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The map label for this gene is yccK [H]

Identifier: 238894503

GI number: 238894503

Start: 2399788

End: 2400786

Strand: Direct

Name: yccK [H]

Synonym: KP1_2494

Alternate gene names: 238894503

Gene position: 2399788-2400786 (Clockwise)

Preceding gene: 238894496

Following gene: 238894507

Centisome position: 45.72

GC content: 55.96

Gene sequence:

>999_bases
ATGAAAACACGTTATCTTGGAAAAGAGAAGTTTCAGGTTTCCGCATTAGGTCTCGGATGTATGGGGATGAGTTTTGCCTA
TGGCGGCGCTGAAACGTCGCAGGCGATAAATACGATCCATACCGCCATGGACATGGGCGTGACCTTCCTGGATACCGCCG
AAGTATATGGTCCTTTCGATAATGAAGTTCTGGTCGGAAAAGCGATTAAAGGTTTTCGCGATAAGGTGCAGATTGCCACC
AAATTTGGATTTCGTATTTTGCCGACCGGCCAGGGTCTGGAGCGGATGGCCGGCGTTGACAGCCGTCCGGCACATATTCG
CGAATCAGTGGAAGGGTCGCTGAAGCGACTGAATGTCGAGACCATCGATCTGCTCTATCAGCACCGCGTCGATCCCGCGG
TACCGGTGGAAGAGGTGGTGGGCACTATGGCCGATCTGGTTAAAGAGGGTAAAATTCGCCATATCGGTCTGTCGGAAGTA
TCTGCTCAGACGCTGCGCCGGGCCTGCAAGGTACATCCGATCGCTGCCGTGCAGACGGAATATTCGCTATGGAGCCGCGA
GCCGGAGGGCGATATTCTCCACACCTGCCGCGAGCTGGGGGTCGGCTTTGTGCCATACAGCCCGCTTGGCCGCGGCTTCC
TGACGGGGACAATTACCGATCCCGGCGTTTTGGCAGCGGATGATTTCCGCCGCCATCTGCCGCGCTTCCAGGCCAAAACC
ATGCGCAAAAACCAGCTGCTGCTTGAGCGCCTTCAGCAGGTGGCCACCCGCTATGACGCGACCCTTGCGCAGATTGCCCT
TGCCTGGGTGATGAGCAAAGGCGAGGATATCGTGCCTATCCCGGGGGCGAGGAAAATTGCTCACCTGCGCGACAATGCCG
GCGCCGCGAATATTACCCTCGCGCCGGAGGACATCCTCACCATCGAACATATTTTCACTGCCGACAACGTCACTGGCTTA
CGCTATACCCAGGGCGACTTTGATTTAATCGAAAAATAA

Upstream 100 bases:

>100_bases
TGTTAATTTCCAGCTAACACCGCGTTCGGAATAGATTAATTGTTATCAATATGAAAGGGAAGTATATATTTAATGCCATT
CAGCAATTAAGGAAAATAAG

Downstream 100 bases:

>100_bases
TCCCCTGCGGGCAGCGGATGGTTATTACTTGCGTGACGTTGTCACCTTTACCGAACTACTCCTCGTCAGATAGCGCACAT
CCTCGGCGGTTAACGGCGCG

Product: putative aldo-keto reductase/oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKTRYLGKEKFQVSALGLGCMGMSFAYGGAETSQAINTIHTAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIAT
KFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEV
SAQTLRRACKVHPIAAVQTEYSLWSREPEGDILHTCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAKT
MRKNQLLLERLQQVATRYDATLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGL
RYTQGDFDLIEK

Sequences:

>Translated_332_residues
MKTRYLGKEKFQVSALGLGCMGMSFAYGGAETSQAINTIHTAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIAT
KFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEV
SAQTLRRACKVHPIAAVQTEYSLWSREPEGDILHTCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAKT
MRKNQLLLERLQQVATRYDATLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGL
RYTQGDFDLIEK
>Mature_332_residues
MKTRYLGKEKFQVSALGLGCMGMSFAYGGAETSQAINTIHTAMDMGVTFLDTAEVYGPFDNEVLVGKAIKGFRDKVQIAT
KFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVETIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEV
SAQTLRRACKVHPIAAVQTEYSLWSREPEGDILHTCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAKT
MRKNQLLLERLQQVATRYDATLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITLAPEDILTIEHIFTADNVTGL
RYTQGDFDLIEK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=345, Percent_Identity=30.7246376811594, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI4504825, Length=342, Percent_Identity=30.7017543859649, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI27436964, Length=345, Percent_Identity=30.4347826086957, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI27436962, Length=343, Percent_Identity=29.7376093294461, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436966, Length=345, Percent_Identity=30.1449275362319, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI27436971, Length=328, Percent_Identity=29.2682926829268, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI223718702, Length=297, Percent_Identity=28.2828282828283, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI41327764, Length=183, Percent_Identity=30.0546448087432, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI41152114, Length=196, Percent_Identity=29.5918367346939, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI87081735, Length=339, Percent_Identity=33.6283185840708, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=34.2857142857143, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1789375, Length=335, Percent_Identity=29.2537313432836, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787674, Length=284, Percent_Identity=28.169014084507, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788081, Length=305, Percent_Identity=26.2295081967213, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789199, Length=339, Percent_Identity=27.1386430678466, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI48994888, Length=282, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=301, Percent_Identity=28.9036544850498, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=28.3489096573209, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325384, Length=342, Percent_Identity=28.0701754385965, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=29.7297297297297, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=25.2906976744186, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=329, Percent_Identity=25.8358662613982, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646155, Length=171, Percent_Identity=33.9181286549708, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24646159, Length=227, Percent_Identity=27.7533039647577, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644950, Length=291, Percent_Identity=22.680412371134, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36562; Mature: 36562

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRYLGKEKFQVSALGLGCMGMSFAYGGAETSQAINTIHTAMDMGVTFLDTAEVYGPFD
CCCCCCCCCCEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCC
NEVLVGKAIKGFRDKVQIATKFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVE
CCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHCCHH
TIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHH
YSLWSREPEGDILHTCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAKT
HHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEHHHHHHHCCHHHHHH
MRKNQLLLERLQQVATRYDATLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCCEEEE
APEDILTIEHIFTADNVTGLRYTQGDFDLIEK
CCHHHEEHHHEEECCCCCCCEEECCCHHHHCC
>Mature Secondary Structure
MKTRYLGKEKFQVSALGLGCMGMSFAYGGAETSQAINTIHTAMDMGVTFLDTAEVYGPFD
CCCCCCCCCCEEEEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHCCCCC
NEVLVGKAIKGFRDKVQIATKFGFRILPTGQGLERMAGVDSRPAHIRESVEGSLKRLNVE
CCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHCCHH
TIDLLYQHRVDPAVPVEEVVGTMADLVKEGKIRHIGLSEVSAQTLRRACKVHPIAAVQTE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHH
YSLWSREPEGDILHTCRELGVGFVPYSPLGRGFLTGTITDPGVLAADDFRRHLPRFQAKT
HHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCEEHHHHHHHCCHHHHHH
MRKNQLLLERLQQVATRYDATLAQIALAWVMSKGEDIVPIPGARKIAHLRDNAGAANITL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHCCCCCCEEEE
APEDILTIEHIFTADNVTGLRYTQGDFDLIEK
CCHHHEEHHHEEECCCCCCCEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]