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The map label for this gene is mdcB [H]

Identifier: 238894581

GI number: 238894581

Start: 2479691

End: 2480581

Strand: Reverse

Name: mdcB [H]

Synonym: KP1_2580

Alternate gene names: 238894581

Gene position: 2480581-2479691 (Counterclockwise)

Preceding gene: 238894582

Following gene: 238894580

Centisome position: 47.26

GC content: 68.57

Gene sequence:

>891_bases
GTGGTCCGACGGACTGTACAACCCACCGGCAAAATTCCGGAGCTGGTAATGAAAAATCTCTCCCCCCTGCACGCAGAAAG
CCGCGTCAGCTGGCTGGCGCATACCGCCAGCGCCTGTCTGATTGACGAAGCCCGTCTGAGCCCGAAACCGGGTCTGGTGG
ATAGCCGCGGCAACGGCGCGCATCAGGACCTGAATCTGGCGCTGATGGAGCGCTCCGCCCGCAGCCTGCAGCCGACCTTT
CACGCGCTGGCCGAGCAAAGCTGGCGTCGCCCGGCGGACATCGCCCTGCGCGAAACCGTCGGCCGCCTTGGCCGCGAAGG
CGAAGCGCAGATGATGCTGGCGACGGGTGGGGTTAACACCCACCGCGGCGCTATCTGGGCGCTAGGCCTGCTGGTCAGCG
CGGTGGCGATGTTGGGTGGAGAGGGTCAGTCACAGGCGATCGCCGACGCCGCCGCCGCCCTCGCCCGCCTGCCCGACGGC
TTCGCGCCGAAAAGCTTTAGTAAAGGGCTTCGCGCCAGCCGCCGCTGGCAGGTGCCAGGCGCCCGCGAGGAAGCGCAGTG
TGGTTTCCCGCATATCACCCGCCTGGCGCTGCCGCAACTGCAGCACAGCCGGGCGCGAGGCGCCAGTGAGCCGCAGGCGC
AGCTTGATGCGCTGATGGCCATCATGACCTCGCTGAGCGATACCTGCGTGCTGTCGCGCGCCGGTATGGCCGGGCTGCAG
GCCATGCAGCAAGGCGCTTGCGAGGTGCTGGCGGCTGGCGGTTGCGCCAGTTTCGCCGGGCGCGCCGCCCTGGCCCGCCT
GGACGCAATCATGCTGGCGCTAAACGCCTCGCCGGGAGGCGCCGCCGATCTCCTTGCCGCCACCCTGTTTCTCGACAGAG
TTGCCGGCTAA

Upstream 100 bases:

>100_bases
GTCAGAGCGGCAAAGTGGTCTACCCGGAAGATCTCGGGATTCGCCGCAGCGATGCCACCCGCTCCCTGCTGGCCGCCGGC
AGCGTCGCCGACCTGGTGGA

Downstream 100 bases:

>100_bases
CGCATTCAGAGGATGTTATGGAACAGATTACATTGTCATTTCCTGCCAGCCGCGCCCTGAGCGGCAGAGCGCTGGCAGGA
GTCGTGGGTTCAGGCGATAT

Product: triphosphoribosyl-dephospho-CoA transferase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MVRRTVQPTGKIPELVMKNLSPLHAESRVSWLAHTASACLIDEARLSPKPGLVDSRGNGAHQDLNLALMERSARSLQPTF
HALAEQSWRRPADIALRETVGRLGREGEAQMMLATGGVNTHRGAIWALGLLVSAVAMLGGEGQSQAIADAAAALARLPDG
FAPKSFSKGLRASRRWQVPGAREEAQCGFPHITRLALPQLQHSRARGASEPQAQLDALMAIMTSLSDTCVLSRAGMAGLQ
AMQQGACEVLAAGGCASFAGRAALARLDAIMLALNASPGGAADLLAATLFLDRVAG

Sequences:

>Translated_296_residues
MVRRTVQPTGKIPELVMKNLSPLHAESRVSWLAHTASACLIDEARLSPKPGLVDSRGNGAHQDLNLALMERSARSLQPTF
HALAEQSWRRPADIALRETVGRLGREGEAQMMLATGGVNTHRGAIWALGLLVSAVAMLGGEGQSQAIADAAAALARLPDG
FAPKSFSKGLRASRRWQVPGAREEAQCGFPHITRLALPQLQHSRARGASEPQAQLDALMAIMTSLSDTCVLSRAGMAGLQ
AMQQGACEVLAAGGCASFAGRAALARLDAIMLALNASPGGAADLLAATLFLDRVAG
>Mature_296_residues
MVRRTVQPTGKIPELVMKNLSPLHAESRVSWLAHTASACLIDEARLSPKPGLVDSRGNGAHQDLNLALMERSARSLQPTF
HALAEQSWRRPADIALRETVGRLGREGEAQMMLATGGVNTHRGAIWALGLLVSAVAMLGGEGQSQAIADAAAALARLPDG
FAPKSFSKGLRASRRWQVPGAREEAQCGFPHITRLALPQLQHSRARGASEPQAQLDALMAIMTSLSDTCVLSRAGMAGLQ
AMQQGACEVLAAGGCASFAGRAALARLDAIMLALNASPGGAADLLAATLFLDRVAG

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=265, Percent_Identity=33.9622641509434, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 31019; Mature: 31019

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRRTVQPTGKIPELVMKNLSPLHAESRVSWLAHTASACLIDEARLSPKPGLVDSRGNGA
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HQDLNLALMERSARSLQPTFHALAEQSWRRPADIALRETVGRLGREGEAQMMLATGGVNT
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCC
HRGAIWALGLLVSAVAMLGGEGQSQAIADAAAALARLPDGFAPKSFSKGLRASRRWQVPG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
AREEAQCGFPHITRLALPQLQHSRARGASEPQAQLDALMAIMTSLSDTCVLSRAGMAGLQ
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMQQGACEVLAAGGCASFAGRAALARLDAIMLALNASPGGAADLLAATLFLDRVAG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRRTVQPTGKIPELVMKNLSPLHAESRVSWLAHTASACLIDEARLSPKPGLVDSRGNGA
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HQDLNLALMERSARSLQPTFHALAEQSWRRPADIALRETVGRLGREGEAQMMLATGGVNT
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCC
HRGAIWALGLLVSAVAMLGGEGQSQAIADAAAALARLPDGFAPKSFSKGLRASRRWQVPG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCC
AREEAQCGFPHITRLALPQLQHSRARGASEPQAQLDALMAIMTSLSDTCVLSRAGMAGLQ
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMQQGACEVLAAGGCASFAGRAALARLDAIMLALNASPGGAADLLAATLFLDRVAG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9208947; 11052675 [H]