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The map label for this gene is murQ [H]

Identifier: 238894572

GI number: 238894572

Start: 2471215

End: 2472135

Strand: Direct

Name: murQ [H]

Synonym: KP1_2570

Alternate gene names: 238894572

Gene position: 2471215-2472135 (Clockwise)

Preceding gene: 238894571

Following gene: 238894573

Centisome position: 47.08

GC content: 63.95

Gene sequence:

>921_bases
ATGAGCAGTTCGCTAACCGCGTCAATGCAGGCTCGTCGTCACCCGGAGACCACCCACATCGATCGCCTCGCCACCGCCGA
TATGCTGGCGATGCTGCATCAGGATGATAAGCAGATATCGGAGGCGGTCGGCGCCTGTCTGCCGGATATCGCCCGGCTGA
TTGATATCGCCACCGCGACGATAAGCCGGGGAGGGCGCCTGGTCATTATTGGCGCCGGCGCTTCGGGCCGGACGGCCATT
GAGGCGGTCAGCGACTATTCACCGGAAGGTAAACACGCGCTGGTGGGGCTGATTGCCGGTGGGCAGACGACGGCGATGGC
CGAGCGGGAGACTGCAGCGAATAATTATGACCTGGGCGCCTTTGAGCTGCAGTCGCTGGACTTCAGCAATCGCGATATGC
TGCTGGCGCTGACCGTCAGCGGCAAGACGCCATGGGTGTGGGGGGCGATGCGCCACGCCTGGTCGCTGGGCGCCCCGATA
GCGGTCATCACCCAGCAGCCGACCAGCGAGGCGGCGCAGCTGGCGGATATCATTATTGCTCCGCAGACCGGGCCGGAGGC
GGTGGCGGGGTTAGCCAATCCGAAGGCTCAGTTGGCCCAGAGGCAGATCGTCAATATGCTGACAACCGGACTCGCCATCC
GTGACGGTCGGGTGTACAGCAATTTGCGGGTGGACGTGCAGGCTGACAATTCGCACTGGGCGGAGCGGCAGATAGCGATT
GTGATGGCGGCCACCGATTGCACGCGCAGTGAAGCAAAGGCCGCCCTGGCCAGCTGTCATCAGCACTGCCGCACCGCGAT
CCTGATGCTGCTCAGCGGGCTTGACGCCTGGCACGCGCGGGAGCTGCTAACCAAACATCACGATCATCTGCGCCTCGCCC
TGCGTGAAGCCCAGCGTAGCGCTGTCACTCCCGCCCAGTAA

Upstream 100 bases:

>100_bases
AGTGGCGGCAGAGGTTAAATAGTCCTGATGAATATAAGGATATGCATCAGGCCGCTGATTTTGCCGAGATGCGCTTTTTC
TGTCGTAAATGGAGGTTGTT

Downstream 100 bases:

>100_bases
TCCCTTCTCTGCCAGGCGCGCGATGAGCATGCGCGCCTGGACTTTTGTAATTAAAGAAATTCTTAGCTTTTATTTTACCC
GGCAATAGATATTGAATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATATISRGGRLVIIGAGASGRTAI
EAVSDYSPEGKHALVGLIAGGQTTAMAERETAANNYDLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPI
AVITQQPTSEAAQLADIIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAERQIAI
VMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRSAVTPAQ

Sequences:

>Translated_306_residues
MSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATATISRGGRLVIIGAGASGRTAI
EAVSDYSPEGKHALVGLIAGGQTTAMAERETAANNYDLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPI
AVITQQPTSEAAQLADIIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAERQIAI
VMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRSAVTPAQ
>Mature_305_residues
SSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATATISRGGRLVIIGAGASGRTAIE
AVSDYSPEGKHALVGLIAGGQTTAMAERETAANNYDLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPIA
VITQQPTSEAAQLADIIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAERQIAIV
MAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRSAVTPAQ

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=281, Percent_Identity=38.0782918149466, Blast_Score=196, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR000408
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32754; Mature: 32623

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATAT
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISRGGRLVIIGAGASGRTAIEAVSDYSPEGKHALVGLIAGGQTTAMAERETAANNYDLGA
HCCCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCC
FELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPIAVITQQPTSEAAQLADIIIA
EEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEC
PQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAERQIAI
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEEEEEEECCCCCCCEEEEE
VMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRS
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
AVTPAQ
CCCCCC
>Mature Secondary Structure 
SSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATAT
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISRGGRLVIIGAGASGRTAIEAVSDYSPEGKHALVGLIAGGQTTAMAERETAANNYDLGA
HCCCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCCCCCC
FELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPIAVITQQPTSEAAQLADIIIA
EEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEC
PQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAERQIAI
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEEEEEEECCCCCCCEEEEE
VMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRS
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
AVTPAQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA