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The map label for this gene is 238894476

Identifier: 238894476

GI number: 238894476

Start: 2370068

End: 2370892

Strand: Direct

Name: 238894476

Synonym: KP1_2467

Alternate gene names: NA

Gene position: 2370068-2370892 (Clockwise)

Preceding gene: 238894475

Following gene: 238894477

Centisome position: 45.16

GC content: 68.36

Gene sequence:

>825_bases
CTGTTTGAGAGGGGGAGGGCGCCGATGGTCTGCGGGCGTACCGCCCATTCGGCGCTGGTGCTGCGCACTGACGAGGGTGA
GATCGTGGTGCCCGGCCCGGTGCACACCGACCCGATGGCGATAGCCGCCCCCTTCGACCTGGTCTTTGTCGCGGTGAAAA
CCACCCAGACGGAGGCCATCGCCCCCTGGCTGACGGCCCTGTGTTCCCCTGACACCGTGGTGTGCGTGCTGCAAAACGGC
GTTGAGCAGCGCCAGCAGTTTGCCCCCTTGACCGGCGGCGCGACGGTGCTGCCGTCGGTGGTCTGGTTCCCGGCGCAGCG
CGATGCCGATGCCTCTGTCTGGCTGCGCGCCACGCCGCGCCTGACGCTGCCGGATCTGCCGGGGGCAGAGCGGGTGCAGC
AGGCGCTGGCGGGAACCCGCTGCGCGGTGGACCTGGCGGCTGATTTTACCACCGTGGCCTGGCGCAAACTGTTGCAGAAC
GCGGTTGCCGGGCTGATGGTGCTGACCGGACGACGCGCCGGGATGTTCGCCCGGGAGGACATCACTGCCCTCGGACTGGC
TTATATGCGCGAATGCCTGCAGGTGGCGCGGGCGGAAGGGGCCGCCCTGAGCGACAACGTGCCGGAGGAGATTATCGCCG
GCTTTCATCGGGCGCCTGCCGACTTAAGCACCTCGATTATGATCGATCGCCTCAATGGCCGACCGCTGGAGTGGGATATT
CGTAACGGCGTGGTGCAGCGTCGCGGGCGTCAGCACGGCATTCCGACGCCGCTCAGCGATATCATCGTGCCGTTGCTGGC
GGCGGCCAGCGACGGCCCGGGCTGA

Upstream 100 bases:

>100_bases
AATCTGGGCGGTGAATCATCAGGAGGTCTTCGGCATGACAGCATTTCCTAAGGTTGCGCTAATTGGTCCCGGCGCCATCG
GCACCACGATTGCCGCCGCC

Downstream 100 bases:

>100_bases
CCCGGGCTGGCGCGGGTGCGAGCCACTGGAAGCGGGATCTGCTATGATCCCGACTTTCGTTGTCTGGAGCCAGTCGATGT
TCAACGACGCCATTGTTTAT

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MFERGRAPMVCGRTAHSALVLRTDEGEIVVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAIAPWLTALCSPDTVVCVLQNG
VEQRQQFAPLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAADFTTVAWRKLLQN
AVAGLMVLTGRRAGMFAREDITALGLAYMRECLQVARAEGAALSDNVPEEIIAGFHRAPADLSTSIMIDRLNGRPLEWDI
RNGVVQRRGRQHGIPTPLSDIIVPLLAAASDGPG

Sequences:

>Translated_274_residues
MFERGRAPMVCGRTAHSALVLRTDEGEIVVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAIAPWLTALCSPDTVVCVLQNG
VEQRQQFAPLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAADFTTVAWRKLLQN
AVAGLMVLTGRRAGMFAREDITALGLAYMRECLQVARAEGAALSDNVPEEIIAGFHRAPADLSTSIMIDRLNGRPLEWDI
RNGVVQRRGRQHGIPTPLSDIIVPLLAAASDGPG
>Mature_274_residues
MFERGRAPMVCGRTAHSALVLRTDEGEIVVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAIAPWLTALCSPDTVVCVLQNG
VEQRQQFAPLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAADFTTVAWRKLLQN
AVAGLMVLTGRRAGMFAREDITALGLAYMRECLQVARAEGAALSDNVPEEIIAGFHRAPADLSTSIMIDRLNGRPLEWDI
RNGVVQRRGRQHGIPTPLSDIIVPLLAAASDGPG

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 29341; Mature: 29341

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERGRAPMVCGRTAHSALVLRTDEGEIVVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAI
CCCCCCCCEEECCCCCCEEEEEECCCCEEECCCCCCCCEEEECCCEEEEEEEECCCCHHH
APWLTALCSPDTVVCVLQNGVEQRQQFAPLTGGATVLPSVVWFPAQRDADASVWLRATPR
HHHHHHHCCCCEEEEEEHHCHHHHHHHCCCCCCHHHHHHHHEECCCCCCCCEEEEEECCC
LTLPDLPGAERVQQALAGTRCAVDLAADFTTVAWRKLLQNAVAGLMVLTGRRAGMFARED
CCCCCCCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
ITALGLAYMRECLQVARAEGAALSDNVPEEIIAGFHRAPADLSTSIMIDRLNGRPLEWDI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCEEHH
RNGVVQRRGRQHGIPTPLSDIIVPLLAAASDGPG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFERGRAPMVCGRTAHSALVLRTDEGEIVVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAI
CCCCCCCCEEECCCCCCEEEEEECCCCEEECCCCCCCCEEEECCCEEEEEEEECCCCHHH
APWLTALCSPDTVVCVLQNGVEQRQQFAPLTGGATVLPSVVWFPAQRDADASVWLRATPR
HHHHHHHCCCCEEEEEEHHCHHHHHHHCCCCCCHHHHHHHHEECCCCCCCCEEEEEECCC
LTLPDLPGAERVQQALAGTRCAVDLAADFTTVAWRKLLQNAVAGLMVLTGRRAGMFARED
CCCCCCCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
ITALGLAYMRECLQVARAEGAALSDNVPEEIIAGFHRAPADLSTSIMIDRLNGRPLEWDI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCEEHH
RNGVVQRRGRQHGIPTPLSDIIVPLLAAASDGPG
HHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]