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The map label for this gene is ygbJ [H]

Identifier: 238894631

GI number: 238894631

Start: 2522673

End: 2523575

Strand: Reverse

Name: ygbJ [H]

Synonym: KP1_2632

Alternate gene names: 238894631

Gene position: 2523575-2522673 (Counterclockwise)

Preceding gene: 238894633

Following gene: 238894630

Centisome position: 48.08

GC content: 64.23

Gene sequence:

>903_bases
ATGGCTGCACACACTAACGTCTGCGTGATTGGACTGGGTTCAATGGGCATGGGCGCTGCCCGCGCCTGCCTGCAGGCGGG
CCTGAACACCTGGGGCGTTGACATCAATCCCGACAACTGTCGCGCACTGCTGGCGGCGGGCGCCAAAGGCGCGGGCCCCA
GCGCGGTGCCGTTCGCCGCGGAACTGGATGCAGTTGTGCTGCTGGTGGTCAATGCCGCCCAGGTGCGGGGGATCCTGTTC
GGCGAGAGCGGCCTCGCCGCCCATCTGAAGCCGGGCACCGTCGTGATGGTGTCGTCCACCATCGCCTCCGCCGATGCTCA
GGCCATTGCCGAGGCGCTGGCGGAGTACCAGCTATTGATGCTCGACGCGCCGGTATCGGGCGGCGCCGTGAAAGCGGCCG
CCGGCGACATGACGGTGATGGCCTCCGGGAGCGATGCCGCCTTTGCCCGCCTCGCGCCGGTGCTGGACGCCGTGGCCGGC
AAAGTCTACCGCATCGGGAGCGACATTGGTCTTGGCTCGACGGTAAAAATTATCCATCAGCTGCTGGCCGGGGTGCACAT
CGCCGTTGCCGCCGAAGCGATGGCGCTTGCCGCCCGCGCCGGGATCCCACTGGAGACGATGTATGACGTGGTCACCCACG
CGGCGGGTAATTCCTGGATGTTTGAGAATCGCATGCAGCACGTCCTGGATGGCGATTACTCGCCAAAATCCGCTGTCGAT
ATTTTTGTCAAAGATCTCGGGCTGGTGAATGACACTGCCCGGGCGCTGACCTTCCCGCTGCCGCTCGCTACCACCGCGCT
GAATATGTTCACCTCCGCCAGTAATGCCGGATTCGGTCGGGAAGATGACAGCGCGGTGATCAAGATTTTCAACGGCATCA
CCCTGCCGGGCCATAAACAGTGA

Upstream 100 bases:

>100_bases
ATGTGGGTTATTCGTGATAACTCTCACATAAATTCACATGATAACGCTTTATTCTATCATTAAATCACATTAATTAACTA
ATGTTCACAAGGAGACCAGC

Downstream 100 bases:

>100_bases
GGAGAGACAACATGCAGCTTGGTGTCATTGCCGATGACTTCACCGGCGCCACGGATATTGCCAGCTTCCTCGTGCGCAAC
GGCATGCCGACGGTGCAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAAHTNVCVIGLGSMGMGAARACLQAGLNTWGVDINPDNCRALLAAGAKGAGPSAVPFAAELDAVVLLVVNAAQVRGILF
GESGLAAHLKPGTVVMVSSTIASADAQAIAEALAEYQLLMLDAPVSGGAVKAAAGDMTVMASGSDAAFARLAPVLDAVAG
KVYRIGSDIGLGSTVKIIHQLLAGVHIAVAAEAMALAARAGIPLETMYDVVTHAAGNSWMFENRMQHVLDGDYSPKSAVD
IFVKDLGLVNDTARALTFPLPLATTALNMFTSASNAGFGREDDSAVIKIFNGITLPGHKQ

Sequences:

>Translated_300_residues
MAAHTNVCVIGLGSMGMGAARACLQAGLNTWGVDINPDNCRALLAAGAKGAGPSAVPFAAELDAVVLLVVNAAQVRGILF
GESGLAAHLKPGTVVMVSSTIASADAQAIAEALAEYQLLMLDAPVSGGAVKAAAGDMTVMASGSDAAFARLAPVLDAVAG
KVYRIGSDIGLGSTVKIIHQLLAGVHIAVAAEAMALAARAGIPLETMYDVVTHAAGNSWMFENRMQHVLDGDYSPKSAVD
IFVKDLGLVNDTARALTFPLPLATTALNMFTSASNAGFGREDDSAVIKIFNGITLPGHKQ
>Mature_299_residues
AAHTNVCVIGLGSMGMGAARACLQAGLNTWGVDINPDNCRALLAAGAKGAGPSAVPFAAELDAVVLLVVNAAQVRGILFG
ESGLAAHLKPGTVVMVSSTIASADAQAIAEALAEYQLLMLDAPVSGGAVKAAAGDMTVMASGSDAAFARLAPVLDAVAGK
VYRIGSDIGLGSTVKIIHQLLAGVHIAVAAEAMALAARAGIPLETMYDVVTHAAGNSWMFENRMQHVLDGDYSPKSAVDI
FVKDLGLVNDTARALTFPLPLATTALNMFTSASNAGFGREDDSAVIKIFNGITLPGHKQ

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI23308751, Length=298, Percent_Identity=26.8456375838926, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI40556376, Length=282, Percent_Identity=23.0496453900709, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1789092, Length=295, Percent_Identity=76.271186440678, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI145693186, Length=281, Percent_Identity=33.0960854092527, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1790315, Length=285, Percent_Identity=31.2280701754386, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786719, Length=280, Percent_Identity=28.9285714285714, Blast_Score=103, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17557316, Length=269, Percent_Identity=27.5092936802974, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655230, Length=292, Percent_Identity=26.7123287671233, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19922568, Length=292, Percent_Identity=26.7123287671233, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28574115, Length=282, Percent_Identity=26.241134751773, Blast_Score=83, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 30508; Mature: 30376

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAHTNVCVIGLGSMGMGAARACLQAGLNTWGVDINPDNCRALLAAGAKGAGPSAVPFAA
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHH
ELDAVVLLVVNAAQVRGILFGESGLAAHLKPGTVVMVSSTIASADAQAIAEALAEYQLLM
HHHHHHHHHHHHHHHEEEEECCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEE
LDAPVSGGAVKAAAGDMTVMASGSDAAFARLAPVLDAVAGKVYRIGSDIGLGSTVKIIHQ
EECCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHH
LLAGVHIAVAAEAMALAARAGIPLETMYDVVTHAAGNSWMFENRMQHVLDGDYSPKSAVD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHH
IFVKDLGLVNDTARALTFPLPLATTALNMFTSASNAGFGREDDSAVIKIFNGITLPGHKQ
HHHHHHCCCCCCHHHEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHEEEECCCCCCCCCC
>Mature Secondary Structure 
AAHTNVCVIGLGSMGMGAARACLQAGLNTWGVDINPDNCRALLAAGAKGAGPSAVPFAA
CCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHH
ELDAVVLLVVNAAQVRGILFGESGLAAHLKPGTVVMVSSTIASADAQAIAEALAEYQLLM
HHHHHHHHHHHHHHHEEEEECCCCCEEEECCCEEEEEECCHHHHHHHHHHHHHHHHEEEE
LDAPVSGGAVKAAAGDMTVMASGSDAAFARLAPVLDAVAGKVYRIGSDIGLGSTVKIIHQ
EECCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHH
LLAGVHIAVAAEAMALAARAGIPLETMYDVVTHAAGNSWMFENRMQHVLDGDYSPKSAVD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHH
IFVKDLGLVNDTARALTFPLPLATTALNMFTSASNAGFGREDDSAVIKIFNGITLPGHKQ
HHHHHHCCCCCCHHHEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]