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The map label for this gene is feaR [H]

Identifier: 238894474

GI number: 238894474

Start: 2367240

End: 2368202

Strand: Reverse

Name: feaR [H]

Synonym: KP1_2464

Alternate gene names: 238894474

Gene position: 2368202-2367240 (Counterclockwise)

Preceding gene: 238894478

Following gene: 238894469

Centisome position: 45.12

GC content: 62.1

Gene sequence:

>963_bases
TTGCCTGAGGCGACACAAATGCAACAATGCGGAAACATTGTTATTACAGGAGAAGGGCGAATGATGACCACGGCAGAGGG
GGGGCTGGCGTATCAGCGCTGGCTGGCGACGATCAATCAGGTCTGCGGCCATTTCGCCGCCCGGCCGCTGAAGGAGAGTT
TCCACGGCGAGATTGACGCCCGCTACGCCGGCAGCCTCAAGGTCAGTACCGTCACCGCCGCCGGCGTCAATCTCTACCGC
ACGCGCAATGAGATAAAACGCGATAACGACGCCTGGTTCTATACCGTGTTTCAGCTCGCCGGCGAAGCCATCATCGAACA
GGACGATCGCCAGGTGACGCTGGCGGCAGGCGATATCACGTTAATCGACGCCGCCCGCCCATGCTCCATCGTCTGGCAGC
AGACTTCGCGTCAGGCCTCGCTGCTGCTGCCGCGCCAGCGGGTGGCGCCCACAGGGGACATCACTACCGCCTGCCGGCTG
GACAAATCTCTGCCAATGGTCCAGCTCAGCCAGCGACTGCTGCTGGAAAGCATGGGCGGCACGACGCTCTCCGCCAGCGA
GAGCGAAGCCGCGCTGGAGGCGATCGCCTGCCTGTTGCGCCCGGTGCTGCATCAGCGCGATCCTGCCCCTTCCCGGCGGG
TAAAGCAGTTTCAGAAGATTATTGCGTTAATCGATGCGTCCATTCAGTCGGAGCATCTGCGTCCGGAGTGGCTGGCCAGC
GAGACGGGCATGTCGGTACGCAGCCTGTACCGGCTGTTTGCCGACCAGGGGCTGGTGGTGGCGCAGTATATTAAGAACCG
GCGGTTGGATCTGTGTGCCCAGGCGTTACAGAACGTCCATGACGATGAAAAGCTGGCGGGGATCGGCTACCGCTGGGGCT
TCAGCGACCACAGCCATTTCTCCACCGCCTTTAAGCAGCGCTTTGGCGTCACCCCGGGGCAATACCGCAAGCGCTGTCGC
TAA

Upstream 100 bases:

>100_bases
ATTCGTTTGCGCCGCTGTGACAGTCGCCGCAATTCCGTCGTCTGCCCTCGCAGAAATGTGCCGCGGGTAATAGTTCTTTC
ATATACCCGCCATCGCGCCC

Downstream 100 bases:

>100_bases
TTATTTGCGCAGCCACTGGCCGTTCAATCCCTGGACGTACTCCCCGGGCTGCGCGCGGGCCACCAGCTTCTGCCCGGCCA
TTTTCGCCACTTCATCCACC

Product: DNA-binding transcriptional activator FeaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPEATQMQQCGNIVITGEGRMMTTAEGGLAYQRWLATINQVCGHFAARPLKESFHGEIDARYAGSLKVSTVTAAGVNLYR
TRNEIKRDNDAWFYTVFQLAGEAIIEQDDRQVTLAAGDITLIDAARPCSIVWQQTSRQASLLLPRQRVAPTGDITTACRL
DKSLPMVQLSQRLLLESMGGTTLSASESEAALEAIACLLRPVLHQRDPAPSRRVKQFQKIIALIDASIQSEHLRPEWLAS
ETGMSVRSLYRLFADQGLVVAQYIKNRRLDLCAQALQNVHDDEKLAGIGYRWGFSDHSHFSTAFKQRFGVTPGQYRKRCR

Sequences:

>Translated_320_residues
MPEATQMQQCGNIVITGEGRMMTTAEGGLAYQRWLATINQVCGHFAARPLKESFHGEIDARYAGSLKVSTVTAAGVNLYR
TRNEIKRDNDAWFYTVFQLAGEAIIEQDDRQVTLAAGDITLIDAARPCSIVWQQTSRQASLLLPRQRVAPTGDITTACRL
DKSLPMVQLSQRLLLESMGGTTLSASESEAALEAIACLLRPVLHQRDPAPSRRVKQFQKIIALIDASIQSEHLRPEWLAS
ETGMSVRSLYRLFADQGLVVAQYIKNRRLDLCAQALQNVHDDEKLAGIGYRWGFSDHSHFSTAFKQRFGVTPGQYRKRCR
>Mature_319_residues
PEATQMQQCGNIVITGEGRMMTTAEGGLAYQRWLATINQVCGHFAARPLKESFHGEIDARYAGSLKVSTVTAAGVNLYRT
RNEIKRDNDAWFYTVFQLAGEAIIEQDDRQVTLAAGDITLIDAARPCSIVWQQTSRQASLLLPRQRVAPTGDITTACRLD
KSLPMVQLSQRLLLESMGGTTLSASESEAALEAIACLLRPVLHQRDPAPSRRVKQFQKIIALIDASIQSEHLRPEWLASE
TGMSVRSLYRLFADQGLVVAQYIKNRRLDLCAQALQNVHDDEKLAGIGYRWGFSDHSHFSTAFKQRFGVTPGQYRKRCR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=293, Percent_Identity=63.481228668942, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 35711; Mature: 35580

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEATQMQQCGNIVITGEGRMMTTAEGGLAYQRWLATINQVCGHFAARPLKESFHGEIDA
CCCHHHHHHCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RYAGSLKVSTVTAAGVNLYRTRNEIKRDNDAWFYTVFQLAGEAIIEQDDRQVTLAAGDIT
EECCCEEEEEEEHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCEE
LIDAARPCSIVWQQTSRQASLLLPRQRVAPTGDITTACRLDKSLPMVQLSQRLLLESMGG
EEECCCCHHHHHHHCCCHHHHCCCHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCC
TTLSASESEAALEAIACLLRPVLHQRDPAPSRRVKQFQKIIALIDASIQSEHLRPEWLAS
CEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ETGMSVRSLYRLFADQGLVVAQYIKNRRLDLCAQALQNVHDDEKLAGIGYRWGFSDHSHF
HCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCEEECCCCCCHHH
STAFKQRFGVTPGQYRKRCR
HHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
PEATQMQQCGNIVITGEGRMMTTAEGGLAYQRWLATINQVCGHFAARPLKESFHGEIDA
CCHHHHHHCCCEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RYAGSLKVSTVTAAGVNLYRTRNEIKRDNDAWFYTVFQLAGEAIIEQDDRQVTLAAGDIT
EECCCEEEEEEEHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCEE
LIDAARPCSIVWQQTSRQASLLLPRQRVAPTGDITTACRLDKSLPMVQLSQRLLLESMGG
EEECCCCHHHHHHHCCCHHHHCCCHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCC
TTLSASESEAALEAIACLLRPVLHQRDPAPSRRVKQFQKIIALIDASIQSEHLRPEWLAS
CEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ETGMSVRSLYRLFADQGLVVAQYIKNRRLDLCAQALQNVHDDEKLAGIGYRWGFSDHSHF
HCCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCHHHHCCEEECCCCCCHHH
STAFKQRFGVTPGQYRKRCR
HHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]