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The map label for this gene is qor [H]

Identifier: 238894446

GI number: 238894446

Start: 2338096

End: 2339130

Strand: Direct

Name: qor [H]

Synonym: KP1_2434

Alternate gene names: 238894446

Gene position: 2338096-2339130 (Clockwise)

Preceding gene: 238894444

Following gene: 238894448

Centisome position: 44.55

GC content: 66.96

Gene sequence:

>1035_bases
ATGTCGACGCAGATGATGAAGGCTGTTCAACAGCACGCCTTTGGCGGGCCGGAAGTCCTGAGCTATGAGGATGCGCCCAT
GCCGGTGCTGCAGGCCGGCGAGGTGCTGGTGCAGGTGCACGCGGTGGGCGTGAACCCGCCGGACAGCTATCTGCGCGATG
GCTATCAACAGCTGCCCCCGGAGTGGCGGCCCGAGGTCCGCTTTCCCTTGATCCTCGGGACCGATCTCTCCGGGGTGGTG
GTGGCGCGGGCGGATGACGTCCGGGAGGTGGCGGTCGGCGACGAAGTGTATGCTATGGCGCGTTTTCCCGAAGGGGCGGC
AGGGGGCAGCCGCGCTTACGCCGAGTACGTTAGCGTGCCGGTCAGCGACCTCGCTCGCAAACCCCTAACCCTGATCCATC
AGCAGGCTGCCGCGGTGCCGATGTCGCTCCTCACCGCCTGGCAGTTCATGATCGATCCCGGGCATGAGGTGGCGAATCCG
CTGCAGCCGGGGCCGCATCGGCCGGTGCCGCTGGCGGGTAAACGCGTCCTGGTCAACGGCGCGGCAGGGGGAGTCGGTCA
TTTCGCCGTGCAGCTGGCGAAGTGGCAGGGCGCCGAGGTGATTGCCGTCGCCGCGGGCCGCCATGAAGCCTTTTTACGTC
AGCTCGGCGCCGATAGCGTTATCGACTATACAACCACCGCAGTGGAGGAGACGGTGCGTGACCTGGATCTGGTCATTGAT
GCGCCGGGCGGGCCGGCCAGCGGCCGTTTTTTGCGTACCCTGCGACCCGGCGGCGCGCTGTACCCGATCTTTCCGCTCGG
CTTTGCCGGGGCGGAAGAGGCGCGACAGCGCGGAGTGACGGTCTCCACCACCCAGGTACGCTCCAGCGGCGCGCAGCTCG
CCCGGCTTGCCGACCTGCTGGACGCCGGGATCATCCGGGTTGCAATTGACAGCGTTTTCCCCCTTGCGCAGGCGCAGATG
GCGCATGAGCGAGCAGCGCAGGGGCATCTTGAGGGCAAAATCGTGCTGTCGGTGATGGACTCGTCAGCCGGGTAA

Upstream 100 bases:

>100_bases
ATCAGCTCTCATTGGCGTTCCTTGACAATCGGAGCACTGCTCCATATATTCGGAACAGTGCTCCGTTAAATATAACGCAT
TTCCATATGAGGAGAAAGCG

Downstream 100 bases:

>100_bases
TCCCCGACGGCCAGGGTTGCGTTTTTGCTTCTCCCGGCGGCGGACTAAAACAGCGCCAGCCGGGCAAGACGGTCCAGCGC
GTTGCTCAGCGCCTCGTCCC

Product: zinc-binding oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSTQMMKAVQQHAFGGPEVLSYEDAPMPVLQAGEVLVQVHAVGVNPPDSYLRDGYQQLPPEWRPEVRFPLILGTDLSGVV
VARADDVREVAVGDEVYAMARFPEGAAGGSRAYAEYVSVPVSDLARKPLTLIHQQAAAVPMSLLTAWQFMIDPGHEVANP
LQPGPHRPVPLAGKRVLVNGAAGGVGHFAVQLAKWQGAEVIAVAAGRHEAFLRQLGADSVIDYTTTAVEETVRDLDLVID
APGGPASGRFLRTLRPGGALYPIFPLGFAGAEEARQRGVTVSTTQVRSSGAQLARLADLLDAGIIRVAIDSVFPLAQAQM
AHERAAQGHLEGKIVLSVMDSSAG

Sequences:

>Translated_344_residues
MSTQMMKAVQQHAFGGPEVLSYEDAPMPVLQAGEVLVQVHAVGVNPPDSYLRDGYQQLPPEWRPEVRFPLILGTDLSGVV
VARADDVREVAVGDEVYAMARFPEGAAGGSRAYAEYVSVPVSDLARKPLTLIHQQAAAVPMSLLTAWQFMIDPGHEVANP
LQPGPHRPVPLAGKRVLVNGAAGGVGHFAVQLAKWQGAEVIAVAAGRHEAFLRQLGADSVIDYTTTAVEETVRDLDLVID
APGGPASGRFLRTLRPGGALYPIFPLGFAGAEEARQRGVTVSTTQVRSSGAQLARLADLLDAGIIRVAIDSVFPLAQAQM
AHERAAQGHLEGKIVLSVMDSSAG
>Mature_343_residues
STQMMKAVQQHAFGGPEVLSYEDAPMPVLQAGEVLVQVHAVGVNPPDSYLRDGYQQLPPEWRPEVRFPLILGTDLSGVVV
ARADDVREVAVGDEVYAMARFPEGAAGGSRAYAEYVSVPVSDLARKPLTLIHQQAAAVPMSLLTAWQFMIDPGHEVANPL
QPGPHRPVPLAGKRVLVNGAAGGVGHFAVQLAKWQGAEVIAVAAGRHEAFLRQLGADSVIDYTTTAVEETVRDLDLVIDA
PGGPASGRFLRTLRPGGALYPIFPLGFAGAEEARQRGVTVSTTQVRSSGAQLARLADLLDAGIIRVAIDSVFPLAQAQMA
HERAAQGHLEGKIVLSVMDSSAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=374, Percent_Identity=33.1550802139037, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI194239674, Length=349, Percent_Identity=27.2206303724928, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI13236495, Length=349, Percent_Identity=27.2206303724928, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI194239676, Length=336, Percent_Identity=26.7857142857143, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI24308257, Length=260, Percent_Identity=31.1538461538462, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI18379349, Length=341, Percent_Identity=26.9794721407625, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI22538446, Length=367, Percent_Identity=27.7929155313352, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI22538444, Length=367, Percent_Identity=27.7929155313352, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI28557745, Length=230, Percent_Identity=30, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=362, Percent_Identity=26.2430939226519, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=363, Percent_Identity=27.8236914600551, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71987554, Length=365, Percent_Identity=28.4931506849315, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=249, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319945, Length=239, Percent_Identity=28.4518828451883, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323493, Length=239, Percent_Identity=28.0334728033473, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24581339, Length=375, Percent_Identity=29.0666666666667, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24581341, Length=371, Percent_Identity=29.3800539083558, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 36423; Mature: 36292

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQMMKAVQQHAFGGPEVLSYEDAPMPVLQAGEVLVQVHAVGVNPPDSYLRDGYQQLPP
CCHHHHHHHHHHCCCCCCEECCCCCCCCHHHHCCEEEEEEEECCCCCHHHHHCHHHHCCC
EWRPEVRFPLILGTDLSGVVVARADDVREVAVGDEVYAMARFPEGAAGGSRAYAEYVSVP
CCCCCCEEEEEECCCCCCEEEECCCCHHHHHCCCHHEEEEECCCCCCCCHHHHHHHHCCC
VSDLARKPLTLIHQQAAAVPMSLLTAWQFMIDPGHEVANPLQPGPHRPVPLAGKRVLVNG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCEEEEEC
AAGGVGHFAVQLAKWQGAEVIAVAAGRHEAFLRQLGADSVIDYTTTAVEETVRDLDLVID
CCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEE
APGGPASGRFLRTLRPGGALYPIFPLGFAGAEEARQRGVTVSTTQVRSSGAQLARLADLL
CCCCCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
DAGIIRVAIDSVFPLAQAQMAHERAAQGHLEGKIVLSVMDSSAG
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
STQMMKAVQQHAFGGPEVLSYEDAPMPVLQAGEVLVQVHAVGVNPPDSYLRDGYQQLPP
CHHHHHHHHHHCCCCCCEECCCCCCCCHHHHCCEEEEEEEECCCCCHHHHHCHHHHCCC
EWRPEVRFPLILGTDLSGVVVARADDVREVAVGDEVYAMARFPEGAAGGSRAYAEYVSVP
CCCCCCEEEEEECCCCCCEEEECCCCHHHHHCCCHHEEEEECCCCCCCCHHHHHHHHCCC
VSDLARKPLTLIHQQAAAVPMSLLTAWQFMIDPGHEVANPLQPGPHRPVPLAGKRVLVNG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCEEEEEC
AAGGVGHFAVQLAKWQGAEVIAVAAGRHEAFLRQLGADSVIDYTTTAVEETVRDLDLVID
CCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEE
APGGPASGRFLRTLRPGGALYPIFPLGFAGAEEARQRGVTVSTTQVRSSGAQLARLADLL
CCCCCCCCCEEEEECCCCCEEECCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
DAGIIRVAIDSVFPLAQAQMAHERAAQGHLEGKIVLSVMDSSAG
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]