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The map label for this gene is accD [H]

Identifier: 238894579

GI number: 238894579

Start: 2478548

End: 2479396

Strand: Reverse

Name: accD [H]

Synonym: KP1_2578

Alternate gene names: 238894579

Gene position: 2479396-2478548 (Counterclockwise)

Preceding gene: 238894580

Following gene: 238894578

Centisome position: 47.24

GC content: 62.31

Gene sequence:

>849_bases
TTGAGGAGGCCGCTCATGCGTAACGATCGCAGCTTTATCGAACTGCGCGCTCGCGAACGCGCCCACGCCCTGCTGGACGA
CGGCAGCTACCGCGAACTGCTGGATCCGTTTGACGGTATTATGTCGCCGTGGCTCGGCGCCCAGGGCATCGTCCCGCAGT
CCGACGACGGTATGGTGGTCGCCAAAGGCACGATCAACGGCCAGCCTGCGGTGGTGATTGCCATCGAGGGCACCTTCCAG
GGAGGCAGTATGGGCGAAGTGTCCGGCGCCAAAATGGCCGCCGCGCTGGAGCTGGCGGCGGAAGATAACCGCAACGGTAT
CCCGACGCAGGCGGTGCTGTGCCTCGAAACCGGCGGCGTACGTCTGCAGGAGGCCAACCTCGGTCTGGCCGCCATCGCTG
ATATTCACGCGGCGATTGTCGATCTGCGCCGCTACACGCCGGTAGTCGGCATCATCGCCGGCACCGTCGGCTGCTTTGGC
GGTATGTCTATCGCCGCCGCGCTGTGCAGCTATCTCATTGTCACTCGTGAAGCCCGTCTCGGCCTCAACGGCCCGCAGGT
TATCGAGCAGGAAGCCGGCATTGAAGAGTACGACTCCCGCAACCGGCCGTTTATCTGGAGCATGACCGGCGGCGAAATTC
GCGCCGCCAGCGGACTGGTCGACGCGCTGGTTAACGATGGCGTTAACGCCGTTAAAACCGCAATGAATGAGGCGATCGCC
AAAGGCGTACCGGTACAGCACCGCAGCGACAACTATGACGATTATCTGCGTCGCTTGAGCCAGTTCGACACCCGCCAGCA
GGCGGATACCGCGCAGATTAAACAGCTTTTTGCCCGGGAGGATAAATAA

Upstream 100 bases:

>100_bases
GACAGGTTGAACCTGATCAACGGCCTGCCCGCCGGGCAGTTGATTATCCACGACTTCGGCGCCACGCCGGGCGTCGCCCG
TATTCGTATTGAACAGGTTT

Downstream 100 bases:

>100_bases
TGAGTCAGTTCCCAAACCGCGCCGCGCTGTGGCTGAACAAACTGGCGCCCGACGCGCCGCTGATGAGCGGCCTGTGCCCT
TCCGTCCAGGTGGCAGACGG

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MRRPLMRNDRSFIELRARERAHALLDDGSYRELLDPFDGIMSPWLGAQGIVPQSDDGMVVAKGTINGQPAVVIAIEGTFQ
GGSMGEVSGAKMAAALELAAEDNRNGIPTQAVLCLETGGVRLQEANLGLAAIADIHAAIVDLRRYTPVVGIIAGTVGCFG
GMSIAAALCSYLIVTREARLGLNGPQVIEQEAGIEEYDSRNRPFIWSMTGGEIRAASGLVDALVNDGVNAVKTAMNEAIA
KGVPVQHRSDNYDDYLRRLSQFDTRQQADTAQIKQLFAREDK

Sequences:

>Translated_282_residues
MRRPLMRNDRSFIELRARERAHALLDDGSYRELLDPFDGIMSPWLGAQGIVPQSDDGMVVAKGTINGQPAVVIAIEGTFQ
GGSMGEVSGAKMAAALELAAEDNRNGIPTQAVLCLETGGVRLQEANLGLAAIADIHAAIVDLRRYTPVVGIIAGTVGCFG
GMSIAAALCSYLIVTREARLGLNGPQVIEQEAGIEEYDSRNRPFIWSMTGGEIRAASGLVDALVNDGVNAVKTAMNEAIA
KGVPVQHRSDNYDDYLRRLSQFDTRQQADTAQIKQLFAREDK
>Mature_282_residues
MRRPLMRNDRSFIELRARERAHALLDDGSYRELLDPFDGIMSPWLGAQGIVPQSDDGMVVAKGTINGQPAVVIAIEGTFQ
GGSMGEVSGAKMAAALELAAEDNRNGIPTQAVLCLETGGVRLQEANLGLAAIADIHAAIVDLRRYTPVVGIIAGTVGCFG
GMSIAAALCSYLIVTREARLGLNGPQVIEQEAGIEEYDSRNRPFIWSMTGGEIRAASGLVDALVNDGVNAVKTAMNEAIA
KGVPVQHRSDNYDDYLRRLSQFDTRQQADTAQIKQLFAREDK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=191, Percent_Identity=36.1256544502618, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 30328; Mature: 30328

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPLMRNDRSFIELRARERAHALLDDGSYRELLDPFDGIMSPWLGAQGIVPQSDDGMVV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
AKGTINGQPAVVIAIEGTFQGGSMGEVSGAKMAAALELAAEDNRNGIPTQAVLCLETGGV
EECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCCE
RLQEANLGLAAIADIHAAIVDLRRYTPVVGIIAGTVGCFGGMSIAAALCSYLIVTREARL
EEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLNGPQVIEQEAGIEEYDSRNRPFIWSMTGGEIRAASGLVDALVNDGVNAVKTAMNEAIA
CCCCHHHHHHHCCCHHHCCCCCCEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHH
KGVPVQHRSDNYDDYLRRLSQFDTRQQADTAQIKQLFAREDK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRPLMRNDRSFIELRARERAHALLDDGSYRELLDPFDGIMSPWLGAQGIVPQSDDGMVV
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEE
AKGTINGQPAVVIAIEGTFQGGSMGEVSGAKMAAALELAAEDNRNGIPTQAVLCLETGGV
EECCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECCCE
RLQEANLGLAAIADIHAAIVDLRRYTPVVGIIAGTVGCFGGMSIAAALCSYLIVTREARL
EEEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLNGPQVIEQEAGIEEYDSRNRPFIWSMTGGEIRAASGLVDALVNDGVNAVKTAMNEAIA
CCCCHHHHHHHCCCHHHCCCCCCEEEEECCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHH
KGVPVQHRSDNYDDYLRRLSQFDTRQQADTAQIKQLFAREDK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA