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The map label for this gene is tus [H]

Identifier: 238894533

GI number: 238894533

Start: 2431471

End: 2432403

Strand: Reverse

Name: tus [H]

Synonym: KP1_2527

Alternate gene names: 238894533

Gene position: 2432403-2431471 (Counterclockwise)

Preceding gene: 238894534

Following gene: 238894530

Centisome position: 46.34

GC content: 62.38

Gene sequence:

>933_bases
ATGGCCAGCTACGACCTCGTTGAACGTCTGAATAATACCTTTCGCCAGATCGAGCTGGAGCTGCAGGCGCTCCAGCAGGC
GTTAAGTGACTGCCGTCTGCTGGCGGGCCGGGTATTTGAACTGCCGGCGATCGGTAAGGATGCCGAGCACGATCCGCTGG
CCACTATTCCGGTGGTGCAGCACATCGGCAAGACGGCCCTGGCGCGCGCCCTGCGCCACTACAGCCATCTGTTTATCCAG
CAGCAATCGGAAAACCGCAGCAGCAAGGCCGCCGTACGCCTGCCGGGGGCTATCTGCCTGCAGGTTACCGCCGCGGAGCA
GCAGGATCTGCTGGCGCGTATTCAGCATATCAATGCCCTGAAGGCCACCTTCGAGAAGATCGTCACCGTCGACTCCGGCC
TGCCCCCCACCGCCCGTTTTGAGTGGGTACACCGTCATTTGCCGGGGTTGATCACCCTTAGCGCCTACCGCACGCTGACG
CCCCTCGTCGACCCGAGCACCATCCGCTTCGGCTGGGCCAATAAGCACGTCATCAAGAATCTGACCCGCGACCAGGTGTT
GATGATGCTGGAGAAAAGCCTGCAAGCGCCGCGGGCGGTGCCGCCGTGGACCCGGGAGCAGTGGCAGAGCAAACTGGAAA
GGGAGTATCAGGATATCGCCGCCCTGCCGCAGCGGGCGCGGCTGAAAATAAAACGACCGGTGAAAGTCCAGCCGATCGCC
CGCGTCTGGTACGCCGGCGAGCAGAAACAGGTACAGTACGCCTGCCCCAGCCCGCTGATCGCCCTGATGTCCGGCAGCCG
GGGGGTCAGCGTACCGGATATTGGCGAGCTGCTGAACTATGATGCCGACAATGTGCAGTATCGCTACAAACCGGAGGCGC
AGTCGCTGAGATTGCTTATCCCGCGCCTGCACCTCTGGCTGGCTAGCGAATAG

Upstream 100 bases:

>100_bases
GCTGCCTGATTTCACCTCTGCCTGAATAAAACTTGCGCAGAAGCCGCGGGCTGGGTATGCTGCAAAAATCTAATAGTATG
TTGTAACTAAGGTGGTAATA

Downstream 100 bases:

>100_bases
CCAGGCTGCCGACCATCTCTTCCGGGCGCACCCAGCTGTCGAATTCGGCTTCCGTCAGGTAGCCCAGCGCCAGCGCCGAG
GCTTTGAGAGTCAGCCCCTC

Product: DNA replication terminus site-binding protein

Products: NA

Alternate protein names: Ter-binding protein [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MASYDLVERLNNTFRQIELELQALQQALSDCRLLAGRVFELPAIGKDAEHDPLATIPVVQHIGKTALARALRHYSHLFIQ
QQSENRSSKAAVRLPGAICLQVTAAEQQDLLARIQHINALKATFEKIVTVDSGLPPTARFEWVHRHLPGLITLSAYRTLT
PLVDPSTIRFGWANKHVIKNLTRDQVLMMLEKSLQAPRAVPPWTREQWQSKLEREYQDIAALPQRARLKIKRPVKVQPIA
RVWYAGEQKQVQYACPSPLIALMSGSRGVSVPDIGELLNYDADNVQYRYKPEAQSLRLLIPRLHLWLASE

Sequences:

>Translated_310_residues
MASYDLVERLNNTFRQIELELQALQQALSDCRLLAGRVFELPAIGKDAEHDPLATIPVVQHIGKTALARALRHYSHLFIQ
QQSENRSSKAAVRLPGAICLQVTAAEQQDLLARIQHINALKATFEKIVTVDSGLPPTARFEWVHRHLPGLITLSAYRTLT
PLVDPSTIRFGWANKHVIKNLTRDQVLMMLEKSLQAPRAVPPWTREQWQSKLEREYQDIAALPQRARLKIKRPVKVQPIA
RVWYAGEQKQVQYACPSPLIALMSGSRGVSVPDIGELLNYDADNVQYRYKPEAQSLRLLIPRLHLWLASE
>Mature_309_residues
ASYDLVERLNNTFRQIELELQALQQALSDCRLLAGRVFELPAIGKDAEHDPLATIPVVQHIGKTALARALRHYSHLFIQQ
QSENRSSKAAVRLPGAICLQVTAAEQQDLLARIQHINALKATFEKIVTVDSGLPPTARFEWVHRHLPGLITLSAYRTLTP
LVDPSTIRFGWANKHVIKNLTRDQVLMMLEKSLQAPRAVPPWTREQWQSKLEREYQDIAALPQRARLKIKRPVKVQPIAR
VWYAGEQKQVQYACPSPLIALMSGSRGVSVPDIGELLNYDADNVQYRYKPEAQSLRLLIPRLHLWLASE

Specific function: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tus family [H]

Homologues:

Organism=Escherichia coli, GI1787895, Length=309, Percent_Identity=70.2265372168285, Blast_Score=455, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008865 [H]

Pfam domain/function: PF05472 Ter [H]

EC number: NA

Molecular weight: Translated: 35188; Mature: 35057

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYDLVERLNNTFRQIELELQALQQALSDCRLLAGRVFELPAIGKDAEHDPLATIPVVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
HIGKTALARALRHYSHLFIQQQSENRSSKAAVRLPGAICLQVTAAEQQDLLARIQHINAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEEEHHHHHHHHHHHHHHHHH
KATFEKIVTVDSGLPPTARFEWVHRHLPGLITLSAYRTLTPLVDPSTIRFGWANKHVIKN
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHHHHCCCCCCCEEEECCCCHHHHHH
LTRDQVLMMLEKSLQAPRAVPPWTREQWQSKLEREYQDIAALPQRARLKIKRPVKVQPIA
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCEEECCCCCCCHHH
RVWYAGEQKQVQYACPSPLIALMSGSRGVSVPDIGELLNYDADNVQYRYKPEAQSLRLLI
HHHCCCCCCEEEECCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHH
PRLHLWLASE
HHHHHHCCCC
>Mature Secondary Structure 
ASYDLVERLNNTFRQIELELQALQQALSDCRLLAGRVFELPAIGKDAEHDPLATIPVVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
HIGKTALARALRHYSHLFIQQQSENRSSKAAVRLPGAICLQVTAAEQQDLLARIQHINAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEEEEEEHHHHHHHHHHHHHHHHH
KATFEKIVTVDSGLPPTARFEWVHRHLPGLITLSAYRTLTPLVDPSTIRFGWANKHVIKN
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHHHHCCCCCCCEEEECCCCHHHHHH
LTRDQVLMMLEKSLQAPRAVPPWTREQWQSKLEREYQDIAALPQRARLKIKRPVKVQPIA
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCEEECCCCCCCHHH
RVWYAGEQKQVQYACPSPLIALMSGSRGVSVPDIGELLNYDADNVQYRYKPEAQSLRLLI
HHHCCCCCCEEEECCCCHHHHHHCCCCCCCCCCHHHHHCCCCCCCEEEECCCHHHHHHHH
PRLHLWLASE
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA