLLSIFWGVAIMIIGLGMQ
VKVLASAPDATDVAMSLFSGIFNIGIGAGALVGSQVSLHLSMASVGYVGAIPALVALVWSLMIFRRWPVSLEDHQPHHS
>Mature_398_residues
TTNTVSRKVAWLRVVTLAIAAFIFNTTEFAPVGLLSDIADSFGMETAQVGMMLTIYAWVVALMSLPFMLLTSKVERRRLL
IGLFILFIASHVLSFFAWNFDVLVISRIGIAFAHAVFWSITSALAIRMAPPGKRAQALSLIATGTALAMVFGIPIGRIIG
QYFGWRMTFLAIGLGALATLACLVKLLPTLPSEHSGSLKSLPVLFRRPALVSVYILTVVVVTAHYTAYSYIEPFVQTVAG
LSGNFATVLLLILGGAGIIGSILFGKLGNQHASGLISLAIALLLACLLLLLPASHNPQHLMLLSIFWGVAIMIIGLGMQV
KVLASAPDATDVAMSLFSGIFNIGIGAGALVGSQVSLHLSMASVGYVGAIPALVALVWSLMIFRRWPVSLEDHQPHHS

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=394, Percent_Identity=81.2182741116751, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI1787947, Length=379, Percent_Identity=34.0369393139842, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI145693198, Length=347, Percent_Identity=27.6657060518732, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786595, Length=386, Percent_Identity=23.8341968911917, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42610; Mature: 42479

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTNTVSRKVAWLRVVTLAIAAFIFNTTEFAPVGLLSDIADSFGMETAQVGMMLTIYAWV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VALMSLPFMLLTSKVERRRLLIGLFILFIASHVLSFFAWNFDVLVISRIGIAFAHAVFWS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
ITSALAIRMAPPGKRAQALSLIATGTALAMVFGIPIGRIIGQYFGWRMTFLAIGLGALAT
HHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LACLVKLLPTLPSEHSGSLKSLPVLFRRPALVSVYILTVVVVTAHYTAYSYIEPFVQTVA
HHHHHHHHHCCCCCCCCCCHHCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSGNFATVLLLILGGAGIIGSILFGKLGNQHASGLISLAIALLLACLLLLLPASHNPQH
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
LMLLSIFWGVAIMIIGLGMQVKVLASAPDATDVAMSLFSGIFNIGIGAGALVGSQVSLHL
HHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHCCHHEEEE
SMASVGYVGAIPALVALVWSLMIFRRWPVSLEDHQPHHS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA